Patents by Inventor Sakiko Hirose

Sakiko Hirose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING HSL PROTEIN HAVING IMPROVED CATALYTIC ACTIVITY FOR 2-OXOGLUTARIC ACID-DEPENDENTLY OXIDIZING 4-HPPD INHIBITOR
    Publication number: 20230374535
    Abstract: A method for producing an HSL protein with increased catalytic activity to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner is disclosed. A method for producing a plant with increased resistance to a 4-HPPD inhibitor using the method for producing the HSL protein is also disclosed. It has been revealed that, by mutating position 140 to a basic amino acid in an HSL protein, the catalytic activity of the protein to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner can be increased, and an activity of the protein to decompose the inhibitor can be increased.
    Type: Application
    Filed: July 7, 2023
    Publication date: November 23, 2023
    Applicants: National Agriculture and Food Research Organization, SDS BIOTECH K.K.
    Inventors: Yuzuru TOZAWA, Satomi Takei, Masahiro Oshima, Sakiko Hirose, Motoshige Kawata, Keisuke Sekino, Akihiko Yamazaki
  • Method for producing HSL protein having improved catalytic activity for 2-oxoglutaric acid-dependently oxidizing 4-HPPD inhibitor
    Patent number: 11746357
    Abstract: In order to provide: a method for producing an HSL protein with increased catalytic activity to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner; and a method for producing a plant with increased resistance to a 4-HPPD inhibitor using the method for producing the HSL protein, it has been revealed that, by mutating position 140 to a basic amino acid in an HSL protein, the catalytic activity of the protein to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner can be increased, and an activity of the protein to decompose the inhibitor can be increased.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: September 5, 2023
    Assignees: National Agriculture and Food Research Organization, SDS BIOTECH K.K.
    Inventors: Yuzuru Tozawa, Satomi Takei, Masahiro Oshima, Sakiko Hirose, Motoshige Kawata, Keisuke Sekino, Akihiko Yamazaki
  • METHOD FOR INTRODUCING GENOME EDITING ENZYME INTO PLANT CELL USING PLASMA
    Publication number: 20220403399
    Abstract: A method for introducing a genome editing enzyme into a plant cell includes: treating the cell with plasma; and then bringing the cell into contact with the genome editing enzyme in the presence of a di- or higher-valent metal cation.
    Type: Application
    Filed: November 12, 2020
    Publication date: December 22, 2022
    Applicant: National Agriculture and Food Research Organization
    Inventors: Ichiro MITSUHARA, Yuki YANAGAWA, Seiichi TOKI, Masaki IWAKAMI, Sakiko HIROSE, Etsuko KATOH, Akitoshi OKINO, Yuma SUENAGA, Shohei MORIYA, Yusuke IIJIMA
  • METHOD FOR PRODUCING HSL PROTEIN HAVING IMPROVED CATALYTIC ACTIVITY FOR 2-OXOGLUTARIC ACID-DEPENDENTLY OXIDIZING 4-HPPD INHIBITOR
    Publication number: 20200048315
    Abstract: In order to provide: a method for producing an HSL protein with increased catalytic activity to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner; and a method for producing a plant with increased resistance to a 4-HPPD inhibitor using the method for producing the HSL protein, it has been revealed that, by mutating position 140 to a basic amino acid in an HSL protein, the catalytic activity of the protein to oxidize a 4-HPPD inhibitor in a 2-oxoglutarate-dependent manner can be increased, and an activity of the protein to decompose the inhibitor can be increased.
    Type: Application
    Filed: February 9, 2018
    Publication date: February 13, 2020
    Applicants: National Agriculture and Food Research Organization, SDS Biotech K.K.
    Inventors: Yuzuru TOZAWA, Satomi TAKEI, Masahiro OSHIMA, Sakiko HIROSE, Motoshige KAWATA, Keisuke SEKINO, Akihiko YAMAZAKI
  • Plant having increased resistance or susceptibility to 4-HPPD inhibitor
    Patent number: 10544425
    Abstract: By a QTL analysis and so forth using 4-HPPD inhibitor-susceptible rice and 4-HPPD inhibitor-resistant rice, a hypothetical gene (HIS1 gene) of an iron/ascorbate-dependent oxidoreductase gene located on a short arm of chromosome 2 of rice has been identified as a 4-HPPD inhibitor-resistance gene. Further, it has also been revealed that a homologous gene (HSL1 gene) of the HIS1 gene is located on chromosome 6 of rice. Furthermore, it has been found out that utilizations of these genes make it possible to efficiently produce a plant having increased resistance or susceptibility to a 4-HPPD inhibitor and to efficiently determine whether a plant has resistance or susceptibility to a 4-HPPD inhibitor.
    Type: Grant
    Filed: December 26, 2011
    Date of Patent: January 28, 2020
    Assignees: Incorporated Administrative Agency National Agriculture Agriculture and Food Research Organization, TOYAMA PREFECTURE, SDS BIOTECH K.K.
    Inventors: Hiroshi Kato, Hideo Maeda, Yoshihiro Sunohara, Ikuo Ando, Masahiro Oshima, Motoshige Kawata, Hitoshi Yoshida, Sakiko Hirose, Makiko Kawagishi, Yojiro Taniguchi, Kazumasa Murata, Hiroaki Maeda, Yuji Yamada, Keisuke Sekino, Akihiko Yamazaki
  • PLANT HAVING INCREASED RESISTANCE OR SUSCEPTIBILITY TO 4-HPPD INHIBITOR
    Publication number: 20150047066
    Abstract: By a QTL analysis and so forth using 4-HPPD inhibitor-susceptible rice and 4-HPPD inhibitor-resistant rice, a hypothetical gene (HIS1 gene) of an iron/ascorbate-dependent oxidoreductase gene located on a short arm of chromosome 2 of rice has been identified as a 4-HPPD inhibitor-resistance gene. Further, it has also been revealed that a homologous gene (HSL1 gene) of the HIS1 gene is located on chromosome 6 of rice. Furthermore, it has been found out that utilizations of these genes make it possible to efficiently produce a plant having increased resistance or susceptibility to a 4-HPPD inhibitor and to efficiently determine whether a plant has resistance or susceptibility to a 4-HPPD inhibitor.
    Type: Application
    Filed: December 26, 2011
    Publication date: February 12, 2015
    Applicants: TOYAMA PREFECTURE, SDS BIOTECH K.K., Incorporated Adminstrative Agency National agriculture and Food Research Organization
    Inventors: Hiroshi Kato, Hideo Maeda, Yoshihiro Sunohara, Ikuo Ando, Masahiro Oshima, Motoshige Kawata, Hitoshi Yoshida, Sakiko Hirose, Makiko Kawagishi, Yojiro Taniguchi, Kazumasa Murata, Hiroaki Maeda, Yuji Yamada, Keisuke Sekino, Akihiko Yamazaki
  • Plants capable of metabolizing drugs and use thereof
    Patent number: 6613961
    Abstract: Transgenic plants capable of metabolizing drugs are constructed by introducing a drug-metabolizing P450 molecular species into plants. These plants are capable of detoxifying and metabolizing foreign compounds such as environmental loads and extrinsic endocrine disruptors including drugs, poisons, and agrochemicals. Thus, they are highly useful when applied to field crops, etc. Also, a method for selecting the drug-metabolizing P450 molecular species is provided.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: September 2, 2003
    Assignees: Bio-Oriented Technology Research Advancement Institution, National Institute of Agrobiological Sciences
    Inventors: Hideo Ohkawa, Yasunobu Ohkawa, Kenjirou Ozawa, Sakiko Hirose