Abstract: Ionically cross-linked compositions containing carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are provided. Methods for manufacturing ionically cross-linked compositions of carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are also provided. Such compositions can be used by placing then in proximity to a tissue in need of lubrication or for prevention of adhesions and adhesion reformation.

Abstract: Ionically cross-linked compositions containing carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are provided. Methods for manufacturing ionically cross-linked compositions of carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are also provided. Such compositions can be used by placing then in proximity to a tissue in need of lubrication or for prevention of adhesions and adhesion reformation.

Abstract: Ionically cross-linked compositions containing carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are provided. Methods for manufacturing ionically cross-linked compositions of carboxypolysaccharides, polyalkylene oxides, polyhydroxyl organic anions, optionally divalent cations, and aqueous media are also provided. Such compositions can be used by placing then in proximity to a tissue in need of lubrication or for prevention of adhesions and adhesion reformation.

Abstract: Compositions and method of manufacturing carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, the functional groups of a bi-functional PEG molecule (PEG diglycidyl ether) are attached to different CPSs, thereby forming a covalently cross-linked composition. Such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles, and lubricants of tissues and medical instruments.

Abstract: Compositions and method of manufacturing carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, the functional groups of a bi-functional PEG molecule (PEG diglycidyl ether) are attached to different CPSs, thereby forming a covalently cross-linked composition. Such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles, and lubricants of tissues and medical instruments.

Abstract: Uses of compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS in the presence of NH4OH. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles, and lubricants of tissues and medical instruments.

Abstract: Compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS via an addition reaction. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. In certain of these embodiments, a PEG is linked to the CPS by way of an ether linkage, and in other embodiments, a PEG is linked to the CPS by way of an ester linkage, and in still further embodiments, PEG molecule(s) can be attached to CPS molecule(s) by way of both ether and ester linkages. Additional embodiments include PEG/CMC compositions where the PEG is a multi-branch PEG and/or a multi-arm PEG.

Abstract: Uses of compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS in the presence of NH4OH. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles, and lubricants of tissues and medical instruments.

Abstract: Compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Additional embodiments include PEG/CMC compositions where the PEG is a multi-branch PEG and/or a multi-arm PEG. PEG/CMC compositions can be made with desired viscoelastic properties, and such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles or lubrication of tissues and medical instruments.

Abstract: Compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Additional embodiments include PEG/CMC compositions where the PEG is a multi-branch PEG and/or a multi-arm PEG. PEG/CMC compositions can be made with desired viscoelastic properties, and such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles or lubrication of tissues and medical instruments.

Abstract: Compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Additional embodiments include PEG/CMC compositions where the PEG is a multi-branch PEG and/or a multi-arm PEG. PEG/CMC compositions can be made with desired viscoelastic properties, and such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles or lubrication of tissues and medical instruments.

Abstract: A non-linear perluoro polyalkylene or perfluoro polyarylene glycol of specific molecular conformation such as plate-like, spherical, or helical and having the formula CFx—[—(—RO—)n—CF3]4−x, wherein R is a C1-C10 linear or branched, substituted or unsubstituted fluoroalkyl or perfluoroalkyl group, or a substituted or unsubstituted fluoroaryl or perfluoroaryl group; x is an integer from 0 to 2; and n is a number between about 1 to about 20 is provided as a lubricant topcoat on a magnetic recording medium. The inventive lubricants are stable and provide increased bonded lube ratios compared to those of conventional lubricants.

Abstract: A material, preferably a magnetic data storage disc, includes a carbon layer covering at least a portion of a magnetic substrate and a crosslinked fluoropolymer layers covering at least a portion of the carbon layer. The crosslinked polymer layer has a thickness less than about 40 angstroms, and the carbon layer has a thickness less than about 100 angstroms. Preferred fluoropolymers include, for example, perfluoropolyethers. In some embodiments, the crosslinked fluoropolymer layer has a thickness at one point on the carbon layer greater than the thickness crosslinked fluoropolymer layer at another point on the carbon layer. The crosslinking generally is performed by irradiating the lubricant material on the carbon layer.

Abstract: A material, preferably a magnetic data storage disc, includes a carbon layer covering at least a portion of a magnetic substrate and a crosslinked fluoropolymer layers covering at least-a portion of the carbon layer. The crosslinked polymer layer has a thickness less than about 40 angstroms, and the carbon layer has a thickness less than about 100 angstroms. Preferred fluoropolymers include, for example, perfluoropolyethers. In some embodiments, the crosslinked fluoropolymer layer has a thickness at one point on the carbon layer greater than the thickness crosslinked fluoropolymer layer at another point on the carbon layer. The crosslinking generally is performed by irradiating the lubricant material on the carbon layer.

Abstract: A fluoropolyether having a nonfunctional silane end group is applied to a magnetic recording medium to form a lubricant topcoat thereon. In an embodiment of the present invention, no less than about 70% of the lubricant applied to the magnetic recording medium forms a bonded topcoat thereto.

Abstract: A lubricant composition comprising a first fluoropolyether and a second fluoropolyether having nitrogen containing end-group exhibits improved resistance to acid and thermal decomposition. Embodiments include a lubricant composition containing a perfluorinate polyalkylether admixed with a perfluorinated polyalkylether having amide terminal groups and applying the composition to the surface of a magnetic recording medium to form a homogeneous lubricant topcoat thereon.

Abstract: A fluoropolyether having a nonfunctional silane end group is applied to a magnetic recording medium to form a lubricant topcoat thereon. In an embodiment of the present invention, no less than about 70% of the lubricant applied to the magnetic recording medium forms a bonded topcoat thereto.

Abstract: The degree of bonding of a perfluoro polyether lubricant topcoat to a magnetic recording medium is improved by forming a polymeric phosphate derivative thereof. In an embodiment of the present invention, a perfluoro polyether phosphate polymer is formed with a molecular weight of about 1000 to about 5000, and applied to a magnetic recording medium to achieve a bonded lube ratio in excess of 0.9.

Abstract: A fluoropolyalkylether is prepared under mild reaction condictions by combining a fluoropolyalkylether substituted with one or more ester end-groups with an amine. Embodiments include combining: (i) a fluoropolyalkylether substituted with one or more ester end-groups having the formula: Rf—(COOR′)q with (ii) an amine having the formula: HNR1R2 and (iii) a solvent comprising a hydrofluorocarbon or a hydrofluoroether together with a lower alcohol at a temperature of from about 15° C. to about 30° C. to form the fluoropolyalkylether amide, where Rf is a perfluoropolyether, R′ is a lower alkyl group, q is 1-4; R1 is H and R2 is a C2-C4 or a C2-C4 substituted with at least one hydroxyl group.

Abstract: The degree of bonding of a perfluoro polyether lubricant topcoat to various protective overcoats of magnetic recording media is improved by forming a silyl ether of the perfluoro polyether lubricant. The degree of bonding of the lubricant topcoat to a particular protective overcoat is optimized and controlled by selecting a silyl ether end group having a high affinity for the protective overcoat.