Patents by Inventor Sajad Hussain SYED

Sajad Hussain SYED has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolopyrimidinones for the treatment of impotence and process for the preparation thereof
    Patent number: 10017511
    Abstract: The present invention relates to Pyrazolopyrimidinone compounds as PDE5 inhibitors with better IC50 value, good in vivo efficacy and PK profile and a process for the preparation thereof. The present invention covers the pyrazolo pyrimidinone based compounds that have been designed, synthesized and screened for PDE5 inhibitory activity and its PDE5 inhibitory potential is provided in this invention. These designer compounds have shown nanomolar potency when screened for PDE5 inhibitory activity and also shown better in vivo efficacy. These compounds can be used in the treatment of male erectile dysfunction or in the treatment of impotence.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: July 10, 2018
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sanghapal Damodhar Sawant, Lakshma Reddy Ginnereddy, Srinivas Mahesuni, Sajad Hussain Syed, Mohd Ishaq Dar, Amit Nargotra, Priya Mahajan, Ram Asrey Vishwakarma
  • Pyrazolopyrimidinones for the treatment of impotence and process for the preparation thereof
    Publication number: 20170066771
    Abstract: The present invention relates to Pyrazolopyrimidinone compounds as PDE5 inhibitors with better IC50 value, good in vivo efficacy and PK profile and a process for the preparation thereof. The present invention covers the pyrazolo pyrimidinone based compounds that have been designed, synthesized and screened for PDE5 inhibitory activity and its PDE5 inhibitory potential is provided in this invention. These designer compounds have shown nanomolar potency when screened for PDE5 inhibitory activity and also shown better in vivo efficacy. These compounds can be used in the treatment of male erectile dysfunction or in the treatment of impotence.
    Type: Application
    Filed: October 20, 2014
    Publication date: March 9, 2017
    Inventors: Sanghapal Damodhar SAWANT, Lakshma Reddy GINNEREDDY, Srinivas MAHESUNI, Sajad Hussain SYED, Mohd Ishaq DAR, Amit NARGOTRA, Priya MAHAJAN, Ram Asrey VISHWAKARMA