Patents by Inventor Sally MacKenzie

Sally MacKenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10913986
    Abstract: A computer-implemented method of preparing a set of differentially informative methylated positions (DIMPs) or differentially informative methylated regions (DIMRs) from a sample methylome of an animal or plant having a phenotypic characteristic different from a wild-type of the same species of animal or plant, and the characteristic is associate with differences in methylation of the genome, comprises: providing a computer with the sample methylome, and a reference methylome of the wild-type of the same species of animal or plant; calculating with the computer a divergence between a plurality of cytosine positions of the sample methylome and the reference methylome; and selecting with the computer a set of DIMPs or DIMRs. Each DIMP or DIMR is selected based on an approximation of the energy required to produce the divergence between methylation levels of the plurality of cytosine positions of the sample methylome as compared to the wild-type methylome.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: February 9, 2021
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Sally A. Mackenzie, Robersy Sanchez
  • Publication number: 20210017534
    Abstract: The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided.
    Type: Application
    Filed: August 10, 2020
    Publication date: January 21, 2021
    Inventors: Sally Mackenzie, Michael Fromm, Kamaldeep Virdi, Yashitola Wamboldt
  • Patent number: 10767188
    Abstract: The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: September 8, 2020
    Assignee: NUTECH VENTURES
    Inventors: Sally Mackenzie, Michael Fromm, Kamaldeep Virdi, Yashitola Wamboldt
  • Patent number: 10364438
    Abstract: The present disclosure provides methods for obtaining plants that exhibit useful traits or that are useful for plant breeding by suppression of plastidic MSH1 in the presence of mitochondrial-targeted MSH1 in plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for suppression of plastidic MSH1 in the presence of mitochondrial-targeted MSH1 are also provided.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: July 30, 2019
    Assignee: NUTECH VENTURES
    Inventors: Sally A. Mackenzie, Kamaldeep Virdi
  • Publication number: 20170218463
    Abstract: A computer-implemented method of preparing a set of differentially informative methylated positions (DIMPs) or differentially informative methylated regions (DIMRs) from a sample methylome of an animal or plant having a phenotypic characteristic different from a wild-type of the same species of animal or plant, and the characteristic is associate with differences in methylation of the genome, comprises: providing a computer with the sample methylome, and a reference methylome of the wild-type of the same species of animal or plant; calculating with the computer a divergence between a plurality of cytosine positions of the sample methylome and the reference methylome; and selecting with the computer a set of DIMPs or DIMRs. Each DIMP or DIMR is selected based on an approximation of the energy required to produce the divergence between methylation levels of the plurality of cytosine positions of the sample methylome as compared to the wild-type methylome.
    Type: Application
    Filed: February 1, 2017
    Publication date: August 3, 2017
    Inventors: Sally A. Mackenzie, Robersy Sanchez
  • Publication number: 20160192608
    Abstract: The present invention provides methods for obtaining plants that exhibit useful traits by producing double haploids of plants with epigenetic modifications initiated in a parental line by suppression of MSH1. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided.
    Type: Application
    Filed: January 19, 2015
    Publication date: July 7, 2016
    Inventors: Michael E. Fromm, Sally A. Mackenzie
  • Publication number: 20150113679
    Abstract: The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided.
    Type: Application
    Filed: September 24, 2014
    Publication date: April 23, 2015
    Inventors: Sally Mackenzie, Michael Fromm, Kamaldeep Virdi, Yashitola Wamboldt
  • Publication number: 20150052630
    Abstract: Methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plants are provided. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 19, 2015
    Inventors: Sally Mackenzie, Michael Fromm, Kamaldeep Virdi, Yashitola Wamboldt, Jiantao Yu, Mon-Ray Shao
  • Patent number: 7223901
    Abstract: The subject invention relates to nematode responsive domains obtained from soybean promoters for phosphoribosylformylglycinamidine ribonucleotide (FGAM) synthase paralogs. The nematode responsive domains can be used in promoters that are linked to heterologous DNA. Such constructs can be expressed in transfected or transformed soybean and used in the control of nematode infection of soybean.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: May 29, 2007
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Sally MacKenzie, Zarir Vaghchhipawala
  • Publication number: 20060248613
    Abstract: Plant MSH1 polynucleotides and polypeptides are described. Also described are methods for the use and modulation of such MSH1 polynucleotides and polypeptides.
    Type: Application
    Filed: April 24, 2006
    Publication date: November 2, 2006
    Inventors: Sally Mackenzie, Ricardo Abdelnoor
  • Publication number: 20060248614
    Abstract: Plant MSH1 polynucleotides and polypeptides are described. Also described are methods for the use and modulation of such MSH1 polynucleotides and polypeptides.
    Type: Application
    Filed: April 27, 2006
    Publication date: November 2, 2006
    Inventors: Sally Mackenzie, Ricardo Abdelnoor
  • Publication number: 20050262585
    Abstract: The subject invention relates to nematode responsive domains obtained from soybean promoters for phosphoribosylformylglycinamidine ribonucleotide (FGAM) synthase paralogs. The nematode responsive domains can be used in promoters that are linked to heterologous DNA. Such constructs can be expressed in transfected or transformed soybean and used in the control of nematode infection of soybean.
    Type: Application
    Filed: March 28, 2005
    Publication date: November 24, 2005
    Inventors: Sally MacKenzie, Zarir Vaghchhipawala
  • Publication number: 20040210962
    Abstract: Plant MSH1 polynucleotides and polypeptides are described. Also described are methods for the use and modulation of such MSH1 polynucleotides and polypeptides.
    Type: Application
    Filed: March 22, 2004
    Publication date: October 21, 2004
    Applicant: The Board of Regents of the University of Nebraska
    Inventors: Sally Mackenzie, Ricardo Vilela Abdelnoor