Patents by Inventor Saki HASEGAWA

Saki HASEGAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense nucleic acid inducing skipping of exon 51
    Patent number: 11781140
    Abstract: The present specification provides a drug that causes highly-efficient skipping of exon 51 in the human dystrophin gene. The present specification provides an antisense oligomer having an activity to induce skipping of exon 51 in the human dystrophin gene.
    Type: Grant
    Filed: August 25, 2022
    Date of Patent: October 10, 2023
    Assignees: NIPPON SHINYAKU CO., LTD., NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
    Inventors: Yu Honda, Kaname Muchima, Takahiro Fukui, Saki Hasegawa, Shin'ichi Takeda, Yoshitsugu Aoki
  • ANTISENSE NUCLEIC ACID INDUCING SKIPPING OF EXON 51
    Publication number: 20230140736
    Abstract: The present specification provides a drug that causes highly-efficient skipping of exon 51 in the human dystrophin gene. The present specification provides an antisense oligomer having an activity to induce skipping of exon 51 in the human dystrophin gene.
    Type: Application
    Filed: February 26, 2021
    Publication date: May 4, 2023
    Applicants: NIPPON SHINYAKU CO., LTD., NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
    Inventors: Yu HONDA, Kaname MUCHIMA, Takahiro FUKUI, Saki HASEGAWA, Shin'ichi TAKEDA, Yoshitsugu AOKI
  • ANTISENSE NUCLEIC ACID INDUCING SKIPPING OF EXON 51
    Publication number: 20230097387
    Abstract: The present specification provides a drug that causes highly-efficient skipping of exon 51 in the human dystrophin gene. The present specification provides an antisense oligomer having an activity to induce skipping of exon 51 in the human dystrophin gene.
    Type: Application
    Filed: August 25, 2022
    Publication date: March 30, 2023
    Applicants: NIPPON SHINYAKU CO., LTD., NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
    Inventors: Yu HONDA, Kaname MUCHIMA, Takahiro FUKUI, Saki HASEGAWA, Shin'ichi TAKEDA, Yoshitsugu AOKI
  • MODIFIED TCR AND PRODUCTION METHOD THEREFOR
    Publication number: 20220062341
    Abstract: An object of the invention is to provide a modified T-cell receptor (TCR) which does not cause the antigen responsiveness and which is capable of holding CD3 subunits on a cell membrane and causing the CD3 subunits to function. The invention is an invention related to a modified TCR comprising a first polypeptide and a second polypeptide, wherein the first polypeptide is a polypeptide which comprises a constant region of human TCR? or a fragment of the constant region and which does not comprise a variable region of human TCR?, and the second polypeptide is a polypeptide which comprises a constant region of human TCR? or a fragment of the constant region and which does not comprise a variable region of human TCR?.
    Type: Application
    Filed: December 26, 2019
    Publication date: March 3, 2022
    Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, KYOTO UNIVERSITY
    Inventors: Shinichiro TAKAYANAGI, Saki HASEGAWA, Ken FUKUMOTO, Atsushi KUNISATO, Satoshi NISHIKAWA, Shin KANEKO