Patents by Inventor Sam Gillette

Sam Gillette has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PDE4B inhibitors and uses therefor
    Patent number: 8470821
    Abstract: Compounds active on phosphodiesterase PDE4B are provided. Also provided herewith are compositions useful for treatment of PDE4B-mediated diseases or conditions, and methods for the use thereof.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: June 25, 2013
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Hanna Cho, Bruce England, Sam Gillette, Dean R. Artis, Rebecca Zuckerman, Chao Zhang
  • PDE4B INHIBITORS AND USES THEREFOR
    Publication number: 20090286793
    Abstract: Compounds active on phosphodiesterase PDE4B are provided. Also provided herewith are compositions useful for treatment of PDE4B-mediated diseases or conditions, and methods for the use thereof.
    Type: Application
    Filed: July 20, 2009
    Publication date: November 19, 2009
    Inventors: Prabha N. Ibrahim, Hanna Cho, Bruce England, Sam Gillette, Dean R. Artis, Rebecca Zuckerman, Chao Zhang
  • PDE4B inhibitors
    Patent number: 7605168
    Abstract: Compounds are described that are active on PDE4. Also described are crystal structures of PDE4B determined using X-ray crystallography, the use of PDE4B crystals and structural information for identifying molecular scaffolds, for developing ligands that bind to and modulate PDE4B, and for identifying improved ligands based on known ligands.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: October 20, 2009
    Assignee: Plexxikon, Inc.
    Inventors: Prabha N. Ibrahim, Ryan Bremer, Sam Gillette, Hanna Cho, Marika Nespi, Shumeye Mamo, Chao Zhang, Dean R. Artis, Byunghun Lee, Rebecca Zuckerman
  • PDE4B inhibitors and uses therefor
    Patent number: 7585859
    Abstract: Compounds active on phosphodiesterase PDE4B are provided. Also provided herewith are compositions useful for treatment of PDE4B-mediated diseases or conditions, and methods for the use thereof.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: September 8, 2009
    Assignee: Plexxikon, Inc.
    Inventors: Prabha N. Ibrahim, Hanna Cho, Bruce England, Sam Gillette, Dean R. Artis, Rebecca Zuckerman, Chao Zhang
  • PDE4B inhibitors
    Publication number: 20060100218
    Abstract: Compounds are described that are active on PDE4. Also described are crystal structures of PDE4B determined using X-ray crystallography, the use of PDE4B crystals and strucural information for identifying molecular scaffolds, for developing ligands that bind to and modulate PDE4B, and for identifying improved ligands based on known ligands.
    Type: Application
    Filed: September 2, 2005
    Publication date: May 11, 2006
    Inventors: Prabha Ibrahim, Ryan Bremer, Sam Gillette, Hanna Cho, Marika Nespi, Shumeye Mamo, Chao Zhang, Dean Artis, Byunghun Lee, Rebecca Zuckerman
  • PDE4B inhibitors and uses therefor
    Publication number: 20060041006
    Abstract: Compounds active on phosphodiesterase PDE4B are provided. Also provided herewith are compositions useful for treatment of PDE4B-mediated diseases or conditions, and methods for the use thereof.
    Type: Application
    Filed: May 6, 2005
    Publication date: February 23, 2006
    Inventors: Prabha Ibrahim, Hanna Cho, Bruce England, Sam Gillette, Dean Artis, Rebecca Zuckerman, Chao Zhang