Abstract: The invention relates to an online web-based medical database and collaboration tool that can be used by surgeons, hospitals, medical institutions, manufacturers and others to collect, store, analyze and harvest clinical and radiologic data. The clinical registry system includes a registry database and a registry processor in electrical communication with the registry database and performing operations on the registry database. The registry database stores patient data from a plurality of sites, a plurality of registry groups and an indicator for each of the plurality of sites identifying which of the plurality of registry groups each site is a member. The members of a registry group have access to aggregated data and comparative reports of all the registry group members in real-time. Each site may be a member of one registry group, multiple registry groups, or no registry groups.