Abstract: An improved system and method for controlling the temperature of fluids during a mixing procedure or a chemical, pharmaceutical, or biological process is disclosed. One embodiment of the system comprises: a first collapsible bag including a perimeter and a maximum dimension thereacross measured at full expansion of the first collapsible bag; a first interior surface portion; a second interior surface portion; one or more welds connecting the first and second interior surface portions of the first collapsible bag so as to form a channel between the first and second interior surface portions, an inlet connected to a first portion of the channel; an outlet connected to a second portion of the channel, the channel defining a bulk fluid flow pathway through the first collapsible bag from the inlet to the outlet; and a first temperature-controlling surface in contact with a first exterior surface portion of the first collapsible bag.

Abstract: A high capacity leukocyte depletion filtration media incorporates a high specific surface area components with a matrix of fibers, yielding a filtration medium that removes leukocytes by at least 99.99%. The filtration medium uses a significantly low weight ratio of high specific surface area components to the matrix of fibers. The high specific area creates a multitude of adhesion sites for leukocytes while the low weight ratios allow good filtration flow rates. The filtration medium is incorporated into a filter device for removing leukocytes from biological fluids.

Abstract: A high capacity leukocyte depletion filtration media incorporates a high specific surface area components with a matrix of fibers, yielding a filtration medium that removes leukocytes by at least 99.99%. The filtration medium uses a significantly low weight ratio of high specific surface area components to the matrix of fibers. The high specific area creates a multitude of adhesion sites for leukocytes while the low weight ratios allow good filtration flow rates. The filtration medium is incorporated into a filter device for removing leukocytes from biological fluids.

Abstract: A high capacity leukocyte depletion filtration media incorporates a high specific surface area components with a matrix of fibers, yielding a filtration medium that removes leukocytes by at least 99.99%. The filtration medium uses a significantly low weight ratio of high specific surface area components to the matrix of fibers. The high specific area creates a multitude of adhesion sites for leukocytes while the low weight ratios allow good filtration flow rates. The filtration medium is incorporated into a filter device for removing leukocytes from biological fluids.

Abstract: Composite membranes having advantageous combinations of selectivity and permeability are prepared by the coating of a separation layer on a porous support layer containing a controlled amount of liquid in the range of from about 10% to about 90% by weight of the liquid present in the fully wet support layer.

Abstract: Polysulfone sulfonyl chlorides are described, which are useful as intermediates in the preparation of novel polysulfone sulfonamides.