Patents by Inventor Samir M. Parikh

Samir M. Parikh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Niacinamide (NAM) in ischemic tissue injury
    Patent number: 11116784
    Abstract: Methods of treating ischemic tissue injury or kidney disease, e.g., delayed graft function, that include administering a Nicotinamide adenine dinucleotide (NAD)/niacinamide (NAM) pathway agonist.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: September 14, 2021
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventor: Samir M. Parikh
  • NIACINAMIDE (NAM) IN ISCHEMIC TISSUE INJURY
    Publication number: 20190070211
    Abstract: Methods of treating ischemic tissue injury or kidney disease, e.g., delayed graft function, that include administering a Nicotinamide adenine dinucleotide (NAD)/niacinamide (NAM) pathway agonist.
    Type: Application
    Filed: February 21, 2017
    Publication date: March 7, 2019
    Inventor: Samir M. Parikh
  • METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF DISEASES CHARACTERIZED BY VASCULAR LEAK, HYPOTENSION, OR A PROCOAGULANT STATE
    Publication number: 20160185845
    Abstract: Disclosed herein are methods for treating a vascular leak disorder, hypotension, or a procoagulant state using angiopoietin-2 (Ang-2) antagonist compounds. Also disclosed are methods for treating a vascular leak disorder associated with high dose IL-2 therapy using angiopoietin-2 antagonist compounds. Methods for diagnosing and monitoring vascular leak disorders, hypotension, or a procoagulant state that include the measurement of Ang-2 polypeptide or nucleic acid levels are also disclosed. Methods for inducing a vascular leak using an Ang-2 agonist are also disclosed.
    Type: Application
    Filed: August 14, 2014
    Publication date: June 30, 2016
    Inventors: Vikas P. Sukhatme, S. Ananth Karumanchi, Samir M. Parikh
  • Methods and compositions for the treatment and diagnosis of systemic anthrax infection
    Patent number: 8685393
    Abstract: The present invention features methods and kits that utilize Ang-2 antagonists for the treatment, inhibition, and prevention of a systemic anthrax infection. The invention described herein also features methods for the diagnosis of a systemic anthrax infection by detecting elevated levels of Ang-2 in the serum of a subject.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: April 1, 2014
    Assignee: Beth Israel Deaconess Medical Center
    Inventor: Samir M. Parikh
  • METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF DISEASES CHARACTERIZED BY VASCULAR LEAK, HYPOTENSION, OR A PROCOAGULANT STATE
    Publication number: 20130252821
    Abstract: Disclosed herein are methods for treating a vascular leak disorder, hypotension, or a procoagulant state using angiopoietin-2 (Ang-2) antagonist compounds. Also disclosed are methods for treating a vascular leak disorder associated with high dose IL-2 therapy using angiopoietin-2 antagonist compounds. Methods for diagnosing and monitoring vascular leak disorders, hypotension, or a procoagulant state that include the measurement of Ang-2 polypeptide or nucleic acid levels are also disclosed. Methods for inducing a vascular leak using an Ang-2 agonist are also disclosed.
    Type: Application
    Filed: September 10, 2012
    Publication date: September 26, 2013
    Applicant: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Vikas P. Sukhatme, S. Ananth Karumanchi, Samir M. Parikh
  • METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF SYSTEMIC ANTHRAX INFECTION
    Publication number: 20110110939
    Abstract: The present invention features methods and kits that utilize Ang-2 antagonists for the treatment, inhibition, and prevention of a systemic anthrax infection. The invention described herein also features methods for the diagnosis of a systemic anthrax infection by detecting elevated levels of Ang-2 in the serum of a subject.
    Type: Application
    Filed: March 23, 2009
    Publication date: May 12, 2011
    Inventor: Samir M. Parikh
  • METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF DISEASES CHARACTERIZED BY VASCULAR LEAK, HYPOTENSION, OR A PROCOAGULANT STATE
    Publication number: 20100221243
    Abstract: Disclosed herein are methods for treating a vascular leak disorder, hypotension, or a procoagulant state using angiopoietin-2 (Ang-2) antagonist compounds. Also disclosed are methods for treating a vascular leak disorder associated with high dose IL-2 therapy using angiopoietin-2 antagonist compounds. Methods for diagnosing and monitoring vascular leak disorders, hypotension, or a procoagulant state that include the measurement of Ang-2 polypeptide or nucleic acid levels are also disclosed. Methods for inducing a vascular leak using an Ang-2 agonist are also disclosed.
    Type: Application
    Filed: January 26, 2009
    Publication date: September 2, 2010
    Applicant: Beth Israel Deaconess Medical Center
    Inventors: Vikas P. Sukhatme, S. Ananth Karumanchi, Samir M. Parikh