Patents by Inventor Samia ACI-SÈCHE

Samia ACI-SÈCHE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3,6-DIHYDROPYRIDINE-1-(2H)-CARBOXAMIDE DERIVATIVES AS LIMK AND/OR ROCK KINASES INHIBITORS FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20230312576
    Abstract: The present invention concerns a compound of formula (1), in particular as LIMK and/or ROCK kinases inhibitors. The present invention also concerns these new inhibitors for use for the treatment of a condition selected in the group consisting of: cancers, virion infections, ocular hypertension and glaucoma formation, Neurofibromatosis type 1 and 2, psoriatic lesions, inflammatory diseases and hyperalgesia, central sensitization and chronic pain, reproduction erectile dysfunction, and neuronal diseases.
    Type: Application
    Filed: May 25, 2021
    Publication date: October 5, 2023
    Inventors: Sylvain ROUTIER, Hélène BENEDETTI, Béatrice LÉE-MÉHEUST, Pascal BONNET, Karen PLÉ, Samia ACI-SÈCHE, Sandrine RUCHAUD, Abdennour BRAKA, Anthony CHAMPIRÉ, Christian ANDRES, Patrick VOURC'H
  • Selective c-FLIP Inhibitors as Anticancer Agents
    Publication number: 20190282563
    Abstract: The present invention provides nine selective c-FLIP inhibitors that are useful in the treatment of cancer, alone or in combination with other chemotherapeutic agents, in particular with TRAIL-based chemotherapeutic agents. The present invention also relates to pharmaceutical compositions and kits comprising at least one of the nine selective c-FLIP inhibitors and their use in methods for the treatment of cancer, in particular to overcome chemoresistance or to improve sensitivity of tumors to TRAIL-based therapy.
    Type: Application
    Filed: November 17, 2017
    Publication date: September 19, 2019
    Applicants: Centre National de la Recherche Scientifique, Universite de Rennes 1, Universite d'Orleans
    Inventors: Katherine YAACOUB, Thierry GUILLAUDEUX, Richard DANIELLOU, Pierre LAFITE, Samia ACI-SECHE, Pascal BONNET