Patents by Inventor Samuel J. Leibovich

Samuel J. Leibovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Wound treatment through inhibition of adenosine diphosphate ribosyl transferase
    Patent number: 6187822
    Abstract: The present invention pertains to a method for healing a wound in a mammal which comprises the steps of (A) providing a therapeutic wound healing composition comprising a therapeutically effective amount of an inhibitor of mono-adenosine diphosphate-ribosyl transferase to inhibit adenosine diphosphate-ribosylation of vascular endothelial growth factor; and (B) contacting the therapeutic wound healing composition with a wound in a mammal. This invention also pertains to wound healing compositions and to methods for preparing and using the wound healing compositions and the pharmaceutical products in which the therapeutic compositions may be used. This invention further pertains to therapeutic dermatological-wound healing compositions useful to minimize and treat diaper dermatitis and to methods for preparing and using the therapeutic dermatological-wound healing compositions.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: February 13, 2001
    Assignee: University of Medicine & Dentistry of NJ
    Inventor: Samuel J. Leibovich
  • Method and compositions for modulating neovascularization
    Patent number: 4808402
    Abstract: Tumor necrosis factors possess the unexpected ability to induce angiogenesis, or neovascularization. Novel methods and TNF-containing compositions and articles are provided for the induction of neovascularization and rapid wound healing.
    Type: Grant
    Filed: May 29, 1987
    Date of Patent: February 28, 1989
    Assignees: Northwestern University, Genentech, Inc.
    Inventors: Samuel J. Leibovich, Peter J. Polverini, H. Michael Shepard