Abstract: The present invention relates to methods for identifying, assessing, preventing, and treating cancer (e.g., head, neck, and/or lung cancers in humans). A variety of PD-L1 isoform biomarkers are provided, wherein alterations in the copy number of one or more of the biomarkers and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers is associated with cancer status and indicates amenability to treatment or prevention by modulating PD-1 and/or PD-L1 levels.

Abstract: An augmented lens assembly for use with a light source featuring a main lens component having one or a plurality of light refocusing elements associated with the main lens and arranged along at least one surface of the main lens of the lens assembly that provides for improved uniformity in light distribution and improved illumination. Luminaires featuring one or a plurality of augmented lens assemblies, associated light sources and optionally, baffles, further featuring one or more main lens components having one or more light refocusing elements associated with the main lens portion and arranged along at least one surface of the main lens to provide for improved uniformity in light distribution, improved illumination and aesthetic improvements to the visual appearance of the luminaires when observed in either a lighted or non-lighted condition.

Abstract: The present invention relates to methods for identifying, assessing, preventing, and treating cancer (e.g., head, neck, and/or lung cancers in humans). A variety of PD-L1 isoform biomarkers are provided, wherein alterations in the copy number of one or more of the biomarkers and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers is associated with cancer status and indicates amenability to treatment or prevention by modulating PD-1 and/or PD-L1 levels.

Abstract: A hand-help Remote Control and an associated Cradle or Host Adapter communicate to send and receive data. The Remote is battery powered, has an LCD screen and buttons and is intended for thumb operation in either hand. The Cradle unit is attached to a portable Music Player (or video player) such as the Apple iPod® and communicates with the Remote. The Host Adapter connects to a computer running a Music Player Software Application and communicates with the Remote. The Cradle or Host Adapter communicate wirelessly with the Remote and enable the user to control a Music Player, display and navigate through the Music Player database, select a particular item to play on the player and/or change sound properties such as volume output of the Cradle unit. The LCD also displays the status of the player such as song or video currently playing, position into the selection, volume level and other items.