Patents by Inventor Samuel A. Burstein

Samuel A. Burstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-gp130 monoclonal antibodies
    Patent number: 5571513
    Abstract: Anti-gp130 monoclonal antibodies (Mabs) obtained from hybridomas designated 4B11 and 2H4 are effective in the inhibition of the acute phase response on hepatoma cells and prevent the IL-6-induced growth inhibition of A375 cells in vitro. Administration of the antibodies to dogs showed that 2H4 is a potent in vivo inhibitor of the IL-6-induced acute phase response, abrogating IL-6-mediated-increments in fibrinogen, C-reactive protein and the platelet count. Antibodies may be used in methods for measuring soluble gp130 and in therapeutic treatments. The 2H4 antibody may be used in inhibiting in vivo the function of gp130 or cellular factors dependent on gp130 for cellular transduction.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 5, 1996
    Assignee: The Board Of Regents Of The University Of Oklahoma
    Inventor: Samuel A. Burstein
  • Enhancing growth of megakaryocytes in mammals using interleukin 6
    Patent number: 5178856
    Abstract: A therapeutic method for treating mammals by administering an effective dosage of a substance comprising interleukin 6 and interleukin 3 into the mammal for enhancing the growth of megakaryocytes and platelets.
    Type: Grant
    Filed: May 15, 1991
    Date of Patent: January 12, 1993
    Assignee: Board of Regents of the University of Oklahoma
    Inventor: Samuel A. Burstein
  • Enhancing growth of megakaryocytes in mammals using interleuking 6
    Patent number: 5087448
    Abstract: A therapeutic method for treating mammals by administering an effective dosage of a substance comprising interleukin 6 or interleukin 6 and interleukin 3 into the mammal for enhancing the growth of megakaryocytes and platelets.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: February 11, 1992
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Samuel A. Burstein