Abstract: A method of measuring a radiation dosage during irradiation includes disposing a first sensor in a first package with a first biocontainer and disposing a second sensor in a second package with a second biocontainer. The method further includes placing the first package and the second package in a container and irradiation the container including the first package and the second package. During or after irradiation, a first radiation dosage associated with the first biocontainer is measured with the first sensor and a second radiation dosage associated with the second biocontainer is measured with the second sensor.

Abstract: A radiation dose sensor that measures a radiation dose of a biocontainer formed for a first material includes a first electrode, a second electrode, and a film. The first electrode has a plurality of first fingers. And the second electrode has a plurality of second fingers. The fingers of the first electrode extend towards and are interdigitated with the fingers of the second electrode that extend towards the first electrode with gaps formed between the first and second fingers. The film coats the interdigitated fingers and is disposed within the gaps. The film is formed of a second material that is similar to the first material that forms the biocontainer.

Abstract: A method for sterilizing by X-rays an assembly containing a single-use device intended to receive a biopharmaceutical fluid, comprising: placing a plurality of dosimeters, repeatedly passing the assembly in front of the X-ray radiation window, according to a first face then according to a second face of the assembly, at several irradiation power-time pairs (PTi), followed by mapping the radiation dose; and —determining an optimum power-time pair (PTopt) for which the mapping reveals that all dosimeters have recorded a radiation dose above a minimum sterility dose (Dmin), and for which the dosimeter associated with a fragile element of the single-use device records a radiation dose below a maximum dose (Dmax) defined as being the dose from which the X-ray irradiation deteriorates the fragile element.

Abstract: A radiation dose sensor that measures a radiation dose of a biocontainer formed for a first material includes a first electrode, a second electrode, and a film. The first electrode has a plurality of first fingers. And the second electrode has a plurality of second fingers. The fingers of the first electrode extend towards and are interdigitated with the fingers of the second electrode that extend towards the first electrode with gaps formed between the first and second fingers. The film coats the interdigitated fingers and is disposed within the gaps. The film is formed of a second material that is similar to the first material that forms the biocontainer.

Abstract: A method of sterilizing biocontainers including irradiating a biocontainer and measuring a radiation dose received by the biocontainer. The method also includes determining an ageing time of the biocontainer after irradiation based on the radiation dose received by the biocontainer and preventing use of the biocontainer before the ageing time has elapsed.

Abstract: A method of measuring a radiation dosage during irradiation includes disposing a first sensor in a first package with a first biocontainer and disposing a second sensor in a second package with a second biocontainer. The method further includes placing the first package and the second package in a container and irradiation the container including the first package and the second package. During or after irradiation, a first radiation dosage associated with the first biocontainer is measured with the first sensor and a second radiation dosage associated with the second biocontainer is measured with the second sensor.

Abstract: A method for sterilizing by X-rays an assembly containing a single-use device intended to receive a biopharmaceutical fluid, comprising: placing a plurality of dosimeters, repeatedly passing the assembly in front of the X-ray radiation window, according to a first face then according to a second face of the assembly, at several irradiation power-time pairs (PTi), followed by mapping the radiation dose; and —determining an optimum power-time pair (PTopt) for which the mapping reveals that all dosimeters have recorded a radiation dose above a minimum sterility dose (Dmin), and for which the dosimeter associated with a fragile element of the single-use device records a radiation dose below a maximum dose (Dmax) defined as being the dose from which the X-ray irradiation deteriorates the fragile element.

Abstract: The present invention concerns a method for preparing polyanilines by oxidative polymerization of aniline in an aqueous acid medium, comprising at least one synthesis step carried out in the presence of a) a monomer with formula (An) RmRo—C6H3—NHR? in which Ro, Rm and R? independently of each other, represent H or a linear or branched alkyl, alkoxy, alkylcarboxy or alkylsulfonic group, containing 1 to 6 carbon atoms, b) an acid, c) an oxidizing agent and d) a salt, characterized in that the acid is formic acid. The PANI deposited and dried on a support provides films with 80% of crystalline phase, having a strong alignment of ?-? interactions parallel to the surface. The PANI and the films obtained may be used as semiconductors and/or conductors.

Abstract: Process of producing a biopharmaceutical product includes providing a pouch unit including a pouch and at least one port, and optionally, a functional device; filling the pouch with the product; carrying out the production process, and at at least one stage thereof, using or generating a liquid or small solid incident body within the biopharmaceutical product; the pouch unit incorporating a support and replacement element formed by or integrated in the pouch wall, or in the port or functional device so as to be accessible from the inside space and be in direct physical contact with the contents of the pouch, arranged so as to be able to be loaded with the incident body and pass between the support and replacement element and the contents, such that the incident body is loaded on the support and replacement element when it is not or should not be within the biopharmaceutical product.

Abstract: The present invention concerns a method for preparing polyanilines by oxidative polymerization of aniline in an aqueous acid medium, comprising at least one synthesis step carried out in the presence of a) a monomer with formula (An) RmRo—C6H3—NHR? in which Ro, Rm and R? independently of each other, represent H or a linear or branched alkyl, alkoxy, alkylcarboxy or alkylsulfonic group, containing 1 to 6 carbon atoms, b) an acid, c) an oxidizing agent and d) a salt, characterized in that the acid is formic acid. The PANI deposited and dried on a support provides films with 80% of crystalline phase, having a strong alignment of ?-? interactions parallel to the surface. The PANI and the films obtained may be used as semiconductors and/or conductors.