Patents by Inventor Sam Rose

Sam Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5965086
    Abstract: Sterile interconnection between disassociated segments of thermostable, compressible fluid conduit tubing is achieved by arranging within the bore of the free end of each segment a conductive hollow metal tube so as to establish a connected fluid flow path from one segment to the other, through the metal tube, and then sterilizing the connection by induction heating.
    Type: Grant
    Filed: January 27, 1993
    Date of Patent: October 12, 1999
    Assignee: Baxter Healthcare Corporation
    Inventors: Sam Rose, Glenn C. Buchanan
  • Patent number: 5223428
    Abstract: Cells producing a desired product or products, such as antibodies, are cultured with a culture medium comprising lymph. The lymph is continuously flowed across a semi-permeable membrane, on the other side of which are the cells to be cultured. The membrane is sized so as to retain cells, and their desired products, on one side of the membrane while permitting components of the lymph-containing culture medium (flowing across the other side of the membrane) to pass through the membrane to provide nutrition, etc. to the culturing cells.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: June 29, 1993
    Assignee: Baxter International Inc.
    Inventor: Sam Rose
  • Patent number: 4659655
    Abstract: The invention relates to techniques for isolating from a mixed population of cells disired living cells either producing and releasing a particular product or having a characteristic molecule on their surface. The isolation techniques depend upon the localized interaction between the product (or molecule) and other agents added to the system such that distinguishable conditions can be caused to occur (or not occur) only in the immediate vicinity of desired cells which produced and released the product or which contain the molecule on their surface.
    Type: Grant
    Filed: November 23, 1982
    Date of Patent: April 21, 1987
    Assignee: Bio-Response, Inc.
    Inventor: Sam Rose
  • Patent number: 4508819
    Abstract: Disclosed herein is a process for the in vitro culturing of cells or tissues such that the cells or tissues grow, behave and function in substantially the manner such cells or tissues grow, behave and function within the body, wherein the cells or tissues are contacted or bathed with fresh flowing cell-free lymph. The cell-free lymph may be obtained directly from a living host by removing lymph from the host, rendering the lymph cell-free by suitable means and then using the cell-free lymph as the culture medium for cells or tissues of either the same or different species as that of the host. The cells or tissues preferably are contacted with the cell-free lymph in a chamber in which the cells or tissues are exposed either directly to the flowing lymph or to components thereof.
    Type: Grant
    Filed: May 21, 1982
    Date of Patent: April 2, 1985
    Assignee: Bio-Response, Inc.
    Inventor: Sam Rose
  • Patent number: 4189470
    Abstract: A process for the removal of a specific antibody from the lymph fluid free of lymph cells is disclosed. The lymph is taken from a subject (e.g., human or animal) by means of a thoracic duct fistula by raising the pressure of the central venous system in order that the pressure is above the atmospheric pressure of the thoracic duct. Lymph is separated into cells and lymph fluid containing antibodies. Cells are returned to the subject intravenously. Lymph fluid is mixed with substrate particles attached with specific antigens. An antibody-antigen-substrate particle complex is formed and removed. Subsequently, specific antibody can be split from the specific antigens attached to a substrate particle. The antigen-attached substrate particles can then be re-used. Specific antibody can be introduced into another subject or used for other purposes in biology, in chemistry, and in veterinary and clinical medicine.
    Type: Grant
    Filed: November 15, 1977
    Date of Patent: February 19, 1980
    Assignee: Bio-Response, Inc.
    Inventor: Sam Rose
  • Patent number: 4146754
    Abstract: The disclosed signalling apparatus provides a different identifying signal in response to a ringing signal for one or more telephone station sets connected by a common line to a centralized switching, control and signalling machine. The different identifying signals are generated in response to the number and timing of ringing signals applied to the line. If a first ring is sensed and within a predetermined first time a second ring is sensed, a first identifying signal is initiated. If a first ring is sensed and after the predetermined first time but before a predetermined second time a second ring is sensed, a second identifying signal is initiated. If a first ring is sensed, but a second ring is not sensed before the predetermined second time, the signalling apparatus is reset to initial conditions.
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: March 27, 1979
    Inventor: Sam Rose
  • Patent number: 4064006
    Abstract: A process for augmenting production of a specific antibody from a patient including the steps of administering a specific antigen to the patient to cause production of the specific antibody, or choosing a subject containing an antigen, e.g.
    Type: Grant
    Filed: February 11, 1975
    Date of Patent: December 20, 1977
    Assignee: Bio-Response, Inc.
    Inventor: Sam Rose
  • Patent number: 3964467
    Abstract: A process for augmenting production of a specific antibody from a patient including the steps of administering a specific antigen to the patient to cause production of the specific antibody, or choosing a subject containing an antigen, e.g.
    Type: Grant
    Filed: April 9, 1973
    Date of Patent: June 22, 1976
    Assignee: BIO Response Inc.
    Inventor: Sam Rose