Abstract: The present disclosure provides a novel combination of a NOD2 agonist with an immunotherapeutic agent for the treatment of cancer. The disclosure also comprises methods of treatments wherein a pharmaceutical composition of NOD2 agonist is used in combination with an immunotherapeutic agent. A pharmaceutical composition comprises of NOD2 agonist and an immunotherapeutic agent comprising PD-1 axis antagonist or CTLA4 antagonist with a pharmaceutically acceptable diluent or carrier.

Abstract: Particular examples described herein provide for an electronic device, such as a notebook computer or laptop, which includes a circuit board coupled to a plurality of electronic components (which includes any type of hardware, elements, circuitry, etc.). The electronic device may also include a connector assembly that is positioned within at least a portion of a recess of the electronic device, where the connector assembly includes: a first assembly that is to receive a connector; and a second assembly that is to receive an identification module that is to provide an association between a user and the electronic device.

Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the ax

Abstract: Embodiments of an apparatus and system are described for a hybrid computing device. Some embodiments may comprise a computing device having an enclosure arranged to support a display on a front of the enclosure and a cover mechanically coupled to a side of the enclosure, the cover comprising a first portion having at least one integrated input device and a second portion having at least one flexible seam arranged to allow the second portion to adjustably pivot around the seam. Other embodiments are described and claimed.

Abstract: Particular examples described herein provide for an electronic device, such as a notebook computer or laptop, which includes a circuit board coupled to a plurality of electronic components (which includes any type of hardware, elements, circuitry, etc.). The electronic device may also include a connector assembly that is positioned within at least a portion of a recess of the electronic device, where the connector assembly includes: a first assembly that is to receive a connector; and a second assembly that is to receive an identification module that is to provide an association between a user and the electronic device.

Abstract: Particular examples described herein provide for an electronic device, such as a notebook computer or laptop, which includes a circuit board coupled to a plurality of electronic components (which includes any type of hardware, elements, circuitry, etc.). The electronic device may also include a connector assembly that is positioned within at least a portion of a recess of the electronic device, where the connector assembly includes: a first assembly that is to receive a connector; and a second assembly that is to receive an identification module that is to provide an association between a user and the electronic device.

Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; a proximal balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the proximal balloon; a push tube slidably mounted to the sleeve; and a distal balloon secured to the distal end of the push tube, the interior of the distal balloon being in fluid communication with the push tube, wherein the distal balloon is capable of assuming a deflated condition and an inflated condition, and further wherein when the distal balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and when the distal balloon is in its inflated condition, the axial opening is closed down.

Abstract: Embodiments of an apparatus and system are described for a hybrid computing device. Some embodiments may comprise a computing device having an enclosure arranged to support a display on a front of the enclosure, a projector adjustment ring integrated into a portion of the perimeter of the enclosure, and a projector module adjustably coupled to the projector adjustment ring. In various embodiments, the projector module may be arranged for dual-axis rotation within the projector adjustment ring. Other embodiments are described and claimed.

Abstract: Apparatuses, methods and storage media associated with parking management are disclosed herein. In embodiments, a system may include a plurality of sensors disposed around an expanse of space to collect occupancy data of the expanse of space; and a parking management unit disposed in or adjourning the expanse of space to manage parking of vehicles in the expanse of space, based at least in part on the occupancy data collected by the plurality of sensors. The expanse of space may be a linear expanse of roadway space adjacent to a sidewalk, or an aerial expanse of surface space of a parking lot or a floor of a parking structure. Parking spaces within the expanse of space may be fixed or variably sized/typed. Other embodiments may be disclosed or claimed.

Abstract: In one example embodiment, a method of adaptive video streaming includes receiving, by a server, a request for a video segment from an end user device and determining, by the server, a plurality of variables, the plurality of variables including at least one of a download time of a previously requested video segment by the end user device, a fullness of a buffer at the end user device and a size of the buffer. The method further includes determining, by the server, a rate of the requested video segment based on one or more of the determined plurality of variables and sending, by the server, the requested video segment at the determined rate to the end user device.

Abstract: The invention discloses a method of treating, preventing or ameliorating tumor or symptoms resulting from defective neurofibromatosis type-2 gene in a subject by administering to the subject a therapeutically effective amount of a ubiquitin-proteasome system inhibitor which inhibits or slows the growth of neurofibromatosis type-2-deficient tumor or associated symptoms. The invention also includes methods of diagnosis and screening of patients for neurofibromatosis type-2 and mesothelioma.

Abstract: Embodiments of an apparatus and system are described for a hybrid computing device. Some embodiments may comprise a computing device having an enclosure arranged to support a display on a front of the enclosure, a projector adjustment ring integrated into a portion of the perimeter of the enclosure, and a projector module adjustably coupled to the projector adjustment ring. In various embodiments, the projector module may be arranged for dual-axis rotation within the projector adjustment ring. Other embodiments are described and claimed.

Abstract: A metric of cell congestion is determined using an average physical resource block rate that is expected to be allocated for a very active user equipment bearer that is a persistent average rate. The average physical resource block rate is mapped to congestion levels and this information is exported to an application function or a radio access network function in order to mitigate congestion. An average bearer throughput for the user equipment can be calculated based on the average physical resource block rate.

Abstract: An application type of a bearer is classified by computing statistics vectors of bearer metrics and locating points on a label map corresponding to the statistics vectors to obtain application type information. The application type information is exported to a network node to control an operation of application. The bearer metrics include bearer identifier information and bearer condition information, where the bearer condition information includes channel condition information and cell congestion level information. The bearers are paired, such that uplink and downlink bearers for a same application are identified, so that paired bearers are classified together. The label map is produced using previously classified bearer information to calculate cluster centroids and cluster regions that define portions of the map for particular application types.

Abstract: There is provided a composition suitable for oral transmucosal administration (sublingual) comprising dexmedetomidine. The composition is useful for the treatment of sleep disorders such as insomnia and capable of providing sleep on demand. The composition comprises an effective amount of dexmedetomidine or pharmaceutically acceptable salts thereof, solvates thereof, or derivatives thereof, formulated for delivery of dexmedetomidine across a subject's oral mucosa.