Patents by Inventor Samuel Freeman

Samuel Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250285767
    Abstract: Techniques for estimating a risk that a condition of a patient with a multiple myeloma (MM) precursor disease such as MGUS or SMM will progress into MM.
    Type: Application
    Filed: May 27, 2025
    Publication date: September 11, 2025
    Applicants: The Broad Institute, Inc., The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Lorenzo Trippa, Gad Getz, Irene M. Ghobrial, Anna Cowan, Federico Ferrari, Samuel Freeman
  • Patent number: 11479878
    Abstract: The invention provides methods of using low coverage sequencing to assess the relative fraction of tumor versus normal DNA in a sample, and to assess copy number alterations present in the sample.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: October 25, 2022
    Assignees: DANA-FARBER CANCER INSTITUTE, INC., THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gavin Ha, Viktor Adalsteinsson, Samuel Freeman
  • Publication number: 20220282333
    Abstract: The present invention provides methods of predicting a patient's response to immunotherapy, in particular checkpoint blockade therapy, and provides for treatments. Disclosed herein are novel combinations of factors identified in tumors used to predict response and provide for treatments. Also, disclosed are methods of treatment that can shift a tumor to a responder phenotype.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 8, 2022
    Inventors: Samuel Freeman, Moshe Sade-Feldman, Nir Hacohen, Gad Getz, Matthew Meyerson
  • Publication number: 20190078232
    Abstract: The invention provides methods of using low coverage sequencing to assess the relative fraction of tumor versus normal DNA in a sample, and to assess copy number alterations present in the sample.
    Type: Application
    Filed: March 16, 2017
    Publication date: March 14, 2019
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: GAVIN HA, VIKTOR ADALSTEINSSON, SAMUEL FREEMAN
  • Patent number: 4231061
    Abstract: This invention relates to the photographic reproduction of color or monochromatic still pictures as displayed on the face of a cathode-ray tube (CRT). The invention combines the arts of television and photographics to make possible the retention of still color photographs (slides) from a television screen. A "frame grabber" is used to stop the motion of a television image and hold it while a simple color photographic process captures it.
    Type: Grant
    Filed: April 9, 1979
    Date of Patent: October 28, 1980
    Inventor: Samuel Freeman
  • Patent number: D273591
    Type: Grant
    Filed: October 15, 1980
    Date of Patent: April 24, 1984
    Inventor: Samuel Freeman