Patents by Inventor Sally Temple Stern

Sally Temple Stern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9994826
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 12, 2018
    Assignee: Regenerative Research Foundation
    Inventors: Sally Temple Stern, Jeffrey Stern
  • Publication number: 20170082611
    Abstract: Methods for inhibiting epithelial to mesenchymal transition (EMT) in epithelial cells are disclosed. The methods can include contacting epithelial cells, such as retinal pigment epithelial cells or breast epithelial cells, with an inhibitor of the forkhead box s1 (FOXS1) signaling pathway.
    Type: Application
    Filed: September 21, 2016
    Publication date: March 23, 2017
    Inventors: Jeffrey Stern, Sally Temple Stern, Timothy Blenkinsop
  • Publication number: 20150148383
    Abstract: Described herein are treatment methods involving the administration of nicotinamide, which has been discovered to stabilize the normal phenotype of retinal pigment epithelial cells and to prevent retinal pigment epithelial cell proliferation. Diseases and disorders that can be treated according to the methods disclosed herein include, e.g., macular pucker, proliferative vitreoretinopathy, preretinal fibrosis, vitreomacular traction, tractional retinal detachment, and phthsis bulbi, cystoid macular edema (CME) arising from intraocular inflammation due to uveitis, vasculitis, trauma, surgery, and collagen vascular disease (e.g., Behcets disease or sarcoidosis), and age related macular degeneration.
    Type: Application
    Filed: November 21, 2014
    Publication date: May 28, 2015
    Inventors: Jeffrey Stern, Sally Temple Stern, Timothy Blenkinsop
  • Publication number: 20150064784
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Application
    Filed: September 12, 2014
    Publication date: March 5, 2015
    Inventors: Sally Temple Stern, Jeffrey Stern
  • Publication number: 20150051212
    Abstract: Described herein are methods for inhibiting drusen.
    Type: Application
    Filed: March 13, 2013
    Publication date: February 19, 2015
    Inventors: Sally Temple Stern, Jeffrey Stern
  • Patent number: 8841123
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: September 23, 2014
    Assignee: Regenerative Research Foundation
    Inventors: Jeffrey Stern, Sally Temple Stern
  • Publication number: 20140227232
    Abstract: The present invention relates to treatment methods and methods for sustained delivery of one or more exogenous factors to desired nervous system sites. In certain embodiments, the invention relates to the use of biodegradable microspheres to deliver exogenous factors, such as the morphogenic factor, sonic hedgehog (Shh), to the site of spinal cord injury. In certain embodiments, the Shh-releasing microspheres are administered together with stem cells, which may be spinal cord neural stem cells. In certain embodiments, the invention relates to regrowth of neural cells in both the central and peripheral nervous systems.
    Type: Application
    Filed: November 12, 2013
    Publication date: August 14, 2014
    Applicants: ALBANY MEDICAL COLLEGE, REGENERATIVE RESEARCH FOUNDATION
    Inventors: Sally Temple Stern, Natalia Lowry, Jeffrey Stern, Susan K. Goderie
  • Publication number: 20130337562
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 19, 2013
    Applicant: Regenerative Research Foundation
    Inventors: Jeffrey Stern, Sally Temple Stern
  • Patent number: 8481308
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: July 9, 2013
    Assignee: Regenerative Research Foundation
    Inventors: Jeffrey Stern, Sally Temple Stern
  • Publication number: 20120101024
    Abstract: Methods and compositions for differentiating mammalian stem and progenitor cells are provided. More particularly, methods and compositions for obtaining neural cells from human embryonic stem cells are provided.
    Type: Application
    Filed: October 26, 2011
    Publication date: April 26, 2012
    Applicant: REGENERATIVE RESEARCH FOUNDATION
    Inventors: Sally Temple Stern, Christopher A. Fasano
  • Publication number: 20120003736
    Abstract: Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state.
    Type: Application
    Filed: July 1, 2011
    Publication date: January 5, 2012
    Applicant: Regenerative Research Foundation
    Inventors: Jeffrey Stern, Sally Temple Stern