Abstract: Polypeptides of adeno-associated virus (AAV) that bind to AAV antibodies or block binding of AAV to mammalian cells are described. Derivatives of peptides can be less immunogenic, enhance binding to cells, render a virus tissue specific and so on. The nucleic acid sequence encoding those derivatives can be incorporated into a capsid encoding sequence to enable a virus to express such a derivative and be less immunogenic, have enhanced transduction efficiency or be tissue specific.

Abstract: The present invention provides anti-angiogenic compositions and methods, based on gene delivery vectors that include the coding sequence for an anti-angiogenic compound.

Abstract: Polypeptides of adeno-associated virus (AAV) that bind to AAV antibodies or block binding of AAV to mammalian cells are described. Derivatives of peptides can be less immunogenic, enhance binding to cells, render a virus tissue specific and so on. The nucleic acid sequence encoding those derivatives can be incorporated into a capsid encoding sequence to enable a virus to express such a derivative and be less immunogenic, have enhanced transduction efficiency or be tissue specific.

Abstract: Polypeptides of adeno-associated virus (AAV) that bind to AAV antibodies or block binding of AAV to mammalian cells are described. Derivatives of peptides can be less immunogenic, enhance binding to cells, render a virus tissue specific and so on. The nucleic acid sequence encoding those derivatives can be incorporated into a capsid encoding sequence to enable a virus to express such a derivative and be less immunogenic, have enhanced transduction efficiency or be tissue specific.

Abstract: A computer-implemented education and procurement system, method, and program storage medium for use in learning about scientific procedures and procuring products related thereto. According to one aspect of the invention, the system may include a graphical user interface (GUI) configured to display (a) a user-selected tutorial having a description of a scientific procedure, (b) one or more requirements for the scientific procedure, and (c) product information regarding one or more commercially available products that may be used to satisfy each requirement. According to another aspect of the invention, the method may include, receiving a command from a user to display a user-selected tutorial containing information related to a scientific procedure, displaying the user-selected tutorial, and on the same screen as the tutorial, displaying product information corresponding to one or more commercially available products required to conduct the scientific procedure.

Abstract: A computer-based educational system and method for presenting information. The system may include among others a content pane configured to present a presentation of a series of slides, and a progress control configured to adjust a user's progress through a currently displayed slide, a progress indicator configured to indicate a user's time-based viewing progress through a slide, a presentation, or a series of presentations, and/or a link to a text transcript of any associated voiceover narration.