Patents by Inventor Salvatore GUGLIELMINO

Salvatore GUGLIELMINO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conformational mimotopes for detecting specific antibodies
    Patent number: 11982679
    Abstract: The present invention relates to a method for obtaining protein mimotopes occurring in at least two distinct 3D conformations. In a further embodiment, a method for detecting antibodies with diagnostic relevance using said mimotopes is claimed. In a preferred embodiment, said methods are applied to Alzheimer's disease.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: May 14, 2024
    Assignee: DISTRETTO TECNOLOGICO SICLILIA MICRO E NANO SISTEMI S.C.A.R.L.
    Inventors: Salvatore Guglielmino, Laura Maria De Plano, Santina Carnazza, Domenico Franco, Alessandra Nicoletti, Mario Zappia, Sabrina Conoci, Salvatore Petralia
  • METHOD FOR DETERMINING THE PRESENCE OF A TARGET MICROORGANISM IN A BIOLOGICAL SAMPLE
    Publication number: 20240142449
    Abstract: The present invention relates to a method for determining the presence of a target microorganism in a biological sample comprising the steps of: providing a strip made of porous material, said strip having at least one fixation zone on which at least one phage exposing a peptide selective for said microorganism is fixed, and a deposition zone, separated from said fixation zone and intended to receive a portion of said biological sample, said phage being bound to a marker in deactivated form; contacting said biological sample with said strip on said deposition zone and eluting said microorganism through said strip so that said microorganism reaches said fixation zone to form a phage-target microorganism complex and release said marker in activated form; detecting said marker in activated form.
    Type: Application
    Filed: March 8, 2022
    Publication date: May 2, 2024
    Inventors: Sabrina Conoci, Francesco Traina, Salvatore Guglielmino
  • CONFORMATIONAL MIMOTOPES FOR DETECTING SPECIFIC ANTIBODIES
    Publication number: 20190383834
    Abstract: The present invention relates to a method for obtaining protein mimotopes occurring in at least two distinct 3D conformations. In a further embodiment, a method for detecting antibodies with diagnostic relevance using said mimotopes is claimed. In a preferred embodiment, said methods are applied to Alzheimer's disease.
    Type: Application
    Filed: November 27, 2017
    Publication date: December 19, 2019
    Inventors: Salvatore GUGLIELMINO, Laura Maria DE PLANO, Santina CARNAZZA, Domenico FRANCO, Alessandra NICOLETTI, Mario ZAPPIA, Sabrina CONOCI, Salvo PETRALIA