Abstract: A light detection and ranging (LIDAR) system can emit light toward an environment and detect responsively reflected light to determine a distance to one or more points in the environment. The reflected light can be detected by a plurality of plurality of photodiodes that are reverse-biased using a high voltage. Signals from the plurality of reverse-biased photodiodes can be amplified by respective transistors and applied to an analog-to-digital converter (ADC). The signal from a particular photodiode can be applied to the ADC by biasing a respective transistor corresponding to the particular photodiode while not biasing transistors corresponding to other photodiodes. The gain of each photodiode/transistor pair can be controlled by adjusting the bias voltage applied to each photodiode using a digital-to-analog converter. The gain of each photodiode/transistor pair can be controlled based on the detected temperature of each photodiode.

Abstract: Provided herein are methods of performing knee surgery, which include comparing a lateral distal femoral angle (LDFA) of the knee with a medial proximal tibial angle (MPTA) of the knee and determining a pre-disease alignment of the knee therefrom. Additionally, prognostic and diagnostic methods for use in knee surgery as well as methods of determining an angle of resection for a distal femur and/or a proximal tibia during knee surgery are provided herein. Also provided is an apparatus for assisting a surgeon in performing surgery on a knee of a patient, the apparatus comprising a processor configured for performing the aforementioned methods. A computer-readable medium having stored thereon a computer program, which, when executed by a computer, causes the computer to perform the aforementioned methods is also provided.

Abstract: Methods of applying a polymeric coating to a rear face surface of golf club heads with variable face thickness are disclosed herein. The coating, which preferably comprises polyurea, improves the durability of the face and reduces the hits to failure ratio of the golf club head. The coating improves the performance of the golf club head because it allows for reduction in overall face thickness and easy post-process manipulation to allow for fine-tuning of mass properties after production. The reduction in thickness leads to overall weight reduction, because the polymer is roughly a quarter of the density of titanium or stainless steel, and also reinforces the face, thereby increasing the lifespan of the club.

Abstract: In one embodiment, the example thermal expansion support systems decrease the stress within the one or more components and piping segments within a high temperature system caused by thermal expansion. The exemplary thermal expansion support systems may provide a counterbalancing force on the components and piping segments of the high temperature system, which may allow the components and piping segments a free range of motion to counterbalance the stress caused by thermal expansion of the high temperature system. In some embodiments, one example thermal expansion support system may utilize a counterweight system. In another embodiment, an example thermal expansion support system may utilize active system components, such as actuators, hydraulics, electric motors, or other similar devices to provide a counterbalancing force on the one or more components of the high temperature system.

Abstract: Provided herein is method for, among other things, estimating the number of sequence variations in a sample of DNA. In some embodiments, the method can be used to estimate the mutational load of a sample. In some embodiments, the method makes use of a set of primers that have 3? ends that specifically hybridizes to a sequence that is repeated multiple times in the genome. Thermocycling a reaction mix containing the primers may produce a reaction product comprising at least 50 amplicons having a total length of at least 100 kb. This product can be sequenced to provide an estimate of the number of sequence variations in the sample, and thus the mutational load of the sample.

Abstract: A wearable computing device with bio-signal sensors and a feedback module provides an interactive mediated reality (“VR”) environment for a user. The bio-signal sensors receive bio-signal data (for example, brainwaves) from the user and include bio-signal sensors embedded in a display isolator, having a deformable surface, and having an electrode extendable to contact the user's skin. The wearable computing device further includes a processor to: present content in the VR environment via the feedback module; receive bio-signal data of the user from the bio-signal sensor; process the bio-signal data to determine user states of the user, including brain states, using a user profile; modify a parameter of the content in the VR environment in response to the user states of the user. The user receives feedback indicating the modification of the content via the feedback module.

Abstract: Autonomous aerial navigation in low-light and no-light conditions includes using night mode obstacle avoidance intelligence, training, and mechanisms for vision-based unmanned aerial vehicle (UAV) navigation to enable autonomous flight operations of a UAV in low-light and no-light environments using infrared data.

Abstract: A multi-zone temperature testing system includes a test device having components, a multi-zone temperature testing device that is coupled to the test device and that includes a first thermoelectric module that is located adjacent a first subset of the components and a second thermoelectric module that is located adjacent a second subset of the components, and a temperature control subsystem that is coupled to the multi-zone temperature testing device. The temperature control subsystem controls the first thermoelectric module in the multi-zone temperature testing device to produce a first heat flux that provides a testing temperature for the first subset of the components, and controls the second thermoelectric module in the multi-zone temperature testing device to produce a second heat flux that is different than the first heat flux and that provides the testing temperature for the second subset of the components.

Abstract: In an embodiment, a modular augmented reality display is provided that incorporates prescription eyewear that can be used separately by the wearer. In an embodiment, an image is generated from a removable display attached to the eyewear and directed into the edge of a prescription lens, which acts as a waveguide. The image is internally reflected within the prescription lens, and is directed to the wearer by an image combiner embedded within the prescription lens. In an embodiment, the augmented reality display includes a wearable belt pouch that includes a battery and support electronics connected to the eyewear so that the weight on the eyewear is reduced.

Abstract: In one embodiment, a computing system accesses a set of 3D locations associated with features in an environment previously captured by a camera from a previous camera pose. The computing system determines a predicted camera pose using the previous camera pose and motion measurements generated using a motion sensor associated with the camera. The computing system projects the set of 3D locations toward the predicted camera pose and onto a 2D image plane associated with the camera. The computing system generates, based on the projected set of 3D locations on the 2D image plane, an activation map specifying a subset of the pixel sensors of the camera that are to be activated. The computing system instructs, using the activation map, the camera to activate the subset of pixel sensors to capture a new image of the environment. The computing system reads pixel values of the new image.

Abstract: The present invention relates to hydrogel prodrug compositions comprising cross-linked hyaluronic acid (HA), or a derivative or a salt thereof, wherein the cross-linker system comprises a biodegradable spacer, wherein the cross-linked HA comprises a conjugated drug-linker, and wherein the linker is capable of releasing the drug under physiological conditions. The present invention further relates to methods for preparing the hydrogel prodrug compositions. The present invention further relates to methods for treating an ocular condition using the hydrogel compositions.

Abstract: A version of a software application is determined to be analyzed. The states of toggles associated with the version of the software application are analyzed to identify changed states of at least a portion of the toggles. A changed state of the changed states comprises a state of a toggle of the toggles that has changed during execution of the version of the software application. The changed state has a corresponding time frame and a corresponding sequence number. The changed states are logged.

Abstract: A patient interface includes a frame assembly including connectors operatively attachable to headgear, a cushion assembly provided to the frame assembly and including a seal-forming structure structured to form a seal with the patient's nose and/or mouth, and an air delivery connector provided to the frame assembly and operatively connected to an air delivery tube for supplying the air at positive pressure along an air flow path. The cushion assembly is structured to releasably connect to the frame assembly independently of the air delivery connector. The air delivery connector is structured to releasably connect to the frame assembly independently of the cushion assembly.

Abstract: A detergent composition having a) from about 10% to about 60%, by weight of the composition, of a surfactant system wherein the surfactant system includes: i) at least 35%, by weight of the surfactant system, of nonionic surfactant and ii) from 5% to about 20%, by weight of the surfactant system, of amine oxide.

Abstract: In one embodiment, a method includes receiving sets of measurement parameters associated with a sensed object and respectively captured by sensors. The method includes determining a relative orientation between the sensors based on comparison of the received sets of measurement parameters. The method includes determining one or more calibration factors based on comparing the determined relative orientation between sensors to an expected relative orientation between the sensors. The method includes applying at least one of the determined calibration factors to one or more of the measurement parameters captured by the sensors.

Abstract: A liner for a ram configured to press a viscous material. The liner includes a liner wall and a circumferential lip. The liner wall is configured to abut a ram plate of the ram and includes a number of apertures configured to align with apertures of the ram plate. The liner wall and circumferential lip are configured to prevent the viscous material from contacting a ram surface and circumferential surface of the ram plate, thus making the ram easier to clean.

Abstract: Compositions and kits for exosome capture include an antibody specifically binding the human asparagine-linked glycosylation 6 homolog (ALG6). The compositions and kits may be employed in a method for diagnosing a disease or condition in a subject.

Abstract: A computer-implemented solution is provided to allow electronic locks to implement commands more complex than simply opening or closing, such as timeframe-dependent commands, without requiring an access to the Internet at the time of access. At a remote computer, such as a cloud server, computer-readable instructions initially provided in a sequence of plain text characters, are encrypted into a user code using format preserving encryption (FPE) (e.g. FF3-1). The user code is communicated to the user. The user can then input the user code into the electronic lock via a numerical keypad or other suitable means. The lock is provided with computer functionalities which include a functionality to decrypt the cipher text of the user code back into plain text programming instructions using a decryption key, and execute it. The execution can involve determining whether one or more authorization condition is/are satisfied.

Abstract: A fish tape drum includes a frame and a drum portion rotatable relative to the frame. The drum portion has an outer wall and an inner wall. The first tape drum also includes a length of fish tape arranged between the inner wall and the outer wall. The fish tape drum further includes a constricting assembly configured to bias the length of fish tape toward the inner wall.