Patents by Inventor Samit Ghosh

Samit Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Heme Oxygenase-1 (HO-1) for the Treatment of Sickle Cell Disease
    Publication number: 20230018417
    Abstract: The present invention provides, among other things, methods and compositions for making and using recombinant heme oxygenase for treating sickle cell disease. In some embodiments, recombinant heme oxygenase proteins are truncation variants, or Fc fusion proteins with increased half-life and/or reduced aggregation.
    Type: Application
    Filed: July 24, 2020
    Publication date: January 19, 2023
    Inventors: Solomon Fiifi Ofori-Acquah, Samit Ghosh, Joseph Sypek, Bohong Zhang, Xiuxia Sun, Clark Q. Pan, Daniel Minard Lajole, Chuan Shen
  • METHODS OF TREATING AND DIAGNOSING ACUTE CHEST SYNDROME
    Publication number: 20130123185
    Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing organ inflammation or failure such as pulmonary inflammation comprising administering a heme scavenger such as hemopexin to a subject in need thereof. The subject may be diagnosed with higher than normal levels of protein-free plasma heme or a hemolytic disorder such as sickle cell disease, autoimmune hemolytic anemia, or paroxysmal nocturnal hemoglobinuria or acute lung injury or acute chest syndrome. Typically, the hemopexin is recombinant human hemopexin.
    Type: Application
    Filed: August 5, 2011
    Publication date: May 16, 2013
    Applicant: EMORY UNIVERSITY
    Inventors: Solomon Ofori-Acquah, Samit Ghosh