Patents by Inventor Samir Ross

Samir Ross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7767655
    Abstract: A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipients. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercial Aloe products.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: August 3, 2010
    Assignee: University of Mississippi
    Inventors: David Stanley Pasco, Nirmal Derek Pugh, Mahmoud Elsohly, Samir Ross
  • Publication number: 20070286914
    Abstract: A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipents. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercial Aloe products.
    Type: Application
    Filed: January 12, 2007
    Publication date: December 13, 2007
    Applicant: The University of Mississippi
    Inventors: David Pasco, Nirmal Pugh, Mahmoud Elsohly, Samir Ross
  • Publication number: 20070264271
    Abstract: Immunostimulatory polysaccharides can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent immunostimulatory activity. The preferential extraction of these immunostimulatory polysaccharides is dependent on the concentration of ethanol used and the extraction temperature. The most efficient conditions are 50% ethanol concentration at temperatures between 60° and 70° C. The isolated polysaccharide preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function.
    Type: Application
    Filed: April 5, 2007
    Publication date: November 15, 2007
    Applicant: The University of Mississippi
    Inventors: Mahmoud ElSohly, Samir Ross, David Pasco, Nirmal Pugh, Hala ElSohly
  • Patent number: 7205284
    Abstract: Immunostimulatory polysaccharides can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent immunostimulatory activity. The preferential extraction of these immunostimulatory polysaccharides is dependent on the concentration of ethanol used and the extraction temperature. The most efficient conditions are 50% ethanol concentration at temperatures between 60° and 70° C. The isolated polysaccharide preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: April 17, 2007
    Assignee: University of Mississippi
    Inventors: David Stanley Pasco, Nirmal Derek Pugh, Mahmoud ElSohly, Samir Ross, Nala Miazi ElSohly
  • Patent number: 7196072
    Abstract: A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipents. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercial Aloe products.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: March 27, 2007
    Assignee: University of Mississippi
    Inventors: David Stanley Pasco, Nirmal Derek Ceri Pugh, Mahmoud ElSohly, Samir Ross
  • Publication number: 20070059317
    Abstract: Immunostimulatory polysaccharides can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent immunostimulatory activity. The preferential extraction of these immunostimulatory polysaccharides is dependent on the concentration of ethanol used and the extraction temperature. The most efficient conditions are 50% ethanol concentration at temperatures between 60° and 70° C. The isolated polysaccharide preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function.
    Type: Application
    Filed: July 10, 2001
    Publication date: March 15, 2007
    Inventors: Mahmoud ElSohly, Samir Ross, David Pasco, Nirmal Pugh, Hala ElSohly
  • Patent number: 7098242
    Abstract: This invention comprises compositions containing dihydroartemisinin and dihydroartemisitene dimers with activity as anticancer agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer, and protozoal infections, including malaria, or leishmaniasis. The compounds of this invention represent a potential new class of anti-tumor agents, one that has shown promising activity against solid tumors, and with a pattern of selectivity that suggests a possible new mechanism of action.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: August 29, 2006
    Assignee: The University of Mississippi
    Inventors: Mahmoud A. ElSohly, Samir A. Ross, Ahmed M. Galal
  • Publication number: 20040266860
    Abstract: This invention comprises compositions containing dihydroartemisinin and dihydroartemisitene dimers with activity as anticancer agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer, and protozoal infections, including malaria, or leishmaniasis.
    Type: Application
    Filed: July 21, 2004
    Publication date: December 30, 2004
    Inventors: Mahmoud A. ElSohly, Samir A. Ross, Ahmed M. Galal
  • Publication number: 20040229938
    Abstract: This invention comprises compositions containing dihydroartemisinin and dihydroartemisitene dimers with activity as anticancer agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer, and protozoal infections, including malaria, or leishmaniasis.
    Type: Application
    Filed: June 21, 2004
    Publication date: November 18, 2004
    Inventors: Mahmoud A. ElSohly, Samir A. Ross, Ahmed M. Galal
  • Patent number: 6790863
    Abstract: This invention comprises compositions containing dihydroartemisinin and dihydroartemisitene dimers with activity as anticancer agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer, and protozoal infections, including malaria, or leishmaniasis. The compounds of this invention represent a potential new class of anti-tumor agents, one that has shown promising activity against solid tumors, and with a pattern of selectivity that suggests a possible new mechanism of action.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 14, 2004
    Assignee: University of Mississippi
    Inventors: Mahmoud A. ElSohly, Samir A. Ross, Ahmed M. Galal
  • Patent number: 6730519
    Abstract: A method for the isolation of delta-9-tetrahydrocannibinol (THC) from, Cannabis plant material, wherein delta-9-THC Acid and THC are separately obtained including the steps of extracting the Cannabis plant material, chelating delta-9-THC acid on alumina solid support from cannabis extracts rich in the acid washing of non-acid components of the extract with organic solvents and eluting of the delta-9-THC acid with strong polar solvents.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: May 4, 2004
    Assignee: The University of Mississippi
    Inventors: Mahmoud A. Elsohly, Samir A. Ross
  • Publication number: 20040072896
    Abstract: This invention relates to a compound of the formula 1
    Type: Application
    Filed: October 15, 2002
    Publication date: April 15, 2004
    Inventors: Mahmoud A. ElSohly, Samir A. Ross, Ahmed M. Galal
  • Publication number: 20040038931
    Abstract: A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipents. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercial Aloe products.
    Type: Application
    Filed: August 13, 2003
    Publication date: February 26, 2004
    Inventors: Mahmoud Elsobly, Samir Ross, David Stanley Pasco, Nirmal Derek Pugh
  • Publication number: 20020086438
    Abstract: A method for the isolation of delta-9-tetrahydrocannibinol (THC) from, Cannabis plant material, wherein delta-9-THC Acid and THC are separately obtained comprising the steps of extracting the Cannabis plant material, chelating delta-9-THC acid on alumina solid support from cannabis extracts rich in the acid washing of non-acid components of the extract with organic solvents and eluting of the delta-9-THC acid with strong polar solvents.
    Type: Application
    Filed: December 4, 2001
    Publication date: July 4, 2002
    Inventors: Mahmoud A. Elsohly, Samir A. Ross
  • Publication number: 20020039795
    Abstract: A method of preparing tetrahydrocannabinol using extraction of plant material with a non-polar solvent followed by vacuum distillation and collection of a constant boiling fraction. Additional distillation steps and chromatographic steps, including HPLC reversed phase HPLC and flash chromatography, may be performed.
    Type: Application
    Filed: October 26, 1998
    Publication date: April 4, 2002
    Applicant: Elsohly Et Al
    Inventors: MAHMOUD A. ELSOHLY, SAMIR A. ROSS
  • Patent number: 6365416
    Abstract: A method of preparing THC using extraction of plant material with a non-polar solvent followed by vacuum distillation and chromatography.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: April 2, 2002
    Assignee: The University of Mississippi
    Inventors: Mahmoud A. Elsohly, Samir A. Ross
  • Patent number: 6008383
    Abstract: The present invention provides an economical and efficient process for converting delta-9-tetrahydrocannabinol to a variety of ester analogs. Delta-9-tetrahydrocannabinol is esterified by reaction with a carboxylic acid, an acid halide or an acid anhydride in the presence of a 4-aminopyridine either alone or in admixture with an organic amine such as a mono-, di-, or tri-alkyl amine.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: December 28, 1999
    Assignee: University of Mississippi
    Inventors: Mahmoud A. Elsohly, Samir A. Ross, Shixia Feng