Abstract: A system configured to receive health data pertaining to a user; select a user health profile from a plurality of user health profiles based on the collected health data, each of the plurality of user health profiles being associated with a health and wellness program and a set of interventions; receive user activity data and updated health data pertaining to, or during the user's participation in the associated health and wellness program from health devices; select a new set of interventions based on the user activity data; and select a new user health profile from the plurality of user health profiles based on at least one of the user activity data and the updated health data.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-05 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: A system and method of unloading a heart chamber is described. The chamber can be a ventricle and the system can unload the ventricle during or after a heart attack. The ventricular unloading system includes a transthoracic needle insertable into the ventricle, a vascular access cannula insertable into a blood vessel, and a pump to move blood from the ventricle to the blood vessel through the transthoracic needle and the vascular access cannula. The ventricular unloading system can be used by an emergency medical technician in a non-hospital setting. Accordingly, the ventricular unloading system can provide early protection against infarct to improve clinical outcomes for a patient. Other embodiments are also described and claimed.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: Systems and methods for biomonitoring and personalized healthcare are disclosed herein. In some embodiments, a biomonitoring and healthcare guidance system is configured to generate personalized self-care recommendations (e.g., recommendations relating to sleep, exercise, diet, etc.) to guide a. patient in effectively managing and/or improving a chronic condition (e.g., diabetes, pre-diabetes, hypertension, hyperlipidemia, etc.). The system can continuously or periodically update and/or adapt the self-care recommendations (e.g., based on data from the particular patient as well as data from a plurality of other patients). The system can guide individuals toward self-care changes that are likely to improve their chronic health conditions, support them in making those changes, and adapt and/or update continuously over time.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: Incident capture systems and methods for a vehicle. One example system includes a head unit that displays a user interface to view and manage incident images. The system also includes an existing vehicle sensor configured to sense conditions outside of the vehicle, an existing vehicle camera configured to capture conditions outside of the vehicle, and an electronic controller. The electronic controller is configured to detect a change in the conditions outside of the vehicle from the existing sensor; determine a state of the system, wherein the state of the system is one selected from the group consisting of an on state and an off state; and in response to determining an on state, receive at least one image from the existing vehicle camera; and store the at least one image in a stack located in a non-transitory computer-readable storage medium.

Abstract: Incident capture systems and methods for a vehicle. One example system includes a head unit that displays a user interface to view and manage incident images. The system also includes an existing vehicle sensor configured to sense conditions outside of the vehicle, an existing vehicle camera configured to capture conditions outside of the vehicle, and an electronic controller. The electronic controller is configured to detect a change in the conditions outside of the vehicle from the existing sensor; determine a state of the system, wherein the state of the system is one selected from the group consisting of an on state and an off state; and in response to determining an on state, receive at least one image from the existing vehicle camera; and store the at least one image in a stack located in a non-transitory computer-readable storage medium.

Abstract: Embodiments of the disclosure enable contextual user experiences to be provided. A computing system receives sensor data from an appliance associated with a first user account, and analyzes the sensor data to identify a product and one or more second user accounts associated with the product. The second user accounts are used to aggregate product data associated with the product, and the product data is used to generate catalog data associated with the product. The catalog data includes one or more portions associated with the second user accounts and is transmitted to a client device associated with the first user account to prompt a first user to enter into a transaction associated with the product. Each portion of the catalog data is selectable to facilitate the transaction between the first user and a respective second user associated with the second user accounts.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: Embodiments of the disclosure enable contextual user experiences to be provided. A computing system receives sensor data from an appliance associated with a first user account, and analyzes the sensor data to identify a product and one or more second user accounts associated with the product. The second user accounts are used to aggregate product data associated with the product, and the product data is used to generate catalog data associated with the product. The catalog data includes one or more portions associated with the second user accounts and is transmitted to a client device associated with the first user account to prompt a first user to enter into a transaction associated with the product. Each portion of the catalog data is selectable to facilitate the transaction between the first user and a respective second user associated with the second user accounts.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: This invention relates to methods and compositions useful for the treatment or prevention of an ophthalmological disease, comprising administration of an effective amount of a PDGF antagonist and a VEGF antagonist to a mammal in need thereof.

Abstract: The present invention relates to the new impurities of Fesoterodine, Fesoterodine symmetric dimer impurity and asymmetric dimer impurity, process for preparing and isolating thereof. The invention also deals with analytical standards and analytical methods used for the control of the production process and final quality of Fesoterodine.

Abstract: A device and a method are disclosed for replaceably insulating a roof of an industrial oven that allows repair of damaged insulation while the oven continues operation at high temperatures.

Abstract: The present invention relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering Antagonist A or another pharmaceutically acceptable salt thereof, optionally in combination with another treatment, to a subject in need thereof. The present invention also relates to methods for treating and preventing ophthalmological disease and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in combination with another treatment, to a subject in need thereof.

Abstract: The present invention relates to an improved process for the preparation of Fesoterodine and pharmaceutically acceptable salts thereof. The present invention particularly relates to a process for the preparation of fesoterodine and pharmaceutically acceptable salts thereof which involves use and preparation of R(+)benzyl tolterodine and fumarate salt of R(+)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol.