Patents by Inventor Samuel J. Asirvatham

Samuel J. Asirvatham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210275080
    Abstract: Systems, methods, devices, and techniques for analyzing and applying features of a T-wave derived from an electrocardiogram. A computing system can receive a set of data that characterizes an electrocardiogram of a patient. The system can analyze the set of data to identify a T-wave that occurs in the electrocardiogram. The system can determine values of one or more features of the T-wave and provide the information that identifies the values of the one or more features of the T-wave to a user.
    Type: Application
    Filed: August 31, 2017
    Publication date: September 9, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Peter A. Noseworthy, Bo Qiang, Paul A. Friedman, Alan M. Sugrue, Vaclav Kremen, Bryan L. Striemer, Charles J. Bruce, Virend K. Somers, Kevin E. Bennet, Michael J. Ackerman, Samuel J. Asirvatham, John J. Dillon, Christopher V. DeSimone
  • Publication number: 20210244951
    Abstract: This document relates to methods and materials for providing stimulation or ablation to the stellate ganglion. For example, this document relates to methods and devices for providing stimulation or ablation to the stellate ganglion to modify blood pressure.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 12, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Yong-Mei CHA, Samuel J. ASIRVATHAM
  • Publication number: 20210228861
    Abstract: This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. ASIRVATHAM, Paul A. Friedman
  • Publication number: 20210219900
    Abstract: This document describes methods and materials for mapping and modulating repolarization. For example, this document relates to methods and devices for mapping and modulating repolarization to target atrial and ventricular arrhythmias to deliver electrical stimulation pacing, ablation and/or electroporation.
    Type: Application
    Filed: April 7, 2021
    Publication date: July 22, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Christopher J. McLEOD, Samuel J. Asirvatham
  • Publication number: 20210212761
    Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 15, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Mark B. Knudson
  • Patent number: 11058484
    Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: July 13, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Mark B. Knudson
  • Patent number: 11045133
    Abstract: Systems, methods, and computer program product embodiments are disclosed for filtering noise from an input signal. An embodiment accesses the input signal having a first harmonic frequency and having the noise. The embodiment determines a quiet period in the input signal. The embodiment stores samples of the noise of the input signal in a buffer during the quiet period. The embodiment subtracts the samples from a single cycle of the noise in the buffer from the input signal to create a filtered signal. The embodiment then repeats the determining, storing, and subtracting to refine the filtered signal.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: June 29, 2021
    Assignees: BioSig Technologies, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
  • Publication number: 20210187287
    Abstract: Devices and methods can be used to treat dermatologic disorders, hyperhidrosis, and wrinkles using DC electroporation. In some cases, such electroporation is essentially non-thermal modulation that can be used to ablate keratinocyte neoplasms, such as seborrheic keratosis, and other non-keratinocyte derived neoplasms of the skin and adnexal structures and related structures in other anatomic sites. In some implementations, the devices and methods described herein can be used for therapy delivery for the treatment of early or pre-malignant skin cancers. In some implementations, the devices and methods described herein can be used for treatment of hyperhidrosis and cosmetic issues.
    Type: Application
    Filed: June 10, 2019
    Publication date: June 24, 2021
    Inventors: Spencer A. Bezalel, Clark C. Otley, Samuel J. Asirvatham, Christian Lee Baum
  • Patent number: 11027115
    Abstract: This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: June 8, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Paul A. Friedman
  • Patent number: 11020589
    Abstract: Systems and methods for epicardial pacing are provided. For example, this document provides epicardial pacing using a percutaneously delivered bifurcated pacing lead that has multiple electrodes that are directionally insulated to prevent extracardiac stimulation, including prevention of phrenic stimulation. In addition, the devices, systems, and methods provided can be used for ablation, defibrillation, and/or defibrillation in combination with pacing.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: June 1, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Faisal F. Syed, Charles J. Bruce, Christopher V. DeSimone, Paul A. Friedman, Samuel J. Asirvatham, Tomas Kara, Pavel Leinveber, Miroslav Novak, Zdenek Starek, Jiri Wolf
  • Patent number: 11000202
    Abstract: This document describes methods and materials for mapping and modulating repolarization. For example, this document relates to methods and devices for mapping and modulating repolarization to target atrial and ventricular arrhythmias to deliver electrical stimulation pacing, ablation and/or electroporation.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: May 11, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Christopher J. McLeod, Samuel J. Asirvatham
  • Publication number: 20210106807
    Abstract: This document relates to materials and methods for circulatory bypass of a ventricle in the heart of a mammal. For example, materials and methods for bypassing a permanently or temporarily impaired left ventricle in the heart of a mammal (e.g., a human) are provided.
    Type: Application
    Filed: November 25, 2020
    Publication date: April 15, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Soon J. Park, Paul A. Friedman, Charles J. Bruce, Sudhir S. Kushwaha
  • Patent number: 10973573
    Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: April 13, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Mark B. Knudson
  • Publication number: 20210069465
    Abstract: Systems and methods for impairing smooth muscle tissue function using energy and/or pressure are described herein. The systems and/or methods may be used in some embodiments to target smooth muscle tissue in the bronchial passages.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 11, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Craig E. Daniels, Samuel J. Asirvatham
  • Publication number: 20210059759
    Abstract: Cystic lesions can be treated by electroporation. For example, this document describes methods and devices for endoscopic ultrasound-guided ablation of cystic lesions using a needle for electroporation.
    Type: Application
    Filed: September 6, 2018
    Publication date: March 4, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Barham K. Abu Dayyeh
  • Publication number: 20210044533
    Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.
    Type: Application
    Filed: October 28, 2020
    Publication date: February 11, 2021
    Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC, Samuel J. ASIRVATHAM
  • Publication number: 20200397525
    Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.
    Type: Application
    Filed: February 27, 2019
    Publication date: December 24, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Peter M. Pollak, Samuel J. Asirvatham, Charles J. Bruce, Paul A. Friedman
  • Patent number: 10869957
    Abstract: This document relates to materials and methods for circulatory bypass of a ventricle in the heart of a mammal. For example, materials and methods for bypassing a permanently or temporarily impaired left ventricle in the heart of a mammal (e.g., a human) are provided.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: December 22, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Soon J. Park, Paul A. Friedman, Charles J. Bruce, Sudhir S. Kushwaha
  • Publication number: 20200376274
    Abstract: Devices and methods can be used for artificial cardiac pacing and/or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 3, 2020
    Inventors: Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham
  • Publication number: 20200368527
    Abstract: A wearable device combines its existing functions (e.g., a headphone) with non-invasive autonomic modulation using tragus or other external auditory meatus stimulation. The wearable device can output audio to a user, such as music, podcast, etc., and further provide modulation of the vagus nerve via tragus stimulation or other external auditory meatus stimulation to treat various diseases.
    Type: Application
    Filed: May 20, 2020
    Publication date: November 26, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Samuel J. Asirvatham