Patents by Inventor Samuel J. Asirvatham

Samuel J. Asirvatham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200022752
    Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.
    Type: Application
    Filed: September 16, 2019
    Publication date: January 23, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Mark B. Knudson
  • Publication number: 20200022591
    Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device.
    Type: Application
    Filed: September 26, 2019
    Publication date: January 23, 2020
    Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav VLAJINIC, Samuel J. ASIRVATHAM
  • Publication number: 20200015687
    Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 16, 2020
    Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
  • Publication number: 20200008870
    Abstract: An example medical system for ablating and occluding the left atrial appendage is disclosed. The example system includes a catheter sized and shaped for vascular access and including an elongate body extending between a proximal end and a distal end. A first expandable member may be positioned near the distal end of the elongate body and have a first region configured to permeate a liquid therethrough. A first set of one or more electrodes may be arranged within the first expandable member and may be configured to deliver energy to the tissue region. An occlusive implant may be releasably secured to the distal end of the elongate body.
    Type: Application
    Filed: July 9, 2019
    Publication date: January 9, 2020
    Applicants: BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: SARAH MELISSA GRUBA, JAMES P. ROHL, JAMES A. KLOS, JOHN M. EDGELL, DOUGLAS DEAN PAGORIA, SAMUEL J. ASIRVATHAM
  • Publication number: 20190365250
    Abstract: Systems, methods, and computer program product embodiments are disclosed for displaying cardiac signals based on a signal pattern. An embodiment operates by accessing an input cardiac signal. The embodiment matches a portion of the input cardiac signal to a known signal pattern. The embodiment then displays an indication of a degree of the match.
    Type: Application
    Filed: August 16, 2019
    Publication date: December 5, 2019
    Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
  • Publication number: 20190336208
    Abstract: This document provides devices and methods for the treatment of heart conditions, hypertension, and other medical disorders. For example, this document provides devices and methods for treating atrial fibrillation by performing thoracic vein ablation procedures, including pulmonary vein myocardium ablation. In some embodiments, the ablation is performed in coordination with the delivery a pharmacological agent that can abate the formation of tissue stenosis or neointimal hyperplasia caused by the ablation.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 7, 2019
    Inventors: Samuel J. Asirvatham, David R. Holmes, JR.
  • Patent number: 10426545
    Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: October 1, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Mark B. Knudson
  • Publication number: 20190262019
    Abstract: This document relates to devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure.
    Type: Application
    Filed: May 8, 2019
    Publication date: August 29, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Barry A. Borlaug, Vojtech Melenovsky
  • Patent number: 10390879
    Abstract: This document provides devices and methods for the treatment of heart conditions, hypertension, and other medical disorders. For example, this document provides devices and methods for treating atrial fibrillation by performing thoracic vein ablation procedures, including pulmonary vein myocardium ablation. In some embodiments, the ablation is performed in coordination with the delivery a pharmacological agent that can abate the formation of tissue stenosis or neointimal hyperplasia caused by the ablation.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: August 27, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, David R. Holmes, Jr.
  • Publication number: 20190246966
    Abstract: Systems, methods, and other techniques for estimating the level of an analyte present in a patient during a time interval using electrocardiogram (ECG) signals. The estimate can be improved using information about the patient's posture.
    Type: Application
    Filed: September 12, 2017
    Publication date: August 15, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Michael J. Ackerman, Samuel J. Asirvatham, Itzhak Zachi Attia, Kevin E. Bennet, Charles J. Bruce, John J. Dillon, Jennifer L. Dugan, Dorothy J. Ladewig, Virend K. Somers
  • Publication number: 20190224477
    Abstract: Systems and methods for epicardial pacing are provided. For example, this document provides epicardial pacing using a percutaneously delivered bifurcated pacing lead that has multiple electrodes that are directionally insulated to prevent extracardiac stimulation, including prevention of phrenic stimulation. In addition, the devices, systems, and methods provided can be used for ablation, defibrillation, and/or defibrillation in combination with pacing.
    Type: Application
    Filed: March 27, 2019
    Publication date: July 25, 2019
    Applicants: Mayo Foundation for Medical Education and Research
    Inventors: Faisal F. Syed, Charles J. Bruce, Christopher V. DeSimone, Paul A. Friedman, Samuel J. Asirvatham, Tomas Kara, Pavel Leinveber, Miroslav Novak, Zdenek Starek, Jiri Wolf
  • Publication number: 20190216641
    Abstract: This document describes methods and materials for the treatment of pathological conditions, including arrhythmias and trauma, using temperature modulation via implantable devices. For example, this document relates to methods and devices for treating atrial and/or ventricular fibrillation by cooling the epicardium.
    Type: Application
    Filed: January 16, 2019
    Publication date: July 18, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Samuel J. Asirvatham
  • Publication number: 20190217110
    Abstract: This document describes methods and materials for reducing incision sizes for improving the treatment of pathological conditions, including arrhythmias and trauma, using temperature modulation via implantable devices. For example, this document describes methods and devices for treating atrial and/or ventricular fibrillation by cooling the epicardium.
    Type: Application
    Filed: January 2, 2019
    Publication date: July 18, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Samuel J. Asirvatham
  • Publication number: 20190183431
    Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
  • Patent number: 10307179
    Abstract: Pericardial modification devices and methods can be used for the treatment of heart conditions. For example, this document describes devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. In one example embodiment, a method for treating diastolic heart failure includes creating an opening in a patient's pericardial tissue, or removing a portion of the patient's pericardial tissue. The creation of the opening or the removing of the pericardial tissue reduces pressure exerted by the pericardial tissue on the patient's heart. The pericardial modification procedures are performed while avoiding trauma to the epicardial surface of heart as well as the phrenic nerves.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: June 4, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Barry A. Borlaug, Vojtech Melenovsky
  • Publication number: 20190142246
    Abstract: A visualization catheter includes an elongate shaft, a cap portion, and an offset balloon coupled to the distal end of the shaft. The elongate shaft includes a proximal end, a distal end, and a central axis defined therebetween. The cap portion is coupled to the distal end of the shaft. The cap portion also includes a visualization element and defines an aperture. The offset balloon is coupled to the distal end of the shaft and encapsulates the cap portion. The offset balloon defines a center point offset relative to the central axis of the shaft.
    Type: Application
    Filed: December 16, 2016
    Publication date: May 16, 2019
    Applicants: BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: BENN HORRISBERGER, JAMES P. ROHL, LANCE A. FREESEMAN, JAMES A. KLOS, JOEL T. EGGERT, ARJUN D. SHARMA, SAMUEL J. ASIRVATHAM
  • Publication number: 20190142300
    Abstract: Systems and methods capture and/or occlusion of selected body tissue using various tissue characteristics and/or techniques are described. In the context of left atrial appendage closure, the systems and methods can be used to capture the left atrial appendage while a closure instrument (suture, clip, ring, etc.) is placed over the appendage and tightened down or a closure method (ablation, cryogenic procedures, stapling, etc.) is performed to close the left atrial appendage.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 16, 2019
    Inventors: Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham, Trevor A. McCaw, Elliot Y. K. Hong
  • Patent number: 10279170
    Abstract: Systems and methods for epicardial pacing are provided. For example, this document provides epicardial pacing using a percutaneously delivered bifurcated pacing lead that has multiple electrodes that are directionally insulated to prevent extracardiac stimulation, including prevention of phrenic stimulation. In addition, the devices, systems, and methods provided can be used for ablation, defibrillation, and/or defibrillation in combination with pacing.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: May 7, 2019
    Assignees: Mayo Foundation for Medical Education and Research, St. Anne's University Hospital Brno
    Inventors: Faisal F. Syed, Charles J. Bruce, Christopher V. DeSimone, Paul A. Friedman, Samuel J. Asirvatham, Tomas Kara, Pavel Leinveber, Miroslav Novak, Zdenek Starek, Jiri Wolf
  • Publication number: 20190125439
    Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for assessing electroporation therapy applied to a tissue region of a patient. In certain instances, the apparatuses, systems, and methods may include one or more sensors configured to sense an application of electroporation energy by an electroporation device to determine a location of the electroporation device within the patient.
    Type: Application
    Filed: October 25, 2018
    Publication date: May 2, 2019
    Inventors: James P. Rohl, Sarah M. Gruba, Douglas D. Pagoria, Matthew Hein, Samuel J. Asirvatham, Chance M. Witt, Suraj Kapa
  • Publication number: 20190105435
    Abstract: This document relates to materials and methods for circulatory bypass of a ventricle in the heart of a mammal. For example, materials and methods for bypassing a permanently or temporarily impaired left ventricle in the heart of a mammal (e.g., a human) are provided.
    Type: Application
    Filed: September 21, 2018
    Publication date: April 11, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Soon J. Park, Paul A. Friedman, Charles J. Bruce, Sudhir S. Kushwaha