Abstract: An immunomodulatory combination including: (i) a lipid conjugate comprising an immunomodulatory agent covalently linked to a lipophilic moiety by a cleavable linkage or through a cleavable linker, and (ii) an antigen and/or one or more nucleic acids that encode the antigen. The antigen is a protein, polypeptide, peptide, lipoprotein, glycolipid, polynucleotide, or polysaccharide. The lipid conjugate and the antigen and/or the one or more nucleic acids that encode the antigen are formulated in separate delivery vehicles or co-formulated in the same delivery vehicle.

Abstract: Methods and system include power harvesting with process and device monitoring. A power management system including a solar cell can be integrated with a display panel into a common housing. A capacitor and a rechargeable battery connected to the power management system can receive power from the solar cell and provide electrical power, first from the capacitor and then second from the rechargeable battery, to electronic components including the display engaged in monitoring processes and devices deployed in isolated locations. Electronics can include a microprocessor programmed to provide collected data display on the display panel and wireless transmission to a remote monitoring station. A rotatable stem operated by a step-motor and connected to the common housing can orient the integrated display and solar cell towards sunlight according to an internal time clock synchronizing movement of the display panel via a step motor and thereby maximize harvesting of electrical energy.

Abstract: Methods and system include power harvesting with process and device monitoring. A power management system including a solar cell can be integrated with a display panel into a common housing. A capacitor and a rechargeable battery connected to the power management system can receive power from the solar cell and provide electrical power, first from the capacitor and then second from the rechargeable battery, to electronic components including the display engaged in monitoring processes and devices deployed in isolated locations. Electronics can include a microprocessor programmed to provide collected data display on the display panel and wireless transmission to a remote monitoring station. A rotatable stem operated by a step-motor and connected to the common housing can orient the integrated display and solar cell towards sunlight according to an internal time clock synchronizing movement of the display panel via a step motor and thereby maximize harvesting of electrical energy.

Abstract: Disclosed herein is a lipid having a net charge at physiological pH, and being covalently attached to a lipid moiety. The lipid moiety comprises a hydrocarbon structure having two or more linked hydrocarbon chains, optionally having cis or trans C?C, at least one of said chains being covalently attached to the head group optionally via the linker region. The hydrocarbon chains are bonded to one another at a branch point at an internal carbon of the chain attached to the linker region, which branch point comprises a functional group having an electronegative atom. The hydrocarbon chains each have between 1 and 40 carbon atoms, wherein the hydrocarbon structure in total comprises between 10 and 150 carbon atoms. Advantageously, the hydrocarbon structure may assume a generally flared shape for enhanced delivery of cargo molecules. Further provided are delivery vehicles comprising the lipids.

Abstract: The application relates to a lipid conjugate of formula M-X1-L wherein M is a molecule of interest such as a drug moiety; X1 is a linker group such as ester, ether or carbamate; and L is a lipid scaffold represented by formula (IId): -L1-[L2(H)(X2R)]n-L3-[L4(H)(X2R)]p-L5-L6 and wherein L comprises 5 to 40 carbon atoms and 0 to 2 carbon-carbon double bonds. The lipid conjugate can p be formulated in a drug delivery vehicle such as a lipid nanoparticle (LNP).

Abstract: An interconnection assembly includes a chassis, and cam plates that are rotatably coupled to the chassis to pivot about a plurality of rotational axises. An upper cam plate is operatively coupled to a deadbolt. The upper cam plate has a cam surface. A lower cam plate is rotatably coupled to the chassis to pivot about a second rotational axis. The lower cam plate is operatively coupled to an interior latch bolt handle. The lower cam plate has a cam slot. A linkage bar is rotatably coupled to the chassis to pivot about a pivot axis. The linkage bar has a first linkage portion having a first cam follower configured to operatively engage the cam surface of the upper cam plate and has a second linkage portion having a second cam follower operatively received in the cam slot of the lower cam plate.

Abstract: A door handle set includes a handle assembly having a primary lock and having a handle rotatable about a primary rotational axis. A latch bolt assembly has a latch bolt. The latch bolt assembly is operatively coupled to the handle assembly, wherein a rotation of the handle results in a linear translation of the latch bolt. A supplemental lock has a second axis parallel to, and spaced apart from, the primary rotational axis. The supplemental lock has an actuator that is operable relative to the second axis. The supplemental lock is configured to selectively block the rotation of the handle regardless of the locking state of the primary lock.

Abstract: An electrical communications system includes a communications cable that couples electrical communications between a first device, a second device, and a third device, the communications cable having a group of root wires that electronically and modularly connects to the third device to permit electronic communication with the third device and allow communications and signaling between the first, second, and third devices without the functionalities of each the first, second, and third devices detrimentally affecting one another.

Abstract: A mobile rack includes a releasable casing including a front wall having opening elements; a frame member secured to the front wall and including an opening member aligned with the opening elements, a recess at a second side, and a well between the recess and the opening member; a spring-actuated door having a first side hingedly secured to a first side of the frame member and including an opening aligned with the opening member, and a latch at a second side; a spring-actuated lock activation mechanism including a key hole, a hollow shank aligned with the key hole, and a hollow lock element put on a rear portion of the hollow shank and having a projection on a first side; and a spring-actuated auxiliary lock mechanism pivotably secured to the second side of the frame member and including a hook in the well, and an extension.

Abstract: A process for hydrocarbon recovery from a hydrocarbon-bearing formation utilizing an injection well for the injection of a mobilizing and displacing fluid, such as steam, into the formation and a production well, spaced from the injection well, and through which hydrocarbon is recovered. The process includes injecting a surfactant and a gas into the production well for a first period of time to thereby emplace or form foam to an extent sufficient to modify the path of flow in an inter-well region between the injection well and the production well and in an area spaced from the inter-well region of the reservoir, which area is in fluid communication with at least one of the injection well and the production well. The process also includes injecting fluid into the injection well to cause the flow of hydrocarbon in the formation and recovering the hydrocarbon through the production well.

Abstract: Removable blades of fan include a rear base, a front cover corresponding to the rear base, and a plurality of frames covered with a plurality of sponge blades. Each of a plurality of sponge blades is inserted through a frame while a lug is positioned on one end of the frame. A flapper is arranged between the lug and the frame. Each of the frame is mounted between the rear base and the front cover by the lug. The front cover and the rear base, together with the sponge blades extending outward so as to form a casing for the main body of the fan.

Abstract: A bat (10) comprises a near portion (20) and a far portion (80) joined by a weld (90). Near portion (20) generally comprises a fiber/resin composite portion (30) including a proximal end (32), a distal end (40), and a grip portion (36) therebetween, and a metal joining ring (50) including a proximal portion (54) including interlocking joining means (55), such as through bores (56) or contours (57), mechanically joining proximal portion (54) of ring (50) to distal end (40) of composite portion (30), and a distal portion (58). Far portion (80) includes a proximal portion (82) joined, such as by weld (90), to ring (50), a distal portion (87), and a barrel portion (86) therebetween.