Patents by Inventor Sally Gut Ruggeri

Sally Gut Ruggeri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation Of A Pyrimidinyl-3,8-Diazabicyclo[3.2.1]Octanylmethanone Derivative And Salt Thereof
    Publication number: 20230265101
    Abstract: Methods for preparing ((S)-2,2-difluorocyclopropyl)-((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]-octan-8-yl)methanone and intermediates used in the processes of preparation thereof.
    Type: Application
    Filed: June 30, 2021
    Publication date: August 24, 2023
    Applicant: PFIZER INC.
    Inventors: Adam Edward GOETZ, Sally Gut RUGGERI, Robert Alan SINGER
  • Pyrrolo[2,3-d]pyrimidine derivatives: their intermediates and synthesis
    Patent number: 8309716
    Abstract: This invention relates to methods and intermediates useful for the synthesis of pyrrolo[2,3-d]pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: November 13, 2012
    Assignee: Pfizer Inc.
    Inventors: Sally Gut Ruggeri, Joel M Hawkins, Teresa M Makowski, Jennifer L Rutherford, Frank J Urban
  • PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES: THEIR INTERMEDIATES AND SYNTHESIS
    Publication number: 20120259115
    Abstract: This invention relates to methods and intermediates useful for the synthesis of pyrrolo [2,3-d] pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.
    Type: Application
    Filed: June 20, 2012
    Publication date: October 11, 2012
    Applicant: PFIZER INC.
    Inventors: Sally Gut Ruggeri, Joel M. Hawkins, Teresa M. Makowski, Jennifer L. Rutherford, Frank J. Urban
  • Pyrrolo[2,3-d]pyrimidine derivatives; their intermediates and synthesis
    Patent number: 8232394
    Abstract: This invention relates to methods and intermediates useful for the synthesis of pyrrolo[2,3-d]pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: July 31, 2012
    Assignee: Pfizer Inc.
    Inventors: Sally Gut Ruggeri, Joel M. Hawkins, Teresa M. Makowski, Jennifer L. Rutherford, Frank J. Urban
  • Pyrrolo[2,3-d]Pyrimidine Derivatives; Their Intermediates and Synthesis
    Publication number: 20110288297
    Abstract: This invention relates to methods and intermediates useful for the synthesis of pyrrolo[2,3-d]pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.
    Type: Application
    Filed: July 17, 2006
    Publication date: November 24, 2011
    Applicant: Pfizer, Inc.
    Inventors: Sally Gut Ruggeri, Joel M. Hawkins, Teresa M. Makowski, Jennifer L. Rutherford, Frank J. Urban
  • Process for converting 2,4-dichloropyridines into 2-aryloxy-4-chloropyridines
    Patent number: 6316631
    Abstract: This invention relates to a process for converting 2,4-dichloropyridines into 2-aryloxy-4-chloropyridines, comprising reacting a compound of formula (I), wherein R1 is (C1-C4)alkyl; R2 is methyl or ethyl; and R3, R4 and R5 are selected, independently, from (C1-C4)alkyl and (C1-C4)alkoxy; or a pharmaceutically acceptable salt thereof; comprising reacting a compound of formula (II), wherein R1 and R2 are defined as above, with a compound of formula (III), wherein R3, R4 and R5 are defined as above, in the presence of a base that is capable of deprotonating the compound of formula (III), optionally in the presence of an organometallic halide or oxide and a suitable solvent, and then optionally converting the resulting compound of formula (I) into a pharmaceutically acceptable salt of such compound.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: November 13, 2001
    Assignee: Pfizer Inc.
    Inventors: Yuhpyng L. Chen, Sally Gut Ruggeri