Abstract: An aerosol provision system for generating aerosol from an aerosol-generating material. The system comprises an article comprising the aerosol-generating material and an aerosol provision device configured to engage with the article and to enable generation of aerosol from the aerosol-generating material. The system further includes detection circuitry for detecting when the article is engaged and/or disengaged with the aerosol provision device, and control circuitry for controlling operation of the aerosol provision device. The control circuitry is configured to switch the aerosol provision device from a first operating mode to a second operating mode when the control circuitry determines the article has been engaged with and/or disengaged with the aerosol provision device a plurality of times.

Abstract: An aerosol-generating article comprising an aerosolizable material comprising nicotine; a solid basic material; and a wetting agent; wherein in use, the wetting agent is combined with the solid basic material and the aerosolizable material on actuation of a combining mechanism by a user.

Abstract: A device for generating an inhalable medium, the device comprising: a container retaining a first volatilizable material; a heater for volatilising the first volatilizable material held in the container; a chamber containing aerosolizable material comprising nicotine; a reservoir containing a basic solution; and an outlet; the arrangement being such that in use, the basic solution is released from the reservoir and enters the chamber containing the aerosolizable material, and the first volatilizable material is volatilized by the heater to form a vapor and/or an aerosol, which passes through the chamber containing aerosolizable material and entrains one or more constituents of the aerosolizable material, thereby forming an inhalable medium which passes through the outlet.

Abstract: A device for generating an inhalable medium, the device comprising a container for holding a first aerosolizablea material; a heater for volatilising the first aerosolizable material held in the container; a chamber for holding a second aerosolizable material, wherein internal surfaces of the chamber comprise a BPA-free, BPS-free copolyester plastic; and an outlet; wherein the device is configured such that in use, an inhalable medium is generated and passes through the outlet, the inhalable medium comprising components of the first and second aerosolizable materials in the form of a vapor and/or an aerosol.

Abstract: Embodiments provides treated tobacco material having a pH of at least 9 and a moisture content of no more than 20% based on the dry weight of the tobacco. Embodiments also provide a process for treating tobacco material to increase its pH to at least 9, the process comprising applying a basic solution to the tobacco material to be treated, and drying the material to produce a treated tobacco material with a moisture content of no more than 20%. Embodiments also provide devices comprising the treated tobacco material, and uses of the treated tobacco material.

Abstract: A process is provided for the preparation and/or treatment of a tobacco extract. The process comprises the treatment of a tobacco extract by centrifugation and microfiltration so that it is suitable for administration to a human.

Abstract: Embodiments provides treated tobacco material having a pH of at least 9 and a moisture content of no more than 20% based on the dry weight of the tobacco. Embodiments also provide a process for treating tobacco material to increase its pH to at least 9, the process comprising applying a basic solution to the tobacco material to be treated, and drying the material to produce a treated tobacco material with a moisture content of no more than 20%. Embodiments also provide devices comprising the treated tobacco material, and uses of the treated tobacco material.

Abstract: A process is provided for the preparation and/or treatment of a tobacco extract. The process comprises the treatment of a tobacco extract by centrifugation and microfiltration so that it is suitable for administration to a human.