Patents by Inventor Sameer Goregaoker

Sameer Goregaoker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR SHORT INTERFERING NUCLEIC ACID INHIBITION OF Nav 1.8
    Publication number: 20140256787
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Na.sub.v1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Application
    Filed: April 22, 2014
    Publication date: September 11, 2014
    Inventors: Sameer Goregaoker, John C. Hunter, Tony Priestley
  • Compositions and methods for short interfering nucleic acid inhibition of Na1.8
    Patent number: 8729045
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: May 20, 2014
    Assignee: Merck Sharp & Dohme Corp. and Canji, Inc.
    Inventors: Sameer Goregaoker, John C. Hunter, Tony Priestley
  • Compositions and methods for short interfering nucleic acid inhibition of Na1.8
    Patent number: 8309703
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: November 13, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Sameer Goregaoker, John C. Hunter, Tony Priestley
  • COMPOSITIONS AND METHODS FOR SHORT INTERFERING NUCLEIC ACID INHIBITION OF NAV1.8
    Publication number: 20100305192
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Application
    Filed: May 28, 2010
    Publication date: December 2, 2010
    Applicants: SCHERING CORPORATION, CANJI, INC.
    Inventors: SAMEER GOREGAOKER, JOHN C. HUNTER, TONY PRIESTLEY
  • Compositions and methods for short interfering nucleic acid inhibition of Na1.8
    Patent number: 7786291
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: August 31, 2010
    Assignee: Schering Corporation
    Inventors: Sameer Goregaoker, John C. Hunter, Tony Priestley
  • Compositions and methods for short interfering nucleic acid inhibition of NAv1.8
    Publication number: 20060199779
    Abstract: The invention provides short interfering nucleic acids, either single-stranded or double-stranded, that cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; to pharmaceutical compositions comprising such short interfering nucleic acids; recombinant vectors comprising such short interfering nucleic acids; a method for inhibiting translation of an mRNA; a method for inhibiting expression of a polypeptide; a method for blocking the membrane potential in a cell; a method for blocking the sodium current in a cell; and a method for inhibiting chronic pain.
    Type: Application
    Filed: October 26, 2005
    Publication date: September 7, 2006
    Inventors: Sameer Goregaoker, John Hunter, Tony Priestley