Patents by Inventor Sainitin Donakonda

Sainitin Donakonda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thymine derivatives and quinazoline-dione derivatives for the inhibition of HSP27
    Patent number: 10940150
    Abstract: The present invention relates to novel HSP27 inhibitors, in particular thymine derivatives according to general formula (VI), (VII) or (VII) and phenothiazine derivatives according to formula (V), and to their use as drugs for the selective inhibition of the heat shock protein HSP27 (HSPB1), in particular for use in the treatment of carcinomas or cystic fibrosis, said inhibitors having a particularly advantageous activity in the lower micromolar or sub-micromolar active ingredient concentration range with respect to HSP27.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: March 9, 2021
    Assignee: Technische Universitaet Dresden
    Inventors: Michael Schroeder, Yixin Zhang, Joerg-Christian Heinrich, Joachim Haupt, Sainitin Donakonda, Petra Lennig
  • THYMINE DERIVATIVES AND QUINAZOLINE-DIONE DERIVATIVES FOR THE INHIBITION OF HSP27
    Publication number: 20180207160
    Abstract: The present invention relates to novel HSP27 inhibitors, in particular thymine derivatives according to general formula (VI), (VII) or (VII) and phenothiazine derivatives according to formula (V), and to their use as drugs for the selective inhibition of the heat shock protein HSP27 (HSPB1), in particular for use in the treatment of carcinomas or cystic fibrosis, said inhibitors having a particularly advantageous activity in the lower micromolar or sub-micromolar active ingredient concentration range with respect to HSP27.
    Type: Application
    Filed: July 28, 2015
    Publication date: July 26, 2018
    Applicant: TECHNISCHE UNIVERSITAET DRESDEN
    Inventors: Michael Schroeder, Yixin Zhang, Joerg-Christian Heinrich, Joachim Haupt, Sainitin Donakonda, Petra Lennig
  • EFFICIENT INHIBITION OF HSP27
    Publication number: 20170216297
    Abstract: The present invention relates to novel HSP27 inhibitors, in particular purine derivatives according to general formula (I) or (II) and phenothiazine derivatives according to formula (V), and to their use as drugs for the selective inhibition of the heat shock protein HSP27 (HSPB1), in particular for use in the treatment of carcinomas or cystic fibrosis, said inhibitors having a particularly advantageous activity in the lower micromolar or sub-micromolar active ingredient concentration range with respect to HSP2.
    Type: Application
    Filed: July 28, 2015
    Publication date: August 3, 2017
    Applicant: TECHNISCHE UNIVERSITAET DRESDEN
    Inventors: Michael Schroeder, Yixin Zhang, Joerg-Christian Heinrich, Joachim Haupt, Sainitin Donakonda, Petra Lennig