Patents by Inventor Sampath Kumar Anandan

Sampath Kumar Anandan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPIOID AGONIST PEPTIDES AND USES THEREOF
    Publication number: 20190076400
    Abstract: The invention is directed to opioid agonist peptides and their use.
    Type: Application
    Filed: September 11, 2018
    Publication date: March 14, 2019
    Inventors: Sampath Kumar Anandan, Jie Zhang, Ashok Bhandari, Gregory Thomas Bourne, Brian Troy Frederick, Larry C. Mattheakis, David Liu
  • METHODS FOR SYNTHESIZING alpha4ß7 PEPTIDE ANTAGONISTS
    Publication number: 20170327541
    Abstract: The present invention provides methods of making ?4?7 peptide monmer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.
    Type: Application
    Filed: March 23, 2017
    Publication date: November 16, 2017
    Inventors: Ashok Bhandari, Suresh Kumar Manthati, Mukund M. Mehrotra, Sampath-Kumar Anandan, Dinesh V. Patel
  • 2?-ethynyl nucleoside derivatives for treatment of viral infections
    Patent number: 9814739
    Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: November 14, 2017
    Assignee: Novartis AG
    Inventors: Sampath-Kumar Anandan, Virender Singh Aulakh, Martijn Fenaux, Xiaodong Lin, Liang Mao, Oliver Saunders, Zachary Kevin Sweeney, Fumiaki Yokokawa, Weidong Zhong
  • 2'-Ethynyl Nucleoside Derivatives for Treatment of Viral Infections
    Publication number: 20170112868
    Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.
    Type: Application
    Filed: December 14, 2016
    Publication date: April 27, 2017
    Inventors: Sampath-Kumar Anandan, Virender Singh Aulakh, Martijn Fenaux, Xiaodong Lin, Liang Mao, Oliver Saunders, Zachary Kevin Sweeney, Fumiaki Yokokawa, Weidong Zhong
  • 2?-Ethynyl nucleoside derivatives for treatment of viral infections
    Patent number: 9556216
    Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are as defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue fever, yellow fever, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: January 31, 2017
    Assignee: Novartis AG
    Inventors: Sampath-Kumar Anandan, Virender Singh Aulakh, Martijn Fenaux, Xiaodong Lin, Liang Mao, Oliver Saunders, Zachary Kevin Sweeney, Fumiaki Yokokawa, Weidong Zhong
  • Soluble epoxide hydrolase inhibitors
    Publication number: 20090270382
    Abstract: Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetic-related diseases.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 29, 2009
    Inventors: Bhasker R. Aavula, Sampath-Kumar Anandan, Richard D. Gless, JR.
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION
    Publication number: 20090247521
    Abstract: The present invention generally relates to methods useful for a therapy using a class of urea or amide compounds and related compositions, wherein the compound is a soluble epoxide hydrolase inhibitor, for treating and ameliorating the symptoms of diseases related to endothelial dysfunction.
    Type: Application
    Filed: December 23, 2008
    Publication date: October 1, 2009
    Inventors: Bhasker R. Aavula, Sampath-Kumar Anandan, Richard D. Gless, JR., Dinesh Patel, Gabor Rubanyi, Yi-Xin Wang, Heather K. Webb Hsu
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20090082423
    Abstract: Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetic-related diseases.
    Type: Application
    Filed: September 10, 2008
    Publication date: March 26, 2009
    Inventors: Sampath-Kumar Anandan, Richard D. Gless, JR.
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20090082350
    Abstract: Disclosed are heterocylic or heteroaryl compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
    Type: Application
    Filed: September 10, 2008
    Publication date: March 26, 2009
    Inventors: Sampath-Kumar Anandan, Richard D. Gless, JR.
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20090023731
    Abstract: Disclosed are urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetic-related diseases.
    Type: Application
    Filed: March 21, 2008
    Publication date: January 22, 2009
    Inventors: Richard D. Gless, JR., Sampath Kumar Anandan
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080227780
    Abstract: Disclosed are urea compounds, stereoisomer, or pharmaceutical acceptable salt thereof, and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
    Type: Application
    Filed: October 19, 2007
    Publication date: September 18, 2008
    Inventors: Richard D. Gless, Sampath Kumar Anandan, Bhaskar R. Aavula
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080221100
    Abstract: Disclosed are urea compounds, stereoisomer, or pharmaceutical acceptable salt thereof, and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
    Type: Application
    Filed: October 19, 2007
    Publication date: September 11, 2008
    Inventors: Richard D. Gless, Sampath Kumar Anandan, Bhaskar R. Aavula
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080200467
    Abstract: Disclosed are alpha keto amide and alpha hydroxy amide compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
    Type: Application
    Filed: November 2, 2007
    Publication date: August 21, 2008
    Inventors: Dinesh Patel, Richard D. Gless, Heather K. Webb Hsu, Sampath Kumar Anandan, Bhaskar R. Aavula
  • SOLUBLE EPOXIDE HYDROLASE INHIBITORS
    Publication number: 20080200444
    Abstract: Disclosed are urea compounds of formula I, stereoisomer, or pharmaceutical acceptable salts thereof, and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
    Type: Application
    Filed: October 19, 2007
    Publication date: August 21, 2008
    Inventors: Richard D. Gless, Sampath Kumar Anandan
  • Lincomycin derivatives possessing antimicrobial activity
    Patent number: 7199106
    Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: April 3, 2007
    Assignee: Vicuron Pharmaceuticals, Inc.
    Inventors: Jason G. Lewis, Sampath-Kumar Anandan, Hardwin O'Dowd, Mikhail F. Gordeev
  • Lincomycin derivatives possessing antibacterial activity
    Patent number: 7199105
    Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: April 3, 2007
    Assignee: Vicuron Pharmaceuticals, Inc.
    Inventors: Jason G. Lewis, Dinesh V. Patel, Sampath Kumar Anandan, Mikhail F. Gordeev
  • Novel lincomycin derivatives possessing antimicrobial activity
    Publication number: 20050043248
    Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
    Type: Application
    Filed: June 17, 2004
    Publication date: February 24, 2005
    Inventors: Jason Lewis, Sampath-Kumar Anandan, Hardwin O'Dowd, Mikhail Gordeev
  • Lincomycin derivatives possessing antibacterial activity
    Publication number: 20040230046
    Abstract: Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
    Type: Application
    Filed: February 11, 2004
    Publication date: November 18, 2004
    Applicant: VICURON PHARMACEUTICALS INC.
    Inventors: Jason G. Lewis, Dinesh V. Patel, Sampath Kumar Anandan, Mikhail F. Gordeev