Patents by Inventor Sally Anderson

Sally Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11219898
    Abstract: A method of operating an electrowetting on dielectric (EWOD) device performs microfluidic diffusion separation.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: January 11, 2022
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Christopher James Brown, Sally Anderson, Adam Christopher Wilson
  • Patent number: 11207686
    Abstract: An EWOD device and a related method of performing a digital biological assay are described that employs two volume measurements for enhanced assay determination. The method includes partitioning a sample reservoir and measuring the volume of each partition; initiating a biological assay wherein the biological assay includes measuring a partition property and a volume of each partition in real time as part of determining a concentration of the product substance in each partition based on the measured partition property and volume; and categorizing the partitions by a number of biological entities contained in each partition from which the number of biological entities may be calculated, which in turn may be used to calculate the total number of biological entities or concentration in the sample reservoir. The method further may include an enhanced partitioning process that minimizes variation in the volume of the partitions.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: December 28, 2021
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
  • Patent number: 11198130
    Abstract: A method of digital quantification of a species in an EWOD device includes inputting a sample volume and a diluent volume into the EWOD device; performing an electrowetting operation to generate a first sample droplet from the sample volume; performing an amplification process on the first sample droplet and measuring a turn-on value for the sample droplet; comparing the measured turn-on value to a target turn-on value for digital quantification; calculating a dilution factor based on the comparison of the measured and target turn-on values; performing an electrowetting operation to extract a second sample droplet from the sample volume; performing an electrowetting operation to dilute the second sample droplet with the diluent volume by the dilution factor to form a diluted second sample droplet; and performing a digital quantification on the diluted second sample droplet to quantify an initial concentration of the species in the sample volume.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: December 14, 2021
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Pamela Ann Dothie, Sally Anderson, Philip Mark Shryane Roberts
  • Patent number: 11093559
    Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: August 17, 2021
    Assignee: SNS Conference Corporation
    Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson
  • Publication number: 20210162417
    Abstract: A microfluidic system and related methods of operating an electrowetting on dielectric (EWOD) device operate to concentrate particles within a liquid droplet dispensed onto an element array of the EWOD device. The method includes the steps of providing a non-polar liquid onto the element array of the EWOD device; providing a polar liquid droplet onto the element array of the EWOD device within the non-polar liquid, wherein the polar liquid droplet includes particles; and applying an actuation cycle comprising a plurality of actuation patterns, wherein at least one of the actuation patterns includes actuating one or more array element electrodes within a perimeter of the polar liquid droplet, and the particles migrate within the polar liquid droplet to become concentrated within a portion of the liquid droplet at one or more array element electrodes corresponding to one of the plurality of actuation patterns.
    Type: Application
    Filed: December 3, 2019
    Publication date: June 3, 2021
    Inventors: Simon M. Bryant, Benjamin J. Hadwen, Christopher J. Brown, Sally Anderson
  • Patent number: 10913067
    Abstract: An electrowetting on dielectric (EWOD) device includes an EWOD device array that applies electrowetting forces and contains a non-polar fluid. A barrier droplet configuration is formed using electrowetting forces to obstruct migration of a species from a first area of the EWOD device array to a protected area of the EWOD device array. A method of operating the EWOD device includes the steps of: dispensing a source droplet into a first area of the EWOD device array, the source droplet containing a migrating species, wherein the EWOD device array includes a second area to be protected from the migrating species; and forming a barrier droplet configuration positioned between the first area and the second area of the EWOD device array that obstructs a migration pathway of the migrating species between the first area and the second area.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: February 9, 2021
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Adam Christopher Wilson, Sally Anderson, Peter Neil Taylor, Campbell Donald Brown, Pamela Ann Dothie, Laura Huang
  • Publication number: 20210008557
    Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.
    Type: Application
    Filed: December 21, 2018
    Publication date: January 14, 2021
    Applicants: Oxford Nanopore Technologies Ltd., Sharp Life Science (EU) Ltd
    Inventors: Matthew HOLDEN, James WHITE, Andrew John HERON, James Anthony CLARKE, Jason Robert HYDE, Benjamin James HADWEN, Sally ANDERSON
  • Publication number: 20200261911
    Abstract: A method of operating an electrowetting on dielectric (EWOD) device performs microfluidic diffusion separation.
    Type: Application
    Filed: February 15, 2019
    Publication date: August 20, 2020
    Inventors: Christopher James Brown, Sally Anderson, Adam Christopher Wilson
  • Patent number: 10695761
    Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: June 30, 2020
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
  • Publication number: 20200101460
    Abstract: An electrowetting on dielectric (EWOD) device includes an EWOD device array that applies electrowetting forces and contains a non-polar fluid. A barrier droplet configuration is formed using electrowetting forces to obstruct migration of a species from a first area of the EWOD device array to a protected area of the EWOD device array. A method of operating the EWOD device includes the steps of: dispensing a source droplet into a first area of the EWOD device array, the source droplet containing a migrating species, wherein the EWOD device array includes a second area to be protected from the migrating species; and forming a barrier droplet configuration positioned between the first area and the second area of the EWOD device array that obstructs a migration pathway of the migrating species between the first area and the second area.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 2, 2020
    Inventors: Adam Christopher Wilson, Sally Anderson, Peter Neil Taylor, Campbell Donald Brown, Pamela Ann Dothie, Laura Huang
  • Publication number: 20200061620
    Abstract: An electrowetting on dielectric (EWOD) device and a related method of performing a digital biological assay in an EWOD device are described.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 27, 2020
    Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
  • Patent number: 10571426
    Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: February 25, 2020
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, Sally Anderson
  • Publication number: 20190388894
    Abstract: A method of performing a digital quantification of a species in an electrowetting on dielectric (EWOD) device comprising the steps of: inputting a sample volume into the EWOD device; inputting a diluent volume into the EWOD device; performing an electrowetting operation to generate a first sample droplet from the sample volume; performing an amplification process on the first sample droplet within the EWOD device; measuring a turn-on value for the sample droplet; comparing the measured turn-on value of the sample droplet to a target turn-on value for digital quantification; calculating a dilution factor based on the comparison of the measured turn-on value of the sample droplet to the target turn-on value; performing an electrowetting operation to extract a second sample droplet from the sample volume; performing an electrowetting operation to dilute the second sample droplet with the diluent volume in accordance with the dilution factor to form a diluted second sample droplet; and performing a digital quanti
    Type: Application
    Filed: June 21, 2018
    Publication date: December 26, 2019
    Inventors: Pamela Ann Dothie, Sally Anderson, Philip Mark Shryane Roberts
  • Publication number: 20190004009
    Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.
    Type: Application
    Filed: August 13, 2018
    Publication date: January 3, 2019
    Inventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, Sally Anderson
  • Publication number: 20180345279
    Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.
    Type: Application
    Filed: May 30, 2017
    Publication date: December 6, 2018
    Inventors: Sally Anderson, Pamela Ann Dothie, Philip Mark Shryane Roberts
  • Patent number: 10082481
    Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: September 25, 2018
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, SAlly Anderson
  • Publication number: 20180157756
    Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.
    Type: Application
    Filed: February 5, 2018
    Publication date: June 7, 2018
    Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson
  • Patent number: 9886506
    Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: February 6, 2018
    Assignee: SNS Conference Corporation
    Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson
  • Publication number: 20180011053
    Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.
    Type: Application
    Filed: July 7, 2016
    Publication date: January 11, 2018
    Inventors: Benjamin James HADWEN, Campbell Donald BROWN, Christopher James BROWN, Gregory GAY, Sally ANDERSON
  • Publication number: 20100153285
    Abstract: The integration of news about members of a group into symmetrical group communications is described. Group members are delivered news items and information regarding members of the group, and are able to communicate with other members of the group in response to the news items. One embodiment dynamically generates aggregated RSS news feeds for a group of people or entities and correlates that aggregated data with biographical information, audio, and video media to provide rich information about the relevant parties to the news story. The embodiment also provides the capability of transmitting email or other electronic messages to the parties in the news story to facilitate two-way communication while maintaining the group members' privacy and anonymity.
    Type: Application
    Filed: June 19, 2009
    Publication date: June 17, 2010
    Inventors: Mark R. Anderson, Scott Schramke, Sally Anderson