Patents by Inventor Sakae Aoyagi

Sakae Aoyagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of eliminating protective groups
    Patent number: 4977256
    Abstract: A method of deprotection which comprises reacting a compound having at least one of amino, hydroxyl, mercapto and carboxyl groups protected by a substituted or unsubstituted benzyloxycarbonyl group or by a substituted or unsubstituted benzyl group with zinc in a buffer, thereby splitting off the protective benzyloxycarbonyl or benzyl group.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: December 11, 1990
    Assignee: Lederle (Japan), Ltd.
    Inventors: Sakae Aoyagi, Takaaki Hayashi, Yasuhiro Kuramoto
  • Crystals of sodium cephemcarboxylate
    Patent number: 4692519
    Abstract: Novel crystals of sodium 7.beta.-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-3-[(1,2,3-th iadiazol-5-yl)thiomethyl] ceph-3-em-4-carboxylate showing characteristic peaks at interplanar spacings (d) of 9.3, 8.9, 5.3, 5.1, 4.4, 4.3 and 3.8 .ANG. in the powder X-ray diffraction pattern which are very stable and do not easily cause discoloration and decomposition.
    Type: Grant
    Filed: November 26, 1984
    Date of Patent: September 8, 1987
    Assignees: Lederle (Japan), Ltd., Takeda Chemical Industries, Ltd.
    Inventors: Kenzo Naito, Kazuo Tsukamura, Sakae Aoyagi