Patents by Inventor Samir Bouzbouz

Samir Bouzbouz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metalloprotease inhibitors, methods for producing same, and therapeutics uses thereof
    Patent number: 9682929
    Abstract: The invention relates to new ?-vinyl carbonylated compounds corresponding to general formula (I), wherein R1, R2,R3, R4, R5 and Y are as defined in claim 1, their isomers, their diastereoisomers and acid addition salts or a pharmaceutically acceptable base. The invention also relates to a method for producing said compounds (I). It further relates to the use of said compound (I) as selective metalloprotease inhibitors, especially matrix metalloproteases 12 (MMP-12) and/or 9 (MMP-9). The compounds (I) are particularly useful for the prevention and/or treatment of chronic obstructive pulmonary disease (COPD), particularly emphysema induced by cigarette smoke.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: June 20, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE
    Inventors: Samir Bouzbouz, Xavier Pannecoucke, Azzaq Belaaouaj, Laurette Malleret, Clement Denhez, Dominique Guillaume
  • METALLOPROTEASE INHIBITORS, METHODS FOR PRODUCING SAME, AND THERAPEUTIC USES THEREOF
    Publication number: 20160200676
    Abstract: The invention relates to new ?-vinyl carbonylated compounds corresponding to general formula (I), wherein R1, R2, R3, R4, R5 and Y are as defined in claim 1, their isomers, their diastereoisomers and acid addition salts or a pharmaceutically acceptable base. The invention also relates to a method for producing said compounds (I). It further relates to the use of said compounds (I) as selective metalloprotease inhibitors, especially matrix metalloproteases 12 (MMP-12) and/or 9 (MMP-9). The compounds (I) are particularly useful for the prevention and/or treatment of chronic obstructive pulmonary disease (COPD), particularly emphysema induced by cigarette smoke.
    Type: Application
    Filed: September 2, 2014
    Publication date: July 14, 2016
    Applicant: Universite de Reims Champagne-Ardenne
    Inventors: Samir Bouzbouz, Xavier Pannecoucke, Azzaq Belaaouaj, Laurette Malleret, Clement Denhez, Dominique Guillaume