Abstract: The present disclosure is directed to systems and techniques for providing immersive and interactive three-dimensional (3D) mapping data and visualizations thereof for emergency response incidents. In one example, the systems and techniques can obtain location information associated with an incident and obtain one or more portions of three-dimensional (3D) mapping data based on the location information associated with the incident. A 3D scene associated with the incident can be generated, wherein the 3D scene is generated based on the one or more portions of 3D mapping data. A first 3D view of the 3D scene can be generated, wherein the first 3D view includes one or more incident location indicators representing the location information of the incident relative to the 3D scene.

Abstract: The present invention relates to novel antitumor agents and pharmaceutically acceptable salts thereof, processes and intermediates for the manufacture of these novel constrained cyclic frameworks of general formula I and II, and medicaments containing such compounds.

Abstract: The invention relates to a single nucleotide polymorphism (SNP) of the nucleobase at base position 143470133 (rs13102150) of human chromosome 4 in the inositol polyphosphate 4-phosphatase type II gene (INPP4b gene) for the diagnosis or pre-diagnosis of multiple sclerosis or for determining the risk of contracting multiple sclerosis.