Patents by Inventor Samuel Frank Berkovic

Samuel Frank Berkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the diagnosis and treatment of epilepsy
    Publication number: 20040229257
    Abstract: A method for the diagnosis of SMEI in a patient comprising:
    Type: Application
    Filed: March 23, 2004
    Publication date: November 18, 2004
    Inventors: Steven Petrou, Samuel Frank Berkovic, Ingrid Eileen Scheffer
  • Sodium-channel alpha1-subunit and their polypeptides and their treatment of generalised epilepsy with febrile seizures plus
    Publication number: 20040110706
    Abstract: The mutations D188V, V1353L, I1656M in the neuronal gene sodium-channel alpha1-subunit, SCN1A, are disclosed. The methods of using their associated polypeptides for treating sodium channel dysfunction disorders including generalised epilepsy are also disclosed.
    Type: Application
    Filed: October 8, 2003
    Publication date: June 10, 2004
    Inventors: Robyn Heather Wallace, John Charles Mulley, Samuel Frank Berkovic
  • Mutation associated with epilepsy
    Publication number: 20040038236
    Abstract: An isolated mammalian DNA molecule encoding a mutant &ggr;-aminobutyric acid (GABA) receptor subunit, wherein a mutation event selected from the group consisting of point mutations, deletions, insertions and rearrangements has occurred and said mutation event disrupts the functioning of an assembled GABA receptor, or an otherwise functional fragment or homologue thereof.
    Type: Application
    Filed: April 9, 2003
    Publication date: February 26, 2004
    Inventors: Robyn Heather Wallace, John Charles Mulley, Samuel Frank Berkovic, Louise Anne Harkin, Leanne Michelle Dibbens
  • Identification of two principal mutations in ion channels associated with idiopathic generalised epilepsies
    Publication number: 20030157535
    Abstract: A method for identifying the molecular defects responsible for the idiopathic generalised epilepsies (IGE), comprising the steps of: 1) providing sequence information for ion channel subunits; 2) screening a nucleic acid or peptide isolated from a patient affected by an IGE for molecular defects in the ion channel subunits in order to identify two principal defects associated with the IGE; and 3) correlating the two principal molecular defects identified with clinical observations in order to establish the combination of mutant subunits involved in the IGE.
    Type: Application
    Filed: April 16, 2003
    Publication date: August 21, 2003
    Inventor: Samuel Frank Berkovic