Patents by Inventor Samuel Coe

Samuel Coe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20230212190
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 5, 2022
    Publication date: July 6, 2023
    Inventors: Celia DOMINGUEZ, Samuel COE, Peter David JOHNSON, Michael Edward PRIME, Christopher John BROWN, Sébastien René Gabriel GALAN, Paul Richard GILES, Jonathan BARD, Elise Lucienne Paulette GADOULEAU, Thomas Martin KRÜLLE, Daniel CLARK-FREW, John WITYAK, Alex KISELYOV, Sarah HAYES
  • COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF
    Publication number: 20220409600
    Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
    Type: Application
    Filed: May 24, 2022
    Publication date: December 29, 2022
    Inventors: Celia Dominguez, Jonathan Bard, Matthew R. Lee, Longbin Liu, Michael Edward Prime, Samuel Coe
  • Compounds for targeting mutant huntingtin protein and uses thereof
    Patent number: 11389438
    Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: July 19, 2022
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Jonathan Bard, Matthew R. Lee, Longbin Liu, Michael Edward Prime, Samuel Coe
  • Probes for imaging huntingtin protein
    Patent number: 11344637
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: May 31, 2022
    Assignee: CHDI FOUNDATION, INC.
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Brown, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 11059836
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: July 13, 2021
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Jonathan Bard, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20210060187
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 6, 2020
    Publication date: March 4, 2021
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Brown, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 10765764
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: September 8, 2020
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Brown, Sarah Hayes
  • COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF
    Publication number: 20200276176
    Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
    Type: Application
    Filed: February 24, 2020
    Publication date: September 3, 2020
    Inventors: Celia Dominguez, Jonathan Bard, Matthew R. Lee, Longbin Liu, Michael Edward Prime, Samuel Coe
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20200102328
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 2, 2019
    Publication date: April 2, 2020
    Inventors: Celia Dominguez, Samuel Coe, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Jonathan Bard, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 10479802
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: November 19, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Jonathan Bard, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20190167821
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: October 26, 2018
    Publication date: June 6, 2019
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Brown, Sarah Hayes
  • Probes for imaging Huntingtin protein
    Patent number: 10137211
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: November 27, 2018
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Brown, Sarah Hayes
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20170283436
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 28, 2015
    Publication date: October 5, 2017
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Alex Kiselyov, Christopher John Brown, Sébastien René Gabriel Galan, Michael Edward Prime, Paul Richard Giles, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, Peter David Johnson, Samuel Coe, Sarah Hayes
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20170056535
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 26, 2016
    Publication date: March 2, 2017
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Peter David Johnson, Thomas Martin Krulle, Daniel Clark-Frew, Duane Higgins, Matthew Robert Mills, Richard Waldron Marston, Samuel Coe, Samantha Louise Jones Green, Sarah Hayes