Abstract: Systems, methods, apparatus, and a computer-readable medium are described for generating and receiving information regarding the current state of the active virtual machine in the host and switching the standby virtual machine from standby to active in response to determining that the current active virtual machine may no longer be able to service network packets.

Abstract: Provided are systems, methods, and computer-readable medium for enabling sharing of a multi-channel packet processor by multiple processes executing on a network device. The network device can include a memory management unit, configured to include an address map. The address map can include a reserved portion. The virtual machine can allocate a guest portion in the address map, where the guest portion is allocated in a part of the address map that does not include the reserved portion. A first channel from the packet processor can be assigned to the guest portion, and the virtual machine can use the first channel to receive packets. The reserved portion can be assigned to a host process executing on the network device. A second channel from the packet processor can be assigned to the reserved portion. The host process can transmit packets to the network using the second channel.

Abstract: Systems, methods, apparatus and computer-readable medium are described for improving efficiency and robustness for sharing data across different users, agents, processes, drivers, and applications in a system. A shared buffer between multiple entities may be used for sharing data such that the data is only stored once and accessed by multiple entities without copying the data over and over again. An example system may be a network device. For a received packet at a network interface of a network device, the packet may be stored directly in memory. The application or process responsible for accessing and/or manipulating the packet can directly do so by simply using a buffer pointer provided by the buffer manager.

Abstract: A network device may include various cards and modules, such as management modules, line cards, and switch fabric modules. In various implementations, these components can be “hot-plugged” meaning that the components can be inserted into and removed from the network device while the network device is powered on. In various implementations, hardware in the network device can identify when a component has been added. The hardware can notify a virtual machine, which can then notify the host operating system. The host operating system can added the component, and then notify the virtual machine to also add the component. Once the virtual machine has added the component, the component becomes available for use by processes executing on the virtual machine.

Abstract: Provided are systems, methods, and computer-readable medium for enabling sharing of a multi-channel packet processor by multiple processes executing on a network device. The network device can include a memory management unit, configured to include an address map. The address map can include a reserved portion. The virtual machine can allocate a guest portion in the address map, where the guest portion is allocated in a part of the address map that does not include the reserved portion. A first channel from the packet processor can be assigned to the guest portion, and the virtual machine can use the first channel to receive packets. The reserved portion can be assigned to a host process executing on the network device. A second channel from the packet processor can be assigned to the reserved portion. The host process can transmit packets to the network using the second channel.

Abstract: Provided are systems, methods, and computer-readable medium for enabling sharing of a multi-channel packet processor by multiple processes executing on a network device. The network device can include a memory management unit, configured to include an address map. The address map can include a reserved portion. The virtual machine can allocate a guest portion in the address map, where the guest portion is allocated in a part of the address map that does not include the reserved portion. A first channel from the packet processor can be assigned to the guest portion, and the virtual machine can use the first channel to receive packets. The reserved portion can be assigned to a host process executing on the network device. A second channel from the packet processor can be assigned to the reserved portion. The host process can transmit packets to the network using the second channel.

Abstract: A network device may include various cards and modules, such as management modules, line cards, and switch fabric modules. In various implementations, these components can be “hot-plugged” meaning that the components can be inserted into and removed from the network device while the network device is powered on. In various implementations, hardware in the network device can identify when a component has been added. The hardware can notify a virtual machine, which can then notify the host operating system. The host operating system can added the component, and then notify the virtual machine to also add the component. Once the virtual machine has added the component, the component becomes available for use by processes executing on the virtual machine.

Abstract: Systems, methods, apparatus and computer-readable medium are described for improving efficiency and robustness for sharing data across different users, agents, processes, drivers, and applications in a system. A shared buffer between multiple entities may be used for sharing data such that the data is only stored once and accessed by multiple entities without copying the data over and over again. An example system may be a network device. For a received packet at a network interface of a network device, the packet may be stored directly in memory. The application or process responsible for accessing and/or manipulating the packet can directly do so by simply using a buffer pointer provided by the buffer manager.

Abstract: Systems, methods, apparatus, and a computer-readable medium are described for generating and receiving information regarding the current state of the active virtual machine in the host and switching the standby virtual machine from standby to active in response to determining that the current active virtual machine may no longer be able to service network packets.

Abstract: Provided are systems, methods, and computer-readable medium for enabling sharing of a multi-channel packet processor by multiple processes executing on a network device. The network device can include a memory management unit, configured to include an address map. The address map can include a reserved portion. The virtual machine can allocate a guest portion in the address map, where the guest portion is allocated in a part of the address map that does not include the reserved portion. A first channel from the packet processor can be assigned to the guest portion, and the virtual machine can use the first channel to receive packets. The reserved portion can be assigned to a host process executing on the network device. A second channel from the packet processor can be assigned to the reserved portion. The host process can transmit packets to the network using the second channel.

Abstract: The present invention relates to a synergistic pharmaceutical composition comprising Compound C2 (Neo-isopulegol), C3 (Iso-pulegol) and C4 (Citronellol) derived from herbal seed extract of Litsea cubeba useful for the treatment of lung cancer. The present invention also relates to the activity of compounds C2 or C3 or C4 either alone or in combination in killing of A549 lung cancer cells.

Abstract: The present invention relates to a synergistic pharmaceutical composition comprising Compound C2 (Neo-isopulegol), C3 (Iso-pulegol) and C4 (Citronellol) derived from herbal seed extract of Litsea cubeba useful for the treatment of lung cancer. The present invention also relates to the activity of compounds C2 or C3 or C4 either alone or in combination in killing of A549 lung cancer cells.

Abstract: A pharmaceutically acceptable peroxovanadium(v) amine product, DmpzH[VO(02)2](Dmpz)], and its oral as well as injectable use for the treatment of Diabetes mellitus, wherein the said therapeutically stable compound is obtained by reacting V205 or vanadate with hydrogen peroxide and the amine, dimethylpyrazole (Dmpz), at pH 5.5 and temperature 0-4° C. DmpzH[VO(02)2](Dmpz)] is thus poised as a versatile insulin mimic adapted for targeting insulin signaling, stimulating adipogenesis, abrogating insulin stimulated down stream signals thereby lowering the incidence of insulin resistance and type-2 diabetes.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water:methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination.

Abstract: The present invention is directed to pharmaceutical compositions and methods for treatment of prostate cancer in a subject. The pharmaceutical composition includes a therapeutically effective amount of compound mahanine, or derivatives, or analogues, or pharmaceutically acceptable salt thereof. The present invention is further directed to a method of isolating compound mahanine from Murraya koenigii.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water:methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water:methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination.

Abstract: Described is an in vitro method for developing dendritic Langerhans type cells, for use in immunotherapy against cancer or infectious diseases and enhancement of graft survival in mammals. The method includes the steps of: culturing cells selected from peripheral blood monocytes and bone marrow cells in a medium containing platelets obtained from the same species or phylogenetically close species; and incubating the culture at 30 to 40° C. for a period sufficient to enable formation of mature dendritic Langerhans type cells.

Abstract: The present invention provides a method of treating acute and chronic myeloid leukemia (AML & CML) and lymphoid leukemia, said method comprising administering a pharmaceutical composition comprising pharmaceutically effective amount of chlorogenic acid (CA) and 3-o-p-Coumaryl quinic acid (PCQ) isolated from any plant parts of Piper betel or any other source, both individually or in a synergistic combination optionally along with pharmaceutically acceptable additives.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water: methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination, and a composition comprising the said fraction nos. 1 and 9.