Patents by Inventor Sakayu Shimizu

Sakayu Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4269942
    Abstract: Acyl-CoA synthetase, having a high activity to C.sub.16 -C.sub.18 long chain fatty acids, is obtained by cultivating Pseudomonas aeruginosa IFO 3919. Pseudomonas aeruginosa IFO 3919 can produce acyl-CoA synthetase LCF-18 in large quantities, and the acyl-CoA synthetase LCF-18 produced by Pseudomonas aeruginosa IFO 3919 is very stable in storage.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: May 26, 1981
    Assignee: Amano Pharmaceutical Co. Ltd.
    Inventors: Hideaki Yamada, Sakayu Shimizu, Yoshiki Tani
  • Patent number: 4229538
    Abstract: Acyl-CoA synthetase, having a high activity to C.sub.16 -C.sub.18 long chain fatty acids, is obtained by culturing strains belonging to various genera. As is known, acyl-CoA synthetase, having a strong activity to C.sub.16 -C.sub.18 long chain fatty acids, is generally obtained from liver of rat; however, it has now been discovered that acyl-CoA synthetase can be obtained from microorganisms and this enzyme is called acyl-CoA synthetase LCF-18. By use of acyl-CoA synthetase LCF-18 of the present invention which has a high activity to C.sub.16 -C.sub.18 long chain fatty acids, serum non-esterified fatty acid of human beings can be accurately determined, and it is very useful for diagnosis of diabetes and so forth.
    Type: Grant
    Filed: April 9, 1979
    Date of Patent: October 21, 1980
    Assignee: Amano Pharmaceutical Co. Ltd.
    Inventors: Hideaki Yamada, Sakayu Shimizu, Yoshiki Tani