Patents by Inventor Samuel Kulp

Samuel Kulp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the treatment of cancer cachexia
    Patent number: 11938105
    Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: March 26, 2024
    Assignee: Ohio State Innovation Foundation
    Inventors: Ching-Shih Chen, Christopher C. Coss, Samuel Kulp, Yu-Chou Tseng, Tanios Bekaii-Saab
  • Methods and compositions for the treatment of cancer cachexia
    Patent number: 11529323
    Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: December 20, 2022
    Assignee: Ohio State Innovation Foundation
    Inventors: Ching-Shih Chen, Christopher C. Coss, Samuel Kulp, Yu-Chou Tseng, Tanios Bekaii-Saab
  • Methods for suppressing cancer-related cachexia
    Patent number: 11219607
    Abstract: Methods of suppressing cachexia in a mammal with cancer comprising administering HDAC inhibitors are provided. Aspects include methods of administering an HDAC class 1 and 2b inhibitor in an amount effective to substantially maintain the mammal's weight compared to a mammal that does receive the HDAC class 1 and 2b inhibitor.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: January 11, 2022
    Assignee: OHIO STATE INNOVATION FOUNDATION
    Inventors: Ching-Shih Chen, Tanios Bekaii-Saab, Denis Guttridge, Guido Marcucci, Samuel Kulp, Yu-Chou Tseng
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER CACHEXIA
    Publication number: 20200289438
    Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.
    Type: Application
    Filed: September 13, 2018
    Publication date: September 17, 2020
    Inventors: Ching-Shih Chen, Christopher C. Coss, Samuel Kulp, Yu-Chou Tseng, Tanios Bekaii-Saab
  • METHODS FOR SUPPRESSING CANCER-RELATED CACHEXIA
    Publication number: 20150150832
    Abstract: Methods of suppressing cachexia in a mammal with cancer comprising administering HDAC inhibitors are provided. Aspects include methods of administering an HDAC class 1 and 2b inhibitor in an amount effective to substantially maintain the mammal's weight compared to a mammal that does receive the HDAC class 1 and 2b inhibitor.
    Type: Application
    Filed: November 19, 2014
    Publication date: June 4, 2015
    Inventors: Ching-Shih Chen, Tanios Bekaii-Saab, Denis Guttridge, Guido Marcucci, Samuel Kulp, Yu-Chou Tseng
  • Anti-agents
    Patent number: 8580827
    Abstract: A series of celecoxib derivatives defined by Formula I: were prepared and evaluated for their ability to inhibit the gram-negative bacteria Francisella tularensis. Pharmaceutical compositions including celecoxib derivatives and their use in methods for treating or preventing infection by Francisella tularensis in a subject are described.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: November 12, 2013
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Hao-Chieh Chiu, Samuel Kulp, John S. Gunn, Larry S. Schlesinger
  • ANTI-FRANCISELLA AGENTS
    Publication number: 20130005788
    Abstract: A series of celecoxib derivatives defined by Formula I: were prepared and evaluated for their ability to inhibit the gram-negative bacteria Francisella tularensis. Pharmaceutical compositions including celecoxib derivatives and their use in methods for treating or preventing infection by Francisella tularensis in a subject are described.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 3, 2013
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Ching-Shih Chen, Hao-Chieh Chiu, Samuel Kulp, John S. Gunn, Larry S. Schlesinger