Patents by Inventor Samina Alam

Samina Alam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parvovirus methods and compositions for killing neoplastic cells
    Patent number: 8980247
    Abstract: According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: March 17, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Craig M. Meyers, Samina Alam
  • PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS
    Publication number: 20120213736
    Abstract: According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same.
    Type: Application
    Filed: December 13, 2011
    Publication date: August 23, 2012
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Craig M. Meyers, Samina Alam
  • Parvovirus methods and compositions for killing neoplastic cells
    Patent number: 8080240
    Abstract: According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: December 20, 2011
    Assignee: The Penn State Research Foundation
    Inventors: Craig M. Meyers, Samina Alam
  • PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS
    Publication number: 20090117081
    Abstract: According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same.
    Type: Application
    Filed: October 21, 2005
    Publication date: May 7, 2009
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Craig M. Meyers, Samina Alam