Abstract: A milling, drilling, and grinding spindle is provided to practically use the space between bearings. The spindle comprises a clamping chuck and a release unit for tensioning and releasing the clamping chuck. The tensioning and releasing is performed for exchanging a tool to be applied in each case. The release unit viewed in the longitudinal direction of the tool spindle is disposed between the clamping chuck and a drive of a shaft, and in particular between bearings of the shaft. The spindle may be motor or belt driven. The release unit may be formed by an integrated pneumatic or hydraulic cylinder and a connecting rod, which can be displaced by means of the cylinder.