Abstract: A novel transgene for use to produce a coronavirus vaccine is provided. The transgene encodes: i) an RNA polymerase promoter; ii) a 5? UTR; iii) a secretory sequence; iv) a coronavirus spike protein component, wherein the spike protein component incorporates a variant sequence at amino acid position 614 of a native spike protein; and v) a 3? UTR and poly A sequence. A vaccine is also provided comprising the transgene or an mRNA transcript thereof.

Abstract: Systems and methods are directed to predicting temporal startup measurements using a machine-trained model. The system determines a training dataset of features associated with different funding, exit, and closure events and corresponding times of the funding, exit, and closure events from historical financial data. A temporal prediction model is trained using the training dataset. The temporal prediction model can comprise a recurrent neural network (e.g., gated recurrent unit). During runtime, the system accesses new data associated with potential future investment opportunities with startups and determines (e.g., compute) company features based, in part, on the new data. The system applies the company features to the temporal prediction model to simultaneously predict a next event and a time of the next event for each startup. A user interface can then be presented that shows the predicted next event and the predicted time of the predicted next event for each startup.

Abstract: Systems and methods are directed to predicting temporal startup measurements using a machine-trained model. The system determines a training dataset of features associated with different funding, exit, and closure events and corresponding times of the funding, exit, and closure events from historical financial data. A temporal prediction model is trained using the training dataset. The temporal prediction model can comprise a recurrent neural network (e.g., gated recurrent unit). During runtime, the system accesses new data associated with potential future investment opportunities with startups and determines (e.g., compute) company features based, in part, on the new data. The system applies the company features to the temporal prediction model to simultaneously predict a next event and a time of the next event for each startup. A user interface can then be presented that shows the predicted next event and the predicted time of the predicted next event for each startup.

Abstract: The invention provides a process for preparing core-shell composite particles comprising a polyester, polymerized ethylenically unsaturated silane compounds, and optionally a hydrophobic surface treatment. The invention further provides a composite particle comprising a polyester and a radically polymerized ethylenically unsaturated silane compound.

Abstract: A novel transgene for use to produce a coronavirus vaccine is provided. The transgene encodes: i) an RNA polymerase promoter; ii) a 5? UTR; iii) a secretory sequence; iv) a coronavirus spike protein component, wherein the spike protein component incorporates a variant sequence at amino acid position 614 of a native spike protein; and v) a 3? UTR and poly A sequence. A vaccine is also provided comprising the transgene or an mRNA transcript thereof.

Abstract: The invention provides a process for preparing core-shell composite particles comprising a polyester, polymerized ethylenically unsaturated silane compounds, and optionally a hydrophobic surface treatment. The invention further provides a composite particle comprising a polyester and a radically polymerized ethylenically unsaturated silane compound.

Abstract: The invention provides a process for preparing core-shell composite particles comprising a polyester, polymerized ethylenically unsaturated silane compounds, and optionally a hydrophobic surface treatment. The invention further provides a composite particle comprising a polyester and a radically polymerized ethylenically unsaturated silane compound.

Abstract: The invention provides a process for preparing core-shell composite particles comprising a polyester, polymerized ethylenically unsaturated silane compounds, and optionally a hydrophobic surface treatment. The invention further provides a composite particle comprising a polyester and a radically polymerized ethylenically unsaturated silane compound.

Abstract: Various embodiments of a system and method for authoritative item identification based on facility operations are described. Embodiments may include an authoritative item identification component configured to, for each particular item of multiple items in inventory of a materials handling facility, determine multiple identifiers for the particular item, where one or more of the multiple identifiers are electronically obtained from a unit of the particular item during operations of the materials handling facility. The authoritative item identification component may, for each of the multiple identifiers, determine a quantity of instances in which that identifier was electronically obtained from a given unit of the particular item. The authoritative item identification component may, based on a statistical analysis of the quantities, determine one of the multiple identifiers as being an authoritative identifier for the particular item.

Abstract: Methods, systems and devices for generating data models in a client-cloud communication system may include applying machine learning techniques to generate a first family of classifier models that describe a cloud corpus of behavior vectors. Such vectors may be analyzed to identify factors in the first family of classifier models that have the highest probability of enabling a mobile device to better determine whether a mobile device behavior is malicious or benign. Based on this analysis, a second family of classifier models may be generated that identify significantly fewer factors and data points as being relevant for enabling the mobile device to better determine whether the mobile device behavior is malicious or benign based on the determined factors. A mobile device classifier module based on the second family of classifier models may be generated and made available for download by mobile devices, including devices contributing behavior vectors.

Abstract: A cleaning blade lubricant including an acicular shape lubricant is provided. The cleaning blade lubricant is applied to a cleaning blade of an electrophotographic printing device for improving the cleaning performance of a cleaning blade of an electrophotographic printing device.

Abstract: A two component development system includes a plurality of toner particles that include a colorant and a plurality of toner carrier particles that include a magnetic carrier core having a D50 diameter in a range from about 30 microns to about 40 microns, and a surfactant-polymer coating, the coating being present in an amount in a range from about 0.5 percent by weight to about 1.5 percent by weight of the toner carrier particle.

Abstract: A process includes forming, by emulsion polymerization, polymer resin particles in a latex, the polymer resin particles being formed from a mixture including one or more monomer emulsions and a non-surfactant-based charge control agent, the emulsion polymerization is carried out with a solids content in a range from about 10 to about 30 percent by weight of the mixture, and forming toner particles from the polymer resin particles, the toner particles support a sufficient triboelectric charge for use under A-zone environmental conditions in a single-component development system.

Abstract: A toner composition with a novel surface additive package for developing images is provided. The additive package comprises a sol-gel silica, a PDMS silica, an HMDS silica, and an organic spacer such as PMMA, and melamine. The toner composition exhibits improved properties and are useful for high speed printing on Single Component Development systems.

Abstract: Hyperpigmented magenta toner, that is indistinguishable from standard and conventional magenta toner, contains PR122 and PR260 in a 56:44 weight ratio and can be used with reduced TMA as compared to conventional magenta toner.

Abstract: Emulsion aggregation toner comprising: a resin; a wax; a colorant; an encapsulating shell; and a silica external additive comprising: first silica particles comprising fumed silica particles surface treated with octyldimethylsiloxane and having average particle diameter about 6-20 nm, present in amount of about 0.1-1% by weight of the toner; second silica particles comprising colloidal silica particles surface treated with hexamethyldisiloxane and having average particle diameter about 80-200 nm, present in amount of about 1-2% by weight of the toner; third silica particles comprising fumed silica particles surface treated with polydimethylsiloxane and having average particle diameter about 25-65 nm, present in amount of from about 0.5-1.5% by weight of the toner; and fourth silica particles comprising fumed silica particles surface treated with hexamethyldisiloxane and having average particle diameter about 25-65 nm, present in amount of about 1-2.5% by weight of the toner.

Abstract: Toner compositions that having spherical particles and provide stable density. The toner compositions also comprise and deliver a silicone oil to the cleaning subsystem in the image forming apparatus by incorporating an inorganic fine powder additive package that has been mixed with silicone oil in a manner such that the toner is blended with the inorganic fine powder and silicone oil.

Abstract: A toner composition includes a resin, optionally a wax, a colorant, and an acicular surface additive. The toner composition is suitable for use in a single component development system and which composition possesses excellent charging, stability, and flow characteristics.

Abstract: Toner compositions that having spherical particles and provide stable density. The toner compositions also comprise and deliver a silicone oil to the cleaning subsystem in the image forming apparatus by incorporating an inorganic fine powder additive package that has been mixed with silicone oil in a manner such that the toner is blended with the inorganic fine powder and silicone oil.

Abstract: A process includes forming, by emulsion polymerization, polymer resin particles in a latex, the polymer resin particles being formed from a mixture including one or more monomer emulsions and a non-surfactant-based charge control agent, the emulsion polymerization is carried out with a solids content in a range from about 10 to about 30 percent by weight of the mixture, and forming toner particles from the polymer resin particles, the toner particles support a sufficient triboelectric charge for use under A-zone environmental conditions in a single-component development system.