Abstract: The present invention relates to crystalline forms of a KRas G12C inhibitor and salt thereof. In particular, the present invention relates to crystalline forms of the KRas G12C inhibitor 2-[(2S)-4-[7-(8-chloro-1-naphthyl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile, pharmaceutical compositions comprising the crystalline forms, processes for preparing the crystalline forms and methods of use thereof.

Abstract: The present invention relates to crystalline forms of a KRas G12C inhibitor and salt thereof. In particular, the present invention relates to crystalline forms of the KRas G12C inhibitor 2-[(2S)-4-[7-(8-chloro-1-naphthyl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile, pharmaceutical compositions comprising the crystalline forms, processes for preparing the crystalline forms and methods of use thereof.

Abstract: A statistical language model may be used to simulate one or more users of a conversation. The statistical language model may be used to train a user to participate in a particular types of conversation by simulating communications by another type of user in the conversation. The communications may be simulated by selecting a simulation context from available simulation contexts and the simulation context may correspond to a difficulty level. Upon receiving a communication from a user, a responsive simulated communication may be generated by processing the received communication and the simulation context with the statistical language model. Upon completion of the simulation, another simulation context may be selected for the next simulation.

Abstract: The present invention relates to crystalline forms of a KRas G12C inhibitor and salt thereof. In particular, the present invention relates to crystalline forms of the KRas G12C inhibitor 2-[(2S)-4-[7-(8-chloro-1-naphthyl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile, pharmaceutical compositions comprising the crystalline forms, processes for preparing the crystalline forms and methods of use thereof.

Abstract: An example of an apparatus to connect a power distribution network with a mobile utility-scale energy storage unit is provided. The apparatus includes an enclosure to protect an interior space from weather elements. The apparatus further includes an interface device disposed within the enclosure. In addition, the apparatus includes a bellows extending from the enclosure and bellows connector to mate with a complimentary connector on a wall of an energy storage unit to form a weatherproof seal. The apparatus also includes a cable extending from the interface device through the bellows to connect the interface device to the energy storage unit to transfer energy between the power distribution network and the energy storage unit.

Abstract: An enterprise inventory management system, and methods of use thereof, utilizing novel functionalities. The system includes a centralized global inventory database subsystem for cataloging a plurality of inventory items from a plurality of remote physical locations, each of the items identified by at least a unique identification code; and, a plurality of localized radio frequency identification (RFID) interrogator subsystems associated with a corresponding plurality of remote physical locations, wherein each of the localized RF interrogator subsystems is operative to read RFID tags associated with ones of the plurality of inventory items located at its associated physical location, wherein each of the RFID tags is programmed with at least a unique identification code for its associated item.

Abstract: An example of a system to provide energy storage capacity moveable between multiple locations is provided. The system includes a plurality of docking stations, wherein each docking station is connected to a power distribution network. In addition, the system includes an energy storage unit to connect to a first docking station selected from the plurality of docking stations. Furthermore, the system includes a transporter onto which the energy storage unit is mounted to transport the energy storage unit from the first docking station to a second docking station.

Abstract: An example of an apparatus to connect a power distribution network with an energy storage unit. The apparatus includes a mobile platform. In addition, the apparatus includes a connection system to connect with an energy storage unit and to receive a current from the energy storage unit. Furthermore, the apparatus includes a transformer mounted on the mobile platform to convert the voltage from the connection system to the voltage of a power distribution network. The apparatus also includes an output cable to connect with the power distribution network.

Abstract: Disclosed herein is a cooking system for cooking food, the system including a housing defining a hollow chamber configured to receive a food container. The housing has an upper portion defining an opening to the hollow chamber. A food container having a hollow container interior is positionable within the hollow chamber. An end of the food container extends above the upper portion of the housing when the container is installed within the hollow chamber. A lid is moveably attached to the housing and is moveable between a first position that covers the upper portion of the housing and the opening to the hollow chamber when the food container is installed within the hollow chamber and a second position where the lid does not cover the opening to the hollow chamber. At least one heating element is associated with at least one of said lid and said housing.

Abstract: The present invention relates to crystalline forms of a KRas G12C inhibitor and salt thereof. In particular, the present invention relates to crystalline forms of the KRas GT2C inhibitor 2-[(2S)-4-[7-(8-chloro-1-naphthyI)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yI]-1-(2-fluoroprop-2-enoyi)piperazin-2-yl]acetonitrile, pharmaceutical compositions comprising the crystalline forms, processes for preparing the crystalline forms and methods of use thereof.

Abstract: Disclosed herein is a cooking system for cooking food, the system including a housing having a hollow interior, a lid movable relative to the housing, at least one heating element associated with one of the housing and the lid, wherein the cooking system is operable in a plurality of modes including a conductive cooking mode and a convective cooking mode, wherein in the conductive cooking mode the cooking system is operable as a conductive cooker and in the convective cooking mode the cooking system is operable as a convection cooker.

Abstract: Disclosed herein is a cooking system for cooking food, the system including a housing defining a hollow chamber configured to receive a food container. The housing has an upper portion defining an opening to the hollow chamber. A food container having a hollow container interior is positionable within the hollow chamber. An end of the food container extends above the upper portion of the housing when the container is installed within the hollow chamber. A lid is moveably attached to the housing and is moveable between a first position that covers the upper portion of the housing and the opening to the hollow chamber when the food container is installed within the hollow chamber and a second position where the lid does not cover the opening to the hollow chamber. At least one heating element is associated with at least one of said lid and said housing.

Abstract: The present disclosure pertains to pharmaceutically acceptable salts of fospropofol and their use to treat migraine.

Abstract: A cooking system for cooking food is provided, the system including a housing defining a hollow chamber configured to receive a food container. The housing has an upper portion defining an opening to the hollow chamber. A lid is configured to cover the upper portion of the housing and the opening to the hollow chamber in a closed position. The lid is moveable to an open position where the lid does not cover the opening to the hollow chamber. At least one heating element is associated with at least one of the housing and the lid. The cooking system is operable in a plurality of modes including a pressure cooking mode and a dry cooking mode. In the pressure cooking mode, the cooking system is operable as a pressure cooker and in the dry cooking mode, the cooking system is operable as a dry cooker.

Abstract: Disclosed herein is a cooking system for cooking food, the cooking system being functional in a plurality of cooking modes. The cooking system includes a housing defining a hollow chamber configured to receive a food container. The housing has an upper portion defining an opening to the hollow chamber. The cooking system includes a first lid configuration for use in at least a first cooking mode, a second lid configuration for use in at least a second cooking mode. A first lid detection sensor is configured to detect a closed condition of said first lid configuration and a second lid detection sensor is configured to detect a closed condition of said second lid configuration.

Abstract: The present disclosure pertains to pharmaceutically acceptable salts of fospropofol and their use to treat migraine.

Abstract: A cooking system for cooking food includes a housing defining a hollow chamber configured to receive a food container. The housing has an upper portion defining an opening to said hollow chamber. A lid is movable relative to said housing. The lid contacts the housing in a closed position about the upper portion of the housing to close the opening to the hollow chamber. At least one heating element is associated with at least one of said housing and said lid. The cooking system is operable in a plurality of cooking modes including a pressure cooking mode and a convective cooking mode. In said pressure cooking mode, the cooking system is operable as a pressure cooker and in said convective cooking mode, the cooking system is operable as a convection cooker.

Abstract: In some applications, it may be desired to process a message to determine an intent of the message, where the intent indicates the meaning of the message. An intent classifier may be used to determine the meaning of a message by processing the message to compute a message embedding vector that represents the message in a vector space. Each possible intent may be represented by a prototype vector, and the intent of the message may be determined by comparing the message embedding to one or more prototype vectors, such as by selecting an intent whose prototype vector is closest to the message embedding. An intent classifier may be used, for example, (i) to implement an automated communications system with states where each state is associated with a subset of the possible intents or (ii) for processing usage data of a communications system to update the intents of the communications system.

Abstract: Disclosed herein is a cooking system for cooking food, the system including a housing having a hollow interior, a lid movable relative to the housing, at least one heating element associated with one of the housing and the lid, wherein the cooking system is operable in a plurality of modes including a conductive cooking mode and a convective cooking mode, wherein in the conductive cooking mode the cooking system is operable as a conductive cooker and in the convective cooking mode the cooking system is operable as a convection cooker.

Abstract: A statistical language model may be used to simulate one or more users of a conversation. The statistical language model may be used to train a user to participate in a particular types of conversation by simulating communications by another type of user in the conversation. The communications may be simulated by selecting a simulation context from available simulation contexts and the simulation context may correspond to a difficulty level. Upon receiving a communication from a user, a responsive simulated communication may be generated by processing the received communication and the simulation context with the statistical language model. Upon completion of the simulation, another simulation context may be selected for the next simulation.