Patents by Inventor Salvatore Vomero

Salvatore Vomero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazo[1,2-?]pyrazin-3(7)-one derivatives bearing a new electron-rich structure
    Patent number: 8546147
    Abstract: The present invention relates to compound of formula I: and their use as chemiluminescent and/or bioluminescent reagents.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: October 1, 2013
    Assignee: Universita degli Studi di Siena
    Inventors: Germano Giuliani, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero
  • Amidine, thiourea and guanidine derivatives of 2-aminobenzothiazoles and aminobenzothiazines for their use as pharmacological agents for the treatment of neurodegenerative pathologies
    Patent number: 8420634
    Abstract: Amidine, thiourea and guanidine derivatives of appropriately substituted 2-aminobenzothiazoles, 2-amino-3,1-4H-benzothiazines and 3-amino-1,4-3H-benzothiazines, as understood from formula (I), the related pharmaceutically acceptable salts and solvates thereof: and the use of the products and the corresponding pharmaceutical formulations for the treatment of neurodegenerative pathologies such as cerebral ischemia, neurodegeneration induced by cranial trauma, Alzheimer's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: April 16, 2013
    Assignee: Rottapharm S.p.A.
    Inventors: Maurizio Anzini, Antonio Giordani, Francesco Makovec, Andrea Cappelli, Salvatore Vomero, Gianfranco Caselli, Lucio Claudio Rovati
  • IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE
    Publication number: 20120171703
    Abstract: The present invention relates to compound of formula I: and their use as chemiluminescent and/or bioluminescent reagents.
    Type: Application
    Filed: July 12, 2010
    Publication date: July 5, 2012
    Applicant: UNIVERSITÁ DEGLI STUDI DI SIENA
    Inventors: Germano Giuliani, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero
  • AMIDINE, THIOUREA AND GUANIDINE DERIVATIVES OF 2-AMINOBENZOTHIAZOLES AND AMINOBENZOTHIAZINES FOR THEIR USE AS PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE PATHOLOGIES
    Publication number: 20100197670
    Abstract: Amidine, thiourea and guanidine derivatives of appropriately substituted 2-aminobenzothiazoles, 2-amino-3,1-4H-benzothiazines and 3-amino-1,4-3H-benzothiazines, as understood from formula (I), the related pharmaceutically acceptable salts and solvates thereof: and the use of the products and the corresponding pharmaceutical formulations for the treatment of neurodegenerative pathologies such as cerebral ischemia, neurodegeneration induced by cranial trauma, Alzheimer's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
    Type: Application
    Filed: September 22, 2008
    Publication date: August 5, 2010
    Inventors: Maurizio Anzini, Antonio Giordani, Francesco Makovec, Andrea Cappelli, Salvatore Vomero, Gianfranco Caselli, Lucio Claudio Rovati
  • Basic derivatives of benz[e] isoindol-1-ones and pyrrolo[3,4-c] quinolin-1-ones with 5-HT3-antagonistic activity, their preparation and their therapeutic use
    Patent number: 6413978
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: in which X is CH or N, R is H, Cl or OR1 in which R1 is H or an alkyl group having from 1 to 3 carbon atoms, Het is the 3-endotropyl group (that is, the 8-methyl-8-azadicyclo[3.2.l]oct-3-yl group) or the 3-quinuclidyl group (that is, the 1-azadicyclo[2.2.2]oct-3-yl group); these compounds have been found to be potent and selective antagonists of the 5-HT3 serotonin-like receptor and can therefore be used, for example, as anti-emetics as well as in various pathological conditions of the central nervous system, and as antitussives.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: July 2, 2002
    Assignee: Rotta Research Laboratorium S.p.A.
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati
  • Novel basic derivatives of benz[e] isoindol-1-ones and pyrrolo[3,4-c] quinolin-1ones with 5-HT3-antagonistic activity, their preparation and their therapeutic use
    Publication number: 20020042426
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: 1
    Type: Application
    Filed: October 2, 2001
    Publication date: April 11, 2002
    Applicant: ROTTA RESEARCH LABORATORIUM S.p.A.
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati
  • Basic derivatives of benz[E]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones with 5-HT3-antagonistic activity, their preparation and their therapeutic use
    Patent number: 6323216
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: in which X is CH or N, R is H, Cl or OR1 in which R1 is H or an alkyl group having from 1 to 3 carbon atoms, Het is the 3-endotropyl group (that is, the 8-methyl-8-azadicyclo[3.2.1]oct-3-yl group) or the 3-quinuclidyl group (that is, the 1-azadicyclo[2.2.2]oct-3-yl group); these compounds have been found to be potent and selective antagonists of the 5-HT3 serotonin-like receptor and can therefore be used, for example, as anti-emetics as well as in various pathological conditions of the central nervous system, and as antitussives.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: November 27, 2001
    Assignee: Rotta Research Laboratorium S.p.A
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati