Abstract: A potent short hairpin RNA (shRNA734) directed to human Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) improves the rate of gene-modified stem cell engraftment by a conditioning and in vivo selection strategy to confer resistance to a clinically available guanine analog antimetabolite, 6TG, for efficient positive selection of gene-modified stem cells. Uses for polynucleotides comprising the shRNA734 include methods for knocking down HPRT in a cell, for conferring resistance to a guanine analog antimetabolite in a cell, for producing selectable genetically modified cells, for selecting cells genetically modified with a gene of interest from a plurality of cells, for removing cells genetically modified with a gene of interest from a plurality of cells, and for treating a subject infected with HIV.

Abstract: A potent short hairpin RNA (shRNA734) directed to human Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) improves the rate of gene-modified stem cell engraftment by a conditioning and in vivo selection strategy to confer resistance to a clinically available guanine analog antimetabolite, 6TG, for efficient positive selection of gene-modified stem cells. Uses for polynucleotides comprising the shRNA734 include methods for knocking down HPRT in a cell, for conferring resistance to a guanine analog antimetabolite in a cell, for producing selectable genetically modified cells, for selecting cells genetically modified with a gene of interest from a plurality of cells, for removing cells genetically modified with a gene of interest from a plurality of cells, and for treating a subject infected with HIV.

Abstract: A potent short hairpin RNA (shRNA734) directed to human Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) improves the rate of gene-modified stem cell engraftment by a conditioning and in vivo selection strategy to confer resistance to a clinically available guanine analog antimetabolite, 6TG, for efficient positive selection of gene-modified stem cells. Uses for polynucleotides comprising the shRNA734 include methods for knocking down HPRT in a cell, for conferring resistance to a guanine analog antimetabolite in a cell, for producing selectable genetically modified cells, for selecting cells genetically modified with a gene of interest from a plurality of cells, for removing cells genetically modified with a gene of interest from a plurality of cells, and for treating a subject infected with HIV.

Abstract: A piece of mobile equipment has a display processor that displays an image and at least one icon on a screen, and a touch-sensitive device disposed on said screen. The display processor displays input information in accordance with an input operation to said touch-sensitive device, and removes the icon on the screen in accordance with the input operation.

Abstract: An endoscope is provided having an imaging sensor, a focusing lens, and an image processor. The imaging sensor converts an optical image to an output image signal. The focusing lens focuses on an object. The image processor calculates a contrast value based on the image signal while the focusing lens moves to focus on an object, and in the case where the image processor detects a region in which the amount of variation in the contrast value is within a predetermined range, while the focusing lens moves in a close range around a focusing point the image processor processes at least one output image in which either the image has been cropped to exclude the region, an ornament has been added to the region, or the region has been softened.

Abstract: An endoscope is provided having an imaging sensor, a focusing lens, and an image processor. The imaging sensor converts an optical image to an output image signal. The focusing lens focuses on an object. The image processor calculates a contrast value based on the image signal while the focusing lens moves to focus on an object, and in the case where the image processor detects a region in which the amount of variation in the contrast value is within a predetermined range, while the focusing lens moves in a close range around a focusing point the image processor processes at least one output image in which either the image has been cropped to exclude the region, an ornament has been added to the region, or the region has been softened.

Abstract: A display is provided having a screen and an operating part. The screen displays three or more selection items. The operating part is used to select two or more items among the selection items displayed on the screen. The screen displays and magnifies the two or more selection items that are selected.

Abstract: A piece of mobile equipment has a display processor that displays an image and at least one icon on a screen, and a touch-sensitive device disposed on said screen. The display processor displays input information in accordance with an input operation to said touch-sensitive device, and removes the icon on the screen in accordance with the input operation.

Abstract: An apparatus for photographing has a photographing processor that carries out a photographing process; a recording processor that records a photographic image; and a display processor that is capable of displaying a recorded photographic image. The display processor is also capable of displaying input information on an input information screen separately from the photographic image. The recording processor records the input information screen as an image. Then, the display processor displays the recorded input screen image.