Patents by Inventor Sally Anderson
Sally Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210008557Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.Type: ApplicationFiled: December 21, 2018Publication date: January 14, 2021Applicants: Oxford Nanopore Technologies Ltd., Sharp Life Science (EU) LtdInventors: Matthew HOLDEN, James WHITE, Andrew John HERON, James Anthony CLARKE, Jason Robert HYDE, Benjamin James HADWEN, Sally ANDERSON
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Publication number: 20200261911Abstract: A method of operating an electrowetting on dielectric (EWOD) device performs microfluidic diffusion separation.Type: ApplicationFiled: February 15, 2019Publication date: August 20, 2020Inventors: Christopher James Brown, Sally Anderson, Adam Christopher Wilson
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Patent number: 10695761Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.Type: GrantFiled: May 30, 2017Date of Patent: June 30, 2020Assignee: Sharp Life Science (EU) LimitedInventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
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Publication number: 20200101460Abstract: An electrowetting on dielectric (EWOD) device includes an EWOD device array that applies electrowetting forces and contains a non-polar fluid. A barrier droplet configuration is formed using electrowetting forces to obstruct migration of a species from a first area of the EWOD device array to a protected area of the EWOD device array. A method of operating the EWOD device includes the steps of: dispensing a source droplet into a first area of the EWOD device array, the source droplet containing a migrating species, wherein the EWOD device array includes a second area to be protected from the migrating species; and forming a barrier droplet configuration positioned between the first area and the second area of the EWOD device array that obstructs a migration pathway of the migrating species between the first area and the second area.Type: ApplicationFiled: October 1, 2018Publication date: April 2, 2020Inventors: Adam Christopher Wilson, Sally Anderson, Peter Neil Taylor, Campbell Donald Brown, Pamela Ann Dothie, Laura Huang
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Publication number: 20200061620Abstract: An electrowetting on dielectric (EWOD) device and a related method of performing a digital biological assay in an EWOD device are described.Type: ApplicationFiled: August 21, 2018Publication date: February 27, 2020Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
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Patent number: 10571426Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.Type: GrantFiled: August 13, 2018Date of Patent: February 25, 2020Assignee: Sharp Life Science (EU) LimitedInventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, Sally Anderson
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Publication number: 20190388894Abstract: A method of performing a digital quantification of a species in an electrowetting on dielectric (EWOD) device comprising the steps of: inputting a sample volume into the EWOD device; inputting a diluent volume into the EWOD device; performing an electrowetting operation to generate a first sample droplet from the sample volume; performing an amplification process on the first sample droplet within the EWOD device; measuring a turn-on value for the sample droplet; comparing the measured turn-on value of the sample droplet to a target turn-on value for digital quantification; calculating a dilution factor based on the comparison of the measured turn-on value of the sample droplet to the target turn-on value; performing an electrowetting operation to extract a second sample droplet from the sample volume; performing an electrowetting operation to dilute the second sample droplet with the diluent volume in accordance with the dilution factor to form a diluted second sample droplet; and performing a digital quantiType: ApplicationFiled: June 21, 2018Publication date: December 26, 2019Inventors: Pamela Ann Dothie, Sally Anderson, Philip Mark Shryane Roberts
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Publication number: 20190004009Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.Type: ApplicationFiled: August 13, 2018Publication date: January 3, 2019Inventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, Sally Anderson
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Publication number: 20180345279Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.Type: ApplicationFiled: May 30, 2017Publication date: December 6, 2018Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
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Patent number: 10082481Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.Type: GrantFiled: July 7, 2016Date of Patent: September 25, 2018Assignee: Sharp Life Science (EU) LimitedInventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, SAlly Anderson
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Publication number: 20180157756Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.Type: ApplicationFiled: February 5, 2018Publication date: June 7, 2018Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson
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Patent number: 9886506Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.Type: GrantFiled: June 19, 2009Date of Patent: February 6, 2018Assignee: SNS Conference CorporationInventors: Mark R. Anderson, Scott Schramke, Sally Anderson
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Publication number: 20180011053Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.Type: ApplicationFiled: July 7, 2016Publication date: January 11, 2018Inventors: Benjamin James HADWEN, Campbell Donald BROWN, Christopher James BROWN, Gregory GAY, Sally ANDERSON
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Publication number: 20100153285Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.Type: ApplicationFiled: June 19, 2009Publication date: June 17, 2010Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson
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Publication number: 20100105567Abstract: The current invention relates to a multimeric capture agent for binding a ligand, the multimeric capture agent comprising at least first and second peptide chains, wherein said first and second peptide chains each comprise a chain of 2 to 50 amino acids, each of said amino acids being substantially enantiomerically pure, and wherein said at least first and second peptide chains are covalently linked.Type: ApplicationFiled: December 19, 2006Publication date: April 29, 2010Inventors: Michael A. Reeve, Sally Anderson
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Publication number: 20090312192Abstract: The current invention relates to a method of functionalising a substrate comprising immobilising at least one multimeric peptide on the substrate, wherein, the at least one multimeric peptide comprises at least first and second peptide chains, the first peptide chain comprising at least one hydrophobic amino acid residue and at least one functionalising moiety, wherein the at least one hydrophobic amino acid residue and at least one functionalising moiety are positioned in the peptide primary structure so as to result in a hydrophobic face, and a substantially non hydrophobic face comprising the functionalising moiety, and wherein, contacting the peptide with the substrate causes the peptide to be immobilised thereon.Type: ApplicationFiled: December 19, 2006Publication date: December 17, 2009Inventors: Michael A. Reeve, Sally Anderson
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Publication number: 20090192048Abstract: The current invention relates to a method of fabricating a multimeric capture agent for binding a ligand, the capture agent comprising at least first and second monomers units, the first monomer unit further comprising a first ligand-binding moiety, a first reactive group and an attachment moiety, the second monomer unit further comprising a second ligand-binding moiety, and a second reactive group, wherein the reactive groups may be the same or different for each monomer unit, the method comprising the steps of; a) reacting the first monomer unit with the second monomer unit such that reactive groups present on the monomer units react to form a multimeric capture agent. b) immobilising the first monomer unit on a substrate via the attachment moiety, wherein, step a) can be performed before, simultaneously with, or subsequently to step b).Type: ApplicationFiled: December 19, 2006Publication date: July 30, 2009Inventors: Michael A Reeve, Sally Anderson
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Publication number: 20030105343Abstract: There is disclosed a method of preparing a branched benzofuran compound comprising a core moiety which contains at least one aromatic ring and which has at least three substituted or unsubstituted benzofuran groups covalently linked thereto.Type: ApplicationFiled: September 25, 2002Publication date: June 5, 2003Inventors: Peter Neil Taylor, Sally Anderson, Christopher James Booth, Geraldine Laura Ballantyne Verschoor
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Patent number: 6555840Abstract: A charge-transport structure, e g an opto-electronic structure such an electroluminescent device is manufactured by forming a uniform first charge-transport (eg electron-transport) polymer layer on a substrate. Low molar mass dyes in a solvent are ink-jet printed onto the exposed surface of the first layer to form a multicolor pattern, and the dyes are allowed to diffuse into the layer to form charge-recombination/emitter regions within the layer. Excess dyes are washed away from the surface and then a uniform second charge-transport (eg hole-transport) polymer layer is formed on the resultant smooth surface of the first layer over the tops of the regions. Finally, electrodes are deposited on the top of the second layer in registration with the regions. Photovoltaic structures and organic transistors are also disclosed.Type: GrantFiled: February 15, 2000Date of Patent: April 29, 2003Assignee: Sharp Kabushiki KaishaInventors: Andrew James Hudson, Sally Anderson, Michael Stuart Weaver, Craig Tombling
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Patent number: 6437123Abstract: A compound of the present invention is a triazine compound of the general formula: Ar, Ar′ and Ar″ are aromatic moieties which are conjugated to the triazine core and are the same or different. Each of R1, R1′, R1″ to Rn, Rn′, Rn″, which may be the same or different, is an elongated flexible, at least partly aliphatic chain such as to impart liquid-crystalline or columnar crystalline properties to the compound or its mixtures. —(R1, . . . , Rn), —(R1′, . . . , Rn′) and —(R1″, . . . , Rn″) indicate that there are up to n, n′ and n″ substituent groups R on respective Ar, Ar′, Ar″ moieties, where n, n′ and n″ are integers which do not exceed a number of available substituent positions on the respective Ar, Ar′, Ar″ moieties.Type: GrantFiled: April 27, 1999Date of Patent: August 20, 2002Assignee: Sharp Kabushiki KaishaInventors: Harald Reinhart Bock, Sally Anderson, Yoshimasa Fujita, Andrew James Hudson, Judy Megan Rorison, Michael Stuart Weaver