Patents by Inventor Salvatore Incandela

Salvatore Incandela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of iodinated contrast agent
    Patent number: 8624061
    Abstract: The present invention relies on a process for the preparation of non ionic iodinated contrast agents and, in more details, it relates to a process for the preparation of Iopamidol in high yields and with a high degree of purity. In more details, the invention discloses a process for the preparation of a compound of formula (III) comprising the condensation reaction a compound of formula (II) with 2-amino-1,3-propandiol, being said reaction carried out in an aprotic dipolar solvent and in the presence of an alkaline or alkaline rare earth metal oxide or hydroxide.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: January 7, 2014
    Assignee: Bracco Imaging S.p.A.
    Inventors: Silvia Ceragioli, Giovanni Ciarciello, Salvatore Incandela, Pietro Minotti
  • Process For The Preparation Of Iodinated Contrast Agent
    Publication number: 20110207960
    Abstract: The present invention relies on a process for the preparation of non ionic iodinated contrast agents and, in more details, it relates to a process for the preparation of Iopamidol in high yields and with a high degree of purity. In more details, the invention discloses a process for the preparation of a compound of formula (III) comprising the 5 condensation reaction a compound of formula (II) with 2-amino-1,3-propandiol, being said reaction carried out in an aprotic dipolar solvent and in the presence of an alkaline or alkaline rare earth metal oxide or hydroxide.
    Type: Application
    Filed: November 2, 2009
    Publication date: August 25, 2011
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Silvia Ceragioli, Giovanni Ciarciello, Salvatore Incandela, Pietro Minotti
  • Process for the recovery of copper from aqueous solutions containing iodinated organic compounds
    Patent number: 6827856
    Abstract: The present invention relates to a process for recovering copper from solutions from the recovery of iodine from industrial wastes from the production of ionic and non-ionic iodinated X-ray contrast agents by use of chelating resins suitable for removing copper from aqueous solutions. The absorbed copper is displaced by treating the resins with a 10% hydrochloric or sulfuric acid solution.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: December 7, 2004
    Assignee: Bracco Imaging S.p.A.
    Inventors: Nicola Desantis, Salvatore Incandela
  • Process for the recovery of iodine from aqueous solutions containing iodinated organic compounds
    Patent number: 6602419
    Abstract: A process for the recovery of iodine from mother liquors or wastes containing iodinated organic compounds, by mineralisation of organic iodine and subsequent transformation of the formed iodide into elementary iodine, characterized in that the aqueous solution is concentrated to a suitable volume before the mineralisation step, under atmospheric pressure and at the boiling temperature, and said solution is purified by nanofiltration.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 5, 2003
    Assignee: Bracco Imagining S.p.A.
    Inventors: Nicola Desantis, Ilaria Peretto, Salvatore Incandela, Carlo Felice Viscardi
  • Process for the recovery of copper from aqueous solutions containing iodinated organic compounds
    Publication number: 20030057161
    Abstract: The present invention relates to a process for recovering copper from solutions from the recovery of iodine from industrial wastes from the production of ionic and non-ionic iodinated X-ray contrast agents by use of chelating resins suitable for removing copper from aqueous solutions. The absorbed copper is displaced by treating the resins with a 10% hydrochloric or sulfuric acid solution.
    Type: Application
    Filed: July 9, 2002
    Publication date: March 27, 2003
    Inventors: Nicola Desantis, Salvatore Incandela
  • Process for the preparation of S-N,N?-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
    Patent number: 6262303
    Abstract: A process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide, comprising the formation of S-N,N′-bis[2-hydro-xy-1-(hydroxymethyl)ethyl]-5-[(2-(acetyloxy)-1-oxopro-pyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide star-ting from S-(−)-5-[[2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride and 2-amino-1,3-propanediol in a solvent, characterized in that the solvent is selected from the group consisting of: lower alcohols, monoalkyl ether glycols and straight or branched cyclic alkyl ethers.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: July 17, 2001
    Assignee: Dibra S.p.A.
    Inventors: Nicola De Santis, Salvatore Incandela