Patents by Inventor Samit S. Mehta

Samit S. Mehta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fingolimod hydrochloride process
    Patent number: 9643914
    Abstract: A process for preparation of diethyl 2-aetamido-2-(4-octyl phenyl)ethyl malonate (III), a key intermediate of fingolimod hydrochloride comprising reaction of 2-(4-octylphenyl)ethyl iodide (IV) with diethyl acetamido malonate in presence of a base and an iodinating agent and in an organic solvent. The compound of formula (III) thus obtained provided fingolimod hydrochloride (Ia) having associated impurities below the regulatory limits.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: May 9, 2017
    Assignee: EMCURE PHARMACEUTICALS LIMITED
    Inventors: Mukund K. Gurjar, Narendra K. Tripathy, Kaliaperumal Neelakandan, Prasad P. Panchabhai, Nandala Srinivas, Prabhakaran Balasubramanian, Sandip B. Buchude, Balaji R. Mugale, Pravin P. Ahirrao, Samit S. Mehta
  • FINGOLIMOD HYDROCHLORIDE PROCESS
    Publication number: 20160289166
    Abstract: A process for preparation of diethyl 2-aetamido-2-(4-octyl phenyl)ethyl malonate (III), a key intermediate of fingolimod hydrochloride comprising reaction of 2-(4-octylphenyl)ethyl iodide (IV) with diethyl acetamido malonate in presence of a base and an iodinating agent and in an organic solvent. The compound of formula (III) thus obtained provided fingolimod hydrochloride (Ia) having associated impurities below the regulatory limits.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 6, 2016
    Inventors: Mukund K. GURJAR, Narendra K. THIPATHY, Kaliaperumal NEELAKANDAN, Prasad P. PANCHABHAI, Nandala SRINIVAS, Prabhakaran BALASUBRAMANIAN, Sandip B. BUCHUDE, Balaji R. MUGALE, Pravin P. AHIRRAO, Samit S. MEHTA
  • Process for preparation of taxane derivatives
    Patent number: 8686165
    Abstract: The present disclosure relates to processes for the preparation of taxane derivatives with improved purity and enhanced stability. The taxane derivatives prepared according to the processes described herein are useful for the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: April 1, 2014
    Assignee: Emcure Pharmaceuticals Limited
    Inventors: Mukund K. Gurjar, Swapnil P. Sonawane, Pankaj S. Patil, Samit S. Mehta
  • Process for Preparation of Taxane Derivatives
    Publication number: 20110105598
    Abstract: The present disclosure relates to processes for the preparation of taxane derivatives with improved purity and enhanced stability. The taxane derivatives prepared according to the processes described herein are useful for the preparation of pharmaceutical compositions.
    Type: Application
    Filed: November 2, 2010
    Publication date: May 5, 2011
    Applicant: Emcure Pharmaceuticals Limited
    Inventors: Mukund K. GURJAR, Swapnil P. SONAWANE, Pankaj S. PATIL, Samit S. MEHTA
  • PROCESS FOR PREPARATION OF BENZPHETAMINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20110046416
    Abstract: The present invention provides a simple method for preparation of benzphetamine and its acid addition salt comprising reaction of methamphetamine hydrochloride of formula (III) with benzyl chloride and treating the isolated benzphetamine of formula (II) with an acid dissolved in an organic solvent to provide benzphetamine acid addition salt, more specifically, benzphetamine hydrochloride of formula (I).
    Type: Application
    Filed: August 18, 2010
    Publication date: February 24, 2011
    Applicant: Emcure Pharmaceuticals Limited
    Inventors: Mukund K. Gurjar, Narendra K. Tripathy, Kiran A. Bapat, Vemavarapu P.K.V. Rao, Satyjeet B. Biswas, Samit S. Mehta