Patents by Inventor Salvador E. Moncada

Salvador E. Moncada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide synthase inhibitors
    Patent number: 5585402
    Abstract: The present invention discloses a method for inhibiting tissue damage in mammals caused by pathological NO production, which comprises administering an effective tissue damage inhibition amount of a NO synthase inhibitor to said mammal. Preferably the NO synthase inhibitor is L-NMMA.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: December 17, 1996
    Assignee: Glaxo Wellcome Inc.
    Inventors: Salvador E. Moncada, Richard M. J. Palmer
  • Prostacyclin treatment of thrombosis
    Patent number: 4404212
    Abstract: Pharmaceutical combinations comprising (a) prostacyclin, dihydroprostacyclin or a pharmaceutically acceptable salt of either of these, and (b) a phosphodiesterase inhibitor. Pharmaceutical formulations comprising a combination as above and a pharmaceutically acceptable carrier. Methods are disclosed for preparing the combinations and the formulations.The combinations and formulations are useful for preventing or minimizing platelet aggregation in blood, blood products or blood substitutes for example in the treatment of thrombosis, gastric lesions and wounds, and in the extra-corporeal circulation of blood and in blood separation processes.
    Type: Grant
    Filed: July 2, 1981
    Date of Patent: September 13, 1983
    Assignee: Burroughs Wellcome Co.
    Inventor: Salvador E. Moncada
  • Treatment for gastric lesions
    Patent number: 4393063
    Abstract: Pharmaceutical combinations comprising (a) prostacyclin, dihydroprostacyclin or a pharmaceutically acceptable salt of either of these, and (b) a phosphodiesterase inhibitor. Pharmaceutical formulations comprising a combination as above and a pharmaceutically acceptable carrier. Methods are disclosed for preparing the combinations and the formulations.The combinations and formulations are useful for preventing or minimising platelet aggregation in blood, blood products or blood substitutes for example in the treatment of thrombosis, gastric lesions and wounds, and in the extra-corporeal circulation of blood and in blood separation processes.
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: July 12, 1983
    Assignee: Burroughs Wellcome Co.
    Inventor: Salvador E. Moncada
  • Pharmaceutical compositions
    Patent number: 4337254
    Abstract: Pharmaceutical combinations comprising (a) prostacyclin, dihydroprostacyclin or a pharmaceutically acceptable salt of either of these, and (b) a phosphodiesterase inhibitor. Pharmaceutical formulations comprising a combination as above and a pharmaceutically acceptable carrier. Methods are disclosed for preparing the combinations and the formulations.The combinations and formulations are useful for preventing or minimizing platelet aggregation in blood, blood products or blood substitutes for example in the treatment of thrombosis, gastric lesions and wounds, and in the extra-corporeal circulation of blood and in blood separation processes.
    Type: Grant
    Filed: May 18, 1978
    Date of Patent: June 29, 1982
    Assignee: Burroughs Wellcome Co.
    Inventor: Salvador E. Moncada