Patents by Inventor Samedy Ouk

Samedy Ouk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and materials for assessing prostate cancer therapies and compounds
    Publication number: 20070191443
    Abstract: A modest (2-5 fold) increase in androgen receptor (AR) mRNA is the only expression change consistently associated with developing resistance to antiandrogen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low levels of residual ligand and altering the normal response to antagonists. This invention provides cell based assays for use in the examination of new therapeutic modalities and provides for the design of novel antiandrogen compounds.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 16, 2007
    Inventors: Michael Jung, Samedy Ouk, Charles Sawyers, Charlie Chen, Derek Welsbie
  • Diarylhydantoin compounds
    Publication number: 20070004753
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: May 15, 2006
    Publication date: January 4, 2007
    Applicant: The Regents of the University of California
    Inventors: Charles Sawyers, Michael Jung, Charlie Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • Monomethylation of nitrogeneous heterocycles
    Patent number: 7022845
    Abstract: A process for the monomethylation of nitrogenous heterocycles having at least one nitrogen atom bonded to a hydrogen atom by reacting the nitrogenous heterocycle with dimethyl carbonate at a temperature of between 100° and 200° C. and a pressure of between 0.93×105 Pa and 1.07×105 Pa while methanol produced during the reaction is distilled off as it is formed.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: April 4, 2006
    Assignee: Group SNPE
    Inventors: Elisabeth Borredon, Berhard Chabaud, Antoine Gaset, Sophie Thiebaud-Roux, Samedy Ouk
  • Process for the synthesis of aryl alkyl monoethers
    Patent number: 6794547
    Abstract: The invention relates to a process for the synthesis of aryl alkyl monoethers by reaction of a phenol compound, comprising one or more hydroxyl groups attached to the aromatic system, and of a dialkyl carbonate. It is a solvent-free process carried out at a pressure of between 0.93×105 Pa and 1.07×105 Pa, at a temperature of between 100° C. and 200° C., and in the presence of a catalyst chosen from the group consisting of alkaline carbonates and alkaline hydroxides. The dialkyl carbonate is added gradually to the reaction mixture.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: September 21, 2004
    Assignee: SNPE
    Inventors: Elisabeth Borredon, Antoine Gaset, Samedy Ouk, Sophie Thiebaud-Roux, Pierre Le Gars
  • Monomethylation of nitrogeneous heterocycles
    Publication number: 20040024205
    Abstract: A process for the monomethylation of nitrogenous heterocycles having at least one nitrogen atom bonded to a hydrogen atom by reacting the nitrogenous heterocycle with dimethyl carbonate at a temperature of between 100° and 200° C. and a pressure of between 0.93×105 Pa and 1.07×105 Pa while methanol produced during the reaction is distilled off as it is formed.
    Type: Application
    Filed: July 31, 2003
    Publication date: February 5, 2004
    Inventors: Elisabeth Borredon, Berhard Chabaud, Antoine Gaset, Sophie Thiebaud-Roux, Samedy Ouk
  • Process for the synthesis of aryl alkyl monoethers
    Publication number: 20020193641
    Abstract: The invention relates to a process for the synthesis of aryl alkyl monoethers by reaction of a phenol compound, comprising one or more hydroxyl groups attached to the aromatic system, and of a dialkyl carbonate. It is a solvent-free process carried out at a pressure of between 0.93×105 Pa and 1.07×105 Pa, at a temperature of between 100° C. and 200° C., and in the presence of a catalyst chosen from the group consisting of alkaline carbonates and alkaline hydroxides. The dialkyl carbonate is added gradually to the reaction mixture.
    Type: Application
    Filed: February 20, 2002
    Publication date: December 19, 2002
    Inventors: Elisabeth Borredon, Antoine Gaset, Samedy Ouk, Sophie Thiebaud-Roux, Pierre Le Gars